Please assess the completion status of the following clinical trial:

Trial Title: Autologous Serum Efficacy Study in Patients With Severe Dry Eye

Study Design Characteristics:
- Allocation: RANDOMIZED
- Intervention Model: CROSSOVER
- Observational Model: None
- Primary Purpose: TREATMENT
- Time Perspective: None
- Masking: QUADRUPLE
- Phase: PHASE2
- Number of Arms: 2.0

Eligibility Criteria:
Inclusion Criteria:~* Age \> 18 years~* Severe Dry Eye, as defined by a OSDI score \> or = 40~Plus:~* Tear Break Up Time (TBUT) \< 5 seconds~* Cornea-conjunctival epithelial defects measured by Fluorescein staining and evaluation using the Oxford score.~Exclusion Criteria:~* No dry eye associated ocular disease~* Unable to comply protocol~* Severe anemia~* Previous use of autologous serum~* Concomitant use of other topical ocular drug~* Hypersensibility to any proposed interventions

- Gender: ALL
- Minimum Age: 18 Years
- Maximum Age: None
- Healthy Volunteers: f

Study Arms:
- Autologous serum -Systane (Type: OTHER): Crossover arm starting with autologous serum for 2 weeks. After a 1 week wash out with 0.9% sodium chloride, they continue with 2 weeks using artificial tears (Systane)
- Systane- Autologous serum (Type: OTHER): Crossover arm starting with artificial tears (Systane) for 2 weeks. After a 1 week wash out with 0.9% sodium chloride, they continue with 2 weeks using autologous serum.

Based on this trial design, predict the completion outcome and termination type (if applicable).