Please assess the completion status of the following clinical trial:

Trial Title: Intermittent or Continuous Acetylsalicylic Acid and Gene Expression in the Nasal Tissue of Current Smokers

Study Design Characteristics:
- Allocation: RANDOMIZED
- Intervention Model: PARALLEL
- Observational Model: None
- Primary Purpose: PREVENTION
- Time Perspective: None
- Masking: DOUBLE
- Phase: PHASE2
- Number of Arms: 2.0

Eligibility Criteria:
Inclusion Criteria:~* Male or female current tobacco smokers with \>= 20 pack years of self-reported smoking exposure and an average use of \>= 10 cigarettes/day~* Karnofsky \>= 70%~* Leukocytes \>= 3,000/microliter~* Absolute neutrophil count \>= 1,500/microliter~* Hematocrit within normal institutional limits~* Platelets within normal institutional limits~* Total bilirubin =\< 1.5 × institutional upper limit of normal (ULN)~* Aspartate aminotransferase (AST) (serum glutamic oxaloacetic transaminase \[SGOT\])/alanine aminotransferase (ALT) (serum glutamate pyruvate transaminase \[SGPT\]) =\< 1.5 × institutional ULN~* Creatinine =\< the upper institutional limits~* Prothrombin time (PT)/partial thromboplastin time (PTT) within normal institutional limits~* Fertile subjects must use adequate contraception (abstinence, barrier methods, or birth control pills) prior to study entry and for the duration of study participation~* Participants may have a history of indeterminate pulmonary nodule(s) by chest imaging if nodule follow-up has been completed or the study procedures would not interfere with nodule follow-up~* Ability to understand and the willingness to sign a written informed consent document~Exclusion Criteria:~* History of allergic reaction to aspirin or attributed to compounds of similar chemical or biologic composition to aspirin, including other nonsteroidal anti-inflammatory drugs (NSAIDs)~* Gastric intolerance attributable to ASA or NSAIDs~* History of gastric ulcer within the past 5 years (with or without bleeding)~* Use of ASA or NSAIDs for more than 5 days per month within 3 months of enrollment~* Not willing or are unable to refrain from use of any non-study ASA or NSAIDs during the study period~* Adult asthma~* Chronic, current or recent (within the past three months) use of leukotriene antagonists~* Require chronic anticoagulation or anti-platelet therapy~* History of bleeding disorder or hemorrhagic stroke~* Chronic, current or recent (within the past three months) use of glucocorticoids (systemic, topical and/or nasal sprays)~* History of chronic sinusitis or recent nasal polyps~* Not willing or are unable to limit alcohol consumption to =\< 2 alcoholic beverages a day during the study period~* Pregnant or lactating women; breastfeeding should be discontinued if the mother is treated with aspirin; should a woman become pregnant or suspect she is pregnant while participating in this study, she should inform her study physician immediately~* Participants may not be receiving any other investigational agents~* Uncontrolled intercurrent illness including, but not limited to, ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements~* Have a known history of inability to absorb an oral agent~* Invasive cancer within the past five years except non-melanoma skin cancer~* Urine cotinine level, if collected at screening, does not confirm active smoking status

- Gender: ALL
- Minimum Age: 18 Years
- Maximum Age: None
- Healthy Volunteers: t

Study Arms:
- Arm I (continuous aspirin) (Type: EXPERIMENTAL): Participants receive aspirin PO QD for 12 weeks.
- Arm II (intermittent aspirin) (Type: EXPERIMENTAL): Participants receive placebo PO QD during weeks 1, 3, 5, 7, 9, and 11 and aspirin PO QD during weeks 2, 4, 6, 8, 10, and 12.

Based on this trial design, predict the completion outcome and termination type (if applicable).