Please assess the completion status of the following clinical trial:

Trial Title: Study of Varespladib in Patients Hospitalized With Severe COVID-19

Study Design Characteristics:
- Allocation: RANDOMIZED
- Intervention Model: PARALLEL
- Observational Model: None
- Primary Purpose: TREATMENT
- Time Perspective: None
- Masking: QUADRUPLE
- Phase: PHASE2
- Number of Arms: 6.0

Eligibility Criteria:
Inclusion Criteria:~1. Participant is hospitalized with severe COVID-19 illness, defined in accordance with the Food and Drug Administration (FDA) Guidance for Industry - COVID-19: Developing Drugs and Biological Products for Treatment or Prevention (May 2020):~   a. Severe illness:~   i. Symptoms suggestive of severe systemic illness with COVID-19, which could include any symptom of moderate illness or shortness of breath at rest, or respiratory distress~   ii. Clinical signs indicative of severe systemic illness with COVID-19, such as respiratory rate ≥30 per minute, heart rate ≥125 per minute, SpO₂ ≤93% on room air at sea level or partial pressure of oxygen PaO₂/fraction of inspired oxygen FiO₂ \<300.~2. Participant has a positive virologic nucleic acid amplification test (NAAT) indicating SARS-CoV-2 infection in a sample collected \<72 hours prior to randomization.~3. Participant is between the ages of 18 and 80 years at the time of enrollment.~4. Participant provides informed consent prior to initiation of any study procedures.~5. Participant agrees to not participate in another clinical trial for the treatment of COVID 19 or SARS-CoV-2 through Day 28.~6. Participant has adequate hematologic status (in the absence of transfusion and growth factor support for at least 28 days), defined as follows:~   1. Absolute neutrophil count (ANC) ≥1.5 × 10⁹/L~  2. Platelet count ≥75 × 10⁹/L~  3. Hemoglobin ≥9 g/dL.~7. Participant has an Eastern Cooperative Oncology Group (ECOG) performance score of 0-2.~Exclusion Criteria:~1. Participant has mild, moderate, or critical COVID-19 defined in accordance with the FDA Guidance for Industry:~   a. Mild COVID-19:~   i. Symptoms of mild illness with COVID-19 that could include fever, cough, sore throat, malaise, headache, muscle pain, gastrointestinal symptoms, without shortness of breath or dyspnea~   ii. No clinical signs indicative of moderate, severe, or critical severity~   b. Moderate COVID-19:~   i. Symptoms of moderate illness with COVID-19, which could include any symptom of mild illness (fever, cough, sore throat, malaise, headache, muscle pain, gastrointestinal symptoms) or shortness of breath with exertion~   ii. Clinical signs suggestive of moderate illness with COVID-19, such as respiratory rate ≥20 breaths per minute, peripheral oxygen saturation (SpO₂) \>93% on room air at sea level, heart rate ≥90 beats per minute~   iii. No clinical signs indicative of severe or critical illness~   c. Critical COVID-19:~   i. Respiratory failure defined based on resource utilization requiring at least one of the following:~  * Endotracheal intubation and mechanical ventilation~  * Oxygen delivered by high-flow nasal cannula (\[HFNC\] heated, humidified, oxygen delivered via reinforced nasal cannula at flow rates \>20 L/min with fraction of delivered oxygen ≥0.5)~  * Noninvasive positive pressure ventilation~  * ECMO, or~  * Clinical diagnosis of respiratory failure (i.e., clinical need for one of the preceding therapies, but preceding therapies not able to be administered in setting of resource limitation)~   ii. Shock (defined by systolic blood pressure \<90 mmHg, or diastolic blood pressure \<60 mmHg or requiring vasopressors)~   iii. Multi-organ dysfunction/failure.~2. Participant has taken investigational medications within 7 days or 5 half-lives prior to enrollment, whichever is shorter.~3. Participant has required any new form of sedation, anxiolysis or central nervous system (CNS) depressant within the 48 hours prior to enrollment that would interfere with neurologic assessments at enrollment.~4. Has history of cerebrovascular accident or intracranial bleeding of any kind, acute coronary syndrome, myocardial infarction, or severe pulmonary hypertension.~5. Participant has chronic respiratory failure not associated with COVID-19, defined as prior need for home oxygen, need for home noninvasive positive-pressure ventilation (NIPPV) for reasons other than isolated sleep apnea, or other signs of chronic respiratory failure, in the investigator's judgment.~6. Upper gastrointestinal (GI) bleed evidenced by hematemesis, coffee-ground emesis or nasogastric aspirate, or hematochezia thought to originate from upper GI tract.~7. Participant has abnormal liver function defined as any 2 of the following at screening:~   1. Total bilirubin ≥2 × ULN~  2. Alanine aminotransferase (ALT) ≥3 × ULN~  3. Aspartate aminotransferase (AST) ≥3 × ULN~  4. Alkaline phosphatase (ALP) \>3 × ULN~  5. Gamma-glutamyl transferase (GGT) \>3 × ULN~8. Participant has an estimated glomerular filtration rate (eGFR) \<60 mL/min.~9. Participant has a known allergy or significant adverse reaction to varespladib-methyl or related compounds.~10. Participant is considered by the investigator to be unable to comply with protocol requirements due to geographic considerations, psychiatric disorders, or other compliance concerns; or has any serious medical condition or clinically significant laboratory, ECG, vital sign, or physical examination abnormality that would prevent study participation or place the participant at significant risk, as judged by the Investigator.~11. Participant is breast-feeding, pregnant, has a positive serum hCG pregnancy test, or is not willing to use a highly effective method of contraception for 14 days after treatment. Highly effective methods of contraception are as follows:~    1. Combined (estrogen- and progestogen-containing) hormonal contraception associated with inhibition of ovulation (oral, intravaginal, or transdermal)~   2. Progestogen-only hormonal contraception associated with inhibition of ovulation (oral, injectable, or implantable)~   3. Intrauterine device, intrauterine hormone-releasing system~   4. Bilateral tubal occlusion~   5. Vasectomized partner~   6. Sexual abstinence~   7. Double-barrier method (condoms, sponge, diaphragm, with spermicidal jellies, or cream).

- Gender: ALL
- Minimum Age: 18 Years
- Maximum Age: 80 Years
- Healthy Volunteers: f

Study Arms:
- Varespladib: 250 mg QD + Placebo + placebo (Type: EXPERIMENTAL): For 7 days, and in addition to institutional standard of care, participants will take 250 mg varespladib in the morning. In order to maintain the blind, they will also take 1 placebo tablet in the afternoon and 1 placebo tablet in the evening.
- Varespladib: 250 mg BID + placebo (Type: EXPERIMENTAL): For 7 days, and in addition to institutional standard of care, participants will take 250 mg varespladib in the morning and in the evening. In order to maintain the blind, they will also take 1 placebo tablet in the afternoon.
- Varespladib: 250 mg TID (Type: EXPERIMENTAL): For 7 days, and in addition to institutional standard of care, participants will take 250 mg varespladib in the morning, in the afternoon, and in the evening.
- Placebo (Type: PLACEBO_COMPARATOR): For 7 days, and in addition to institutional standard of care, participants will take 1 placebo tablet in the morning, in the afternoon, and in the evening.
- Varespladib: 250mg BID (Part 2 of trial) (Type: EXPERIMENTAL): Dose chosen for Part 2 was twice a day dosing. For 7 days, and in addition to institutional standard of care, participants will take 250 mg varespladib in the morning, and in the evening.
- Placebo (Part 2 of trial) (Type: PLACEBO_COMPARATOR): For 7 days, and in addition to institutional standard of care, participants will take 1 placebo tablet in the morning, and in the afternoon.

Based on this trial design, predict the completion outcome and termination type (if applicable).