Please assess the completion status of the following clinical trial:

Trial Title: Pharmacogenetics Informed Tricyclic Antidepressant Dosing (PITA)

Study Design Characteristics:
- Allocation: RANDOMIZED
- Intervention Model: PARALLEL
- Observational Model: None
- Primary Purpose: TREATMENT
- Time Perspective: None
- Masking: SINGLE
- Phase: PHASE4
- Number of Arms: 2.0

Eligibility Criteria:
Inclusion Criteria:~Patients are in- and outpatients, having a primary diagnosis of severe major depressive disorder (SCID-I diagnosis in agreement with DSM-5 criteria and a Hamilton Rating Scale for Depression score ≥ 19 (HAM-D-17-item version), aged 18-65 years, who, according to their physician, are eligible for treatment with a TCA (Nortriptyline (NOR), Clomipramine (CLOMI) or Imipramine (IMI)). The choice of the specific TCA is at the discretion of the physician in attendance.~Exclusion Criteria:~1. Psychotic depression~2. Bipolar I or II disorder.~3. Schizophrenia or other primary psychotic disorder.~4. Drug or alcohol dependence in the past 3 months.~5. Mental Retardation (IQ \< 80).~6. For women: pregnancy or possibility for pregnancy without adequate contraceptive measures.~7. Breastfeeding.~8. Serious medical illness affecting the CNS, including but not restricted to M Parkinson, SLE, brain tumour, CVA.~9. Relevant medical illness as contra-indication for TCA use, such as recent myocardial infarction.~10. Other drugs influencing the pharmacokinetics of the TCAs as based on a list of interacting drugs. In case of psychotropic co-medication only a benzodiazepine in a dose equivalent up to 4 mg lorazepam will be allowed.

- Gender: ALL
- Minimum Age: 18 Years
- Maximum Age: 65 Years
- Healthy Volunteers: f

Study Arms:
- Genotype-guided TCA treatment (Type: EXPERIMENTAL): Genotype guided dosing of the TCAs in patients with a PM,IM,EM or UM phenotype based on pharmacogenetic test.
- Standard TCA treatment (Type: ACTIVE_COMPARATOR): Standard dosing of TCA in patients with a PM,IM, EM or UM phenotype based on pharmacogenetic test

Based on this trial design, predict the completion outcome and termination type (if applicable).