Please assess the completion status of the following clinical trial:

Trial Title: Platelet Bioenergetics in TBI

Study Design Characteristics:
- Allocation: None
- Intervention Model: None
- Observational Model: CASE_CONTROL
- Primary Purpose: None
- Time Perspective: PROSPECTIVE
- Masking: None
- Phase: None
- Number of Arms: None

Eligibility Criteria:
Inclusion Criteria:~* Patients must have moderate to severe traumatic brain injury (Glasgow Coma Scale (GCS) 3-13) to be enrolled in the TBI or TBI with trauma groups.~* Patients enrolled in the TBI with polytrauma group must also exhibit polytrauma including concomitant traumatic brain injury, major trauma to the chest, abdomen, pelvis or extremities.~* Patients must be greater than or equal to 18 years of age and must be less than or equal to 50 years of age.~* Patients must be able to cooperate for a detailed neurologic exam.~* Patients must be consented and undergo first blood sampling within the first 12 hours (+/- 2 hours) after their traumatic brain injury to be enrolled in the TBI or TBI with trauma groups.~* Patients must be expected to survive to discharge, as assessed by their admitting neurosurgery team~Exclusion Criteria:~* For the control group only, patients who have experienced a TBI in the last 6 months.~* Diagnosis of platelet diseases or disorders, such as thrombocytopenia, thrombocytosis, or Von Willebrand disease.~* Platelet transfusion within the last six months.~* Comorbid regimen of Metformin within the last 6 months.

- Gender: ALL
- Minimum Age: 18 Years
- Maximum Age: 50 Years
- Healthy Volunteers: t

Study Arms:
- TBI without polytrauma (Type: None): Subjects who have experienced a severe traumatic brain injury (Glasgow Coma Scale (GCS) 3-13) within the last 12 hours, without additional polytrauma.
- TBI with polytrauma (Type: None): Subjects who have experienced a severe traumatic brain injury (Glasgow Coma Scale (GCS) 3-13) and polytrauma, including major trauma to the chest, abdomen, pelvis or extremities. within the last 12 hours.
- Healthy Control (Type: None): Subjects who have not experienced any TBIs within the last six months.

Based on this trial design, predict the completion outcome and termination type (if applicable).