Please assess the completion status of the following clinical trial:

Trial Title: Activated Protein C and Corticosteroids for Human Septic Shock

Study Design Characteristics:
- Allocation: RANDOMIZED
- Intervention Model: FACTORIAL
- Observational Model: None
- Primary Purpose: TREATMENT
- Time Perspective: None
- Masking: QUADRUPLE
- Phase: PHASE3
- Number of Arms: 4.0

Eligibility Criteria:
Inclusion Criteria:~* hospitalized in intensive care unit for less than 7 days~* septic shock for less than 24 hours~* at least one proven site of infection~* at least 2 organ dysfunction as defined by a SOFA score =or\> to 3 for at least 6 consecutive hours~* need for vasopressor (dopamine =or\>15µg/kg/min or epinephrine/norepinephrine at =or\>0,25 µg/kg/min for at least 6 consecutive hours, to maintain systolic arterial pressure at 90 mmHg or more OR mean arterial pressure at 6( mmHg or more~* informed consent~Exclusion Criteria:~* pregnancy or breath feeding~* decision not to resuscitate~* underlying disease with an estimated life expectancy of less than 1 month~* formal indication for corticosteroids~* recent surgery (ie within the past 72 hours) or a surgery at high risk of bleeding~* gastro-intestinal bleeding within the past 6 weeks~* chronic liver disease (Child C)~* recent trauma (ie within the past 72 hours)~* intracranial process~* history of stroke, CNS bleeding or traumatic brain injury within the past 3 months~* platelet counts of less than 30000 per cubic millimeter~* formal indication for curative anticoagulant; prophylactic use of heparin is allowed~* any condition of high risk of bleeding as per patient's primary physicians~* hypersensitivity of activated drotrecogin alpha or any other component of the drug~* no affiliation to a social security~Amendments to eligibility criteria were:~On 27/03/2008: Changes in following exclusion criteria :~* surgical procedure in the past 7 days was changed for surgical procedure within 72 hours, or any surgery associated with high risk of bleeding, or a planned surgery within 24 h.~* chronic liver disease was clarified as chronic liver disease with Child score C.~* severe thrombopenia was clarified as severe thrombopenia (\<30,000/mm3, before transfusion).~On 25/08/2009: The exclusion criteria: surgical procedure within 72 hours, or any surgery associated with high risk of bleeding, or a planned surgery within 24 h was changed for surgical procedure within 12 hours, or any surgery associated with high risk of bleeding~On 11/06/2010: the inclusion criteria: admitted to the ICU for \< 7 days was removed; and a new exclusion criteria was added: patients who had a previous episode of sepsis during the same hospital stay~On 18/04/2012: following the withdrawal of DAA from the market: the following exclusion criteria (only related to DAA) were removed :~1. any surgery in the past 12 hours, or any surgery associated with high risk of bleeding;~2. chronic liver disease with a Child score C;~3. recent trauma;~4. any intracranial mass, or stroke or head injury in the past 3 months;~5. severe thrombocytopenia (\< 30.000 /mm3, before platelet transfusion);~6. formal indication for anticoagulation, or any other condition associated with increased risk of bleeding, as appreciated by the patient's physician.

- Gender: ALL
- Minimum Age: 18 Years
- Maximum Age: None
- Healthy Volunteers: f

Study Arms:
- 1 (Type: PLACEBO_COMPARATOR): placebo of hydrocortisone, placebo of fludrocortisone and placebo of activated protein C
- 2 (Type: ACTIVE_COMPARATOR): Hydrocortisone plus fludrocortisone and a placebo of activated protein C
- 3 (Type: ACTIVE_COMPARATOR): placebo of hydrocortisone, placebo of fludrocortisone and activated protein C
- 4 (Type: ACTIVE_COMPARATOR): hydrocortisone plus fludrocortisone plus activated protein C

Based on this trial design, predict the completion outcome and termination type (if applicable).