Please assess the completion status of the following clinical trial:

Trial Title: The Effect of Dupilumab on Lung Inflammation and Related Changes in Airway Volumes Detectable by Functional Respiratory Imaging in Patients With Moderate-severe Asthma

Study Design Characteristics:
- Allocation: RANDOMIZED
- Intervention Model: PARALLEL
- Observational Model: None
- Primary Purpose: TREATMENT
- Time Perspective: None
- Masking: TRIPLE
- Phase: PHASE4
- Number of Arms: 2.0

Eligibility Criteria:
Inclusion Criteria:~* 18 to 70 years of age inclusive with the diagnosis of asthma based on Global Strategy for Asthma Management and Prevention (GINA) 2019 at the time of signing the informed consent~* History of ≥1 exacerbation(s) in the previous year~* Uncontrolled moderate to severe asthma (ACQ-5 ≥1.5) at visit (V)1 and V2, prior to randomization~* Pre-bronchodilator FEV1 ≤80% of predicted normal at V1 and V2, prior to randomization~* Exhibit bronchodilator reversibility (≥12% and 200 mL improvement in FEV1 post SABA administration) during screening, prior to randomization~* Blood eosinophil ≥300 cells /µL and FeNO ≥25 ppb during screening, prior to randomization~NOTES:~* Historical values of blood eosinophil count meeting the eligibility criterion measured within 6 months prior to SV1 in the absence of OCS treatment are allowed.~* FeNO value to be checked for eligibility at V2 as well. -Existing treatment with medium to high dose ICS in combination with a second controller (e.g. LABA, LTRA) ± a third controller. The dose regimen should be stable ≥1 month prior V1 and during screening.~Exclusion Criteria:~* Current smoker (cigarette or e-cigarette) or cessation of smoking within 1 year prior randomization~* Previous smoker with a smoking history \>10 pack-years~* Known hypersensitivity to dupilumab or any of its excipients~* A subject who experiences an asthma exacerbation (defined as a deterioration of asthma that results in emergency treatment, hospitalization due to asthma, or treatment with systemic steroids) during screening~* Current acute bronchospasm or status asthmaticus~* Diagnosed pulmonary (other than asthma) or systemic disease associated with elevated peripheral eosinophil counts~* History or clinical evidence of chronic obstructive pulmonary disease (COPD) including Asthma-COPD Overlap Syndrome (ACOS) or any other significant lung disease (eg, lung fibrosis, sarcoidosis, interstitial lung disease, pulmonary hypertension, bronchiectasis, Churg-Strauss Syndrome, etc)~* Active tuberculosis, latent untreated tuberculosis or a history of incompletely treated tuberculosis or non-tuberculous mycobacterial infection unless it is well documented by a specialist that the participants has been adequately treated and the treatment with a biologic agent can be initiated, in the medical judgment of the Investigator and/or infectious disease specialist. Tuberculosis testing would only be performed on a country by country basis according to the routine clinical practice and the local guidelines, if required by regulatory authorities or ethics committees~* History of or current evidence of clinically significant disease in any non-respiratory system (e.g. cardiovascular, hepatic, nervous system, gastrointestinal, endocrinological, rheumatological, dermatological), which, in the judgment of the Investigator, could interfere with the study or require treatment that might interfere with the study~* Current evidence of clinically significant oncological disease, which in the opinion of the investigator may interfere with the objectives of the study or put the subject at undue risk~* Participants with any of the following results at V1:~  * Positive (or indeterminate) hepatitis B surface antigen (HBs Ag) or~ * Positive Hepatitis B IgM core antibody (IgM HBc Ab) or~ * Positive total hepatitis B core antibody (total HBc Ab) confirmed by positive HBV DNA or~ * Positive hepatitis C antibody (HCV Ab) confirmed by positive HCV RNA~* History of human immunodeficiency virus (HIV) infection or positive HIV serology at V1~* Any biologic therapy (including experimental treatments and dupilumab) or any other biologic therapy/immunosuppressant within 3 months prior to V1~* Treatment with live (attenuated) vaccine within 4 weeks before V1. For participants who have vaccination with live, attenuated vaccines planned during the course of the study (based on national vaccination schedule/local guidelines), it will be determined, after consultation with a physician, whether the administration of vaccine can be postponed until after the end of the study, or preponed to before the start of the study without compromising the health of the participant:~  * Participants for whom administration of live (attenuated) vaccine can be safely postponed would be eligible to enroll into the study.~ * Participants who have their vaccination preponed can enroll in the study only after a gap of 4 weeks following administration of the vaccine.~* Treatment with oral corticosteroids (OCS) within 2 weeks prior to V1~* Enrolled in other ongoing studies regardless of the investigational product~* Treatment with an investigational drug within 1 month or within 5 half-lives (if known), whichever is longer, prior to V1~* Suspected or high risk of parasitic infection (helminthic infection), unless clinical and (if necessary) laboratory assessments have ruled out active infection prior to randomization~* Females who are lactating, breastfeeding, or who are pregnant~* Individuals accommodated in an institution because of regulatory or legal order; prisoners or subjects who are legally institutionalized~* Participants are dependent on the Sponsor or Investigator (in conjunction with Section 1.61 of the ICH GCP Ordinance E6)~* Participants are employees of the clinical study site or other individuals directly involved in the conduct of the study, or immediate family members of such individuals~* Sensitivity to any of the study interventions, or components thereof, or drug or other allergy that, in the opinion of the Investigator, contraindicates participation in the study~* Any country-related specific regulation that would prevent the subject from entering the study~The above information is not intended to contain all considerations relevant to a patient's potential participation in a clinical trial.

- Gender: ALL
- Minimum Age: 18 Years
- Maximum Age: 70 Years
- Healthy Volunteers: f

Study Arms:
- Dupilumab (Type: EXPERIMENTAL): Participants received a loading dose of dupilumab 600 mg as 2 subcutaneous (SC) injections on Day 1, followed by a single dupilumab 300 mg SC injection Q2W for 24 weeks along with a stable dose of medium to high ICS dose in combination with a second controller medication +/- a third controller.
- Placebo (Type: PLACEBO_COMPARATOR): Participants received placebo matched to dupilumab as 2 x 2 mL SC injections on Day 1, followed by a single SC injection Q2W for 24 weeks along with a stable dose of medium to high ICS dose in combination with a second controller medication +/- a third controller.

Based on this trial design, predict the completion outcome and termination type (if applicable).