Please assess the completion status of the following clinical trial:

Trial Title: Effects of Sacubitril/Valsartan Therapy on Biomarkers, Myocardial Remodeling and Outcomes.

Study Design Characteristics:
- Allocation: None
- Intervention Model: SINGLE_GROUP
- Observational Model: None
- Primary Purpose: OTHER
- Time Perspective: None
- Masking: NONE
- Phase: PHASE4
- Number of Arms: 1.0

Eligibility Criteria:
Inclusion Criteria:~Based on the USPI for sacubitril/valsartan, subjects eligible for inclusion in this study must fulfill all of the following criteria at screening and baseline:~1. Written informed consent must be obtained before any assessment is performed.~2. Men and women ≥ 18 years of age.~3. LVEF ≤ 40% subjects who are candidates for on-label sacubitril/valsartan treatment per standard of care.~4. New York Heart Association (NYHA) Functional class II-IV.~5. LVEF ≤40% via any local measurement within the past 6 months using echocardiography, multi gated acquisition scan (MUGA), CT scanning, MRI or ventricular angiography provided no subsequent study documenting an EF of \>40%. If the EF measurement is expressed as a value range, the average of the range endpoint values should be used as the EF.~6. If a subject is on a loop diuretic, they must be on a stable dose for 2 weeks prior to baseline.~Key Exclusion Criteria:~Subjects fulfilling any of the following criteria, at screening and prior to dispensing of study drug, are not eligible for inclusion in this study. No additional exclusions may be applied by the investigator, in order to ensure that the study population will be representative of all eligible subjects/subjects.~1. pregnant or nursing women~2. women of child bearing potential not using highly effective method of contraception during dosing and for 7 days after stopping study medication~3. History of hypersensitivity to any of the study drugs, including history of hypersensitivity to drugs of similar chemical classes, or allergy to angiotensin converting enzyme inhibitor (ACEIs), Angiotensin II Receptor Blockers (ARBs), or Neutral endopeptidase (NEP) inhibitors as well as known or suspected contraindications to the study drugs.~4. History of angioedema drug related or otherwise.~5. Requirement of treatment with either ACE inhibitor and/or ARB.~6. Subjects with a heart transplant or ventricular assistance device (VAD) or intent to transplant (on transplant list) or implant a VAD.~7. Subjects with a cardio resynchronization therapy devices (CRT/CRT-D) implanted within 6 months of screening visit.~8. Subjects who are currently taking inotropic agents.~9. Current or prior treatment with sacubitril/valsartan.~10. Subjects taking medications prohibited by the protocol.~11. Subjects with diabetes mellitus who are taking aliskiren.~12. Use of other investigational drugs within 5 half-lives of enrollment, or within 30 days until the expected pharmacodynamic effect has returned to baseline, whichever is longer.~13. Concomitant use of nesiritide.~14. Bile acid sequestering agents such as cholestyramine or colestipol are prohibited to avoid interference with study drug absorption.~15. Any hospital admission/discharge related to heart failure within 2 weeks prior to baseline.~16. The use of outpatient or inpatient i.v. diuretic therapy within 2 weeks prior to baseline.~17. Enrollment in another clinical trial within 30 days of screening.~18. Potassium \> 5.2 mEq/L at screening.~19. History of malignancy of any organ system (other than localized basal cell carcinoma of the skin), treated or untreated, within one year.

- Gender: ALL
- Minimum Age: 18 Years
- Maximum Age: None
- Healthy Volunteers: f

Study Arms:
- LCZ696(sacubitril/valsartan) (Type: OTHER): Subjects received sacubitril/valsartan (LCZ696) on Day 1. The initial dose was determined by the investigator and per the approved indication described in the United States prescribing information/package insert (USPI). The three doses available were: 24/26 mg (Dose Level 1), 49/51mg (Dose Level 2) and 97/103mg (Dose Level 3).~Titration of the dosage were performed per USPI at 2 to 4 week intervals as clinically tolerated until maximal tolerated or target dosage was achieved. Target dosage was sacubitril/valsartan 97/103 mg twice daily.

Based on this trial design, predict the completion outcome and termination type (if applicable).