Please assess the completion status of the following clinical trial:

Trial Title: Crossover Study to Assess the Relative Bioavailability and Bioequivalence of Niraparib Tablet Compared to Niraparib Capsule

Study Design Characteristics:
- Allocation: RANDOMIZED
- Intervention Model: CROSSOVER
- Observational Model: None
- Primary Purpose: TREATMENT
- Time Perspective: None
- Masking: NONE
- Phase: PHASE1
- Number of Arms: 6.0

Eligibility Criteria:
Key inclusion criteria:~PK Phase: To be considered eligible to participate in this study, all of the following requirements must be met:~* Participants with histologically or cytologically confirmed diagnosis of metastatic or locally advanced solid tumors that have failed to respond to standard therapy, has progressed despite standard therapy, or for which no standard therapy exists, and who may benefit from treatment with a poly (adenosine diphosphate-ribose) polymerase (PARP) inhibitor as assessed by the Investigator.~* Eastern Cooperative Oncology Group (ECOG) performance status of 0 to 2.~* Adequate organ function as defined: Absolute neutrophil count ≥ 1,500 per microliter (/μL) (For Stage 3: \>=1000/μL); Platelets ≥ 100,000/μL; Hemoglobin ≥ 9 grams per deciliter (g/dL) (5.6 millimolar \[mM\]); Serum creatinine ≤ 1.5 × the upper limit of normal (ULN) or a calculated creatinine clearance ≥ 60 milliliters per minute (mL/min) using the Cockcroft-Gault equation or 24-hour urine creatinine clearance.; Total bilirubin ≤ 1.5 × ULN except in participants with Gilbert's syndrome. Participants with Gilbert's syndrome may enroll if direct bilirubin ≤ 1.5 × ULN of the direct bilirubin; Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) ≤ 2.5 × ULN unless liver metastases are present, in which case, they must be ≤ 5 × ULN.~* Participant has recovered to Grade 1 toxicity from prior cancer therapy (a participant with Grade 2 neuropathy or Grade 2 alopecia is an exception to this criterion and may qualify for this study).~* Female participant of childbearing potential is not breastfeeding, has a negative serum pregnancy test within 72 hours prior to taking study drug and agrees to abstain from activities that could result in pregnancy from Screening through 180 days after the last dose of study drug.~* Male participant agrees to use an adequate method of contraception and not donate sperm starting with the first dose of study drug through 90 days after the last dose of study drug.~* (For Stage 3): CNS inclusion - Based on screening brain magnetic resonance imaging indicating no evidence of brain metastasis or needing immediate local therapy.~* Participant is able to eat a high fat meal.~* Participant is able to fast for a minimum of 10 hours before start of visit and for an additional 4 hours after study visit.~Extension Phase:~* ECOG performance status of 0 to 2.~* Adequate organ function as defined: Absolute neutrophil count ≥ 1,500/μL (For Stage 3: \>=1000/μL); Platelets ≥ 100,000/μL; Hemoglobin ≥ 9 g/dL (5.6 mM); serum creatinine ≤ 1.5 × the ULN or a calculated creatinine clearance ≥ 60 mL/min (For Stage 3: ≥ 30 mL/min) using the Cockcroft-Gault equation or 24-hour urine creatinine clearance; Total bilirubin ≤ 1.5 × ULN except in participant with Gilbert's syndrome. Participants with Gilbert's syndrome may enroll if direct bilirubin ≤ 1.5 × ULN of the direct bilirubin; AST and ALT ≤ 2.5 × ULN unless liver metastases are present, in which case, they must be ≤5 × ULN~* Female participant of childbearing potential is not breastfeeding, has a negative serum pregnancy test within 72 hours prior to taking study drug and agrees to abstain from activities that could result in pregnancy from Screening through 180 days after the last dose of study drug.~* Male participant agrees to use an adequate method of contraception and not donate sperm starting with the first dose of study drug through 90 days after the last dose of study drug.~Key Exclusion Criteria: PK Phase:~* Known diagnosis of immunodeficiency~* Symptomatic uncontrolled brain or leptomeningeal metastases.~* Major surgery within 3 weeks of starting the study or participant has not recovered from any effects of any major surgery.~* Participant is considered a poor medical risk due to a serious, uncontrolled medical disorder; nonmalignant systemic disease; or active, uncontrolled infection.~* Known history of myelodysplastic syndrome or acute myeloid leukemia.~* Participant is currently taking any of the following P-glycoprotein (P-gp) inhibitors: amiodarone, azithromycin, captopril, carvedilol, clarithromycin, conivaptan, cyclosporine, diltiazem, dronedarone, erythromycin, felodipine, itraconazole, ketoconazole, lopinavir and ritonavir, quercetin, quinidine, ranolazine, ticagrelor, and verapamil (Does not apply for Extension Phase).~* Participant taking proton pump inhibitors, antacids, or histamine 2 blockers within 48 hours prior to study drug administration (Does not apply for Extension Phase).~* Participant has gastric, gastro-esophageal or esophageal cancer; participant is unable to swallow orally administered medication; or participant has gastrointestinal disorders or significant gastrointestinal resection likely to interfere with the absorption of niraparib.~* Participant has known active hepatic disease~* Participant has a past or current history of chronic alcohol use.~* Participant has significant pleural effusion or ascites that is expected to require drainage during the PK Phase (Does not apply for Extension Phase).~* For Stage 3 only: Participant is currently taking a lipase inhibitor or cholesterol absorption inhibitor, such as orlistat or ezetimibe, respectively. (Does not apply for participation in Extension Phase of this study).

- Gender: ALL
- Minimum Age: 18 Years
- Maximum Age: None
- Healthy Volunteers: f

Study Arms:
- Stage 1: Tablet-Capsule Sequence (Type: EXPERIMENTAL): Single dose niraparib tablet followed by single dose niraparib capsule followed by optional daily dosing extension phase
- Stage 1: Capsule-Tablet Sequence (Type: EXPERIMENTAL): Single dose niraparib capsule followed by single dose niraparib tablet followed by optional daily dosing extension phase
- Stage 2: Tablet-Capsule Sequence (Type: EXPERIMENTAL): Single dose niraparib tablet followed by single dose niraparib capsule followed by optional daily dosing extension phase.
- Stage 2: Capsule-Tablet Sequence (Type: EXPERIMENTAL): Single dose niraparib capsule followed by single dose niraparib tablet followed by optional daily dosing extension phase
- Stage 3: High fat meal-fasted sequence (Type: EXPERIMENTAL): Single dose niraparib tablet with a high fat meal followed by single dose of niraparib tablet in a fasted state.
- Stage 3: Fasted-high fat meal sequence (Type: EXPERIMENTAL): Single dose niraparib tablet in a fasted state followed by single dose Niraparib tablet with a high fat meal.

Based on this trial design, predict the completion outcome and termination type (if applicable).