Please assess the completion status of the following clinical trial:

Trial Title: Topical Sirolimus Ointment for Cutaneous Angiofibromas in Subjects With Tuberous Sclerosis Complex

Study Design Characteristics:
- Allocation: RANDOMIZED
- Intervention Model: PARALLEL
- Observational Model: None
- Primary Purpose: TREATMENT
- Time Perspective: None
- Masking: QUADRUPLE
- Phase: PHASE2
- Number of Arms: 3.0

Eligibility Criteria:
Inclusion Criteria:~1. Generally healthy males or non-pregnant females aged 2 to 21 years, inclusive, at the time of screening.~2. Diagnosis of TSC with visible facial angiofibromas of at least grade 3 up to grade 5, inclusive, based on the IGA.~3. Subjects with 3 or more isolated, measurable lesions of facial angiofibroma, with color grading score ≥2 for each of the 3 lesions.~4. Females of childbearing potential must have a negative urine pregnancy test (or a negative serum pregnancy test if a urine pregnancy test cannot be obtained) (For China, different pregnancy test would be followed) and if sexually active or become sexually active during the study, must agree to use an effective form of birth control for the duration of the study. Females using oral contraceptives must also use a barrier method of contraception during the study. Sexually active male subjects and/or their female partners should also use appropriate contraception.~   Effective contraception is defined as follows:~  * Oral/implant/injectable/transdermal/estrogenic vaginal ring contraceptives, intrauterine device, condom with spermicide, diaphragm with spermicide.~  * Abstinence or partner's vasectomy are acceptable if the female agrees to implement one of the other acceptable methods of birth control if her partner changes.~5. The subject and/or their parent or guardian must be willing and able to provide written informed consent/assent.~6. Willing and able to comply with all trial requirements.~7. Subject or parent/guardian must be able to complete the subject self-assessment survey and subject diary in English or another language into which the documents have been officially translated.~8. Subjects should be in good general health based on the subject's medical history, physical exam, and impression of the study doctor.~   Exclusion Criteria:~9. Has any chronic or acute medical condition, that in the opinion of the investigator, may pose a risk to the safety of the subject during the trial period, or may interfere with the assessment of safety or efficacy in this trial.~10. Has received oral therapy or topical therapy of an mTOR inhibitor (sirolimus, temsirolimus, or everolimus) within 1 month of Baseline or other dermatological treatment to facial angiofibromas within 1 month of baseline. (Sunscreen is expected to be used in this patient population and is not considered treatment.)~11. Is currently receiving any form of immunosuppression therapy or has previously experienced significant immune dysfunction.~12. Has a history of sensitivity to any component of the investigational product.~13. Is pregnant, plans to become pregnant during the course of the study, or is breastfeeding.~14. Has other dermatologic conditions, pigmentation, scarring, pigmented lesions or sunburn in the treatment area that would preclude or prevent adequate assessment of changes to their facial angiofibromas.~15. Has facial hair (e.g., beard, sideburns, mustache) that could interfere with study assessments.~16. Has had laser surgery or cryotherapy to facial angiofibromas within 6 months preceding study entry.~17. Requires the use of any concomitant medication that, in the investigator's opinion, has the potential to cause an adverse effect when given with the investigational product or will interfere with the interpretation of the study results (see Section 16.1 Appendix 1 for Potential Drug Interactions).~18. Has participated in another clinical trial or received an investigational product within 3 months prior to screening.

- Gender: ALL
- Minimum Age: 2 Years
- Maximum Age: 21 Years
- Healthy Volunteers: f

Study Arms:
- Arm 1 (Type: ACTIVE_COMPARATOR): Sirolimus 0.2% ointment applied topically hs x 12 weeks
- Arm 2 (Type: ACTIVE_COMPARATOR): Sirolimus 0.4% ointment applied topically hs x 12 weeks
- Arm 3 (Type: PLACEBO_COMPARATOR): Placebo ointment applied topically hs x 12 weeks

Based on this trial design, predict the completion outcome and termination type (if applicable).