Please assess the completion status of the following clinical trial:

Trial Title: Pain, Opioids and Pro-Inflammatory Immune Responses

Study Design Characteristics:
- Allocation: RANDOMIZED
- Intervention Model: FACTORIAL
- Observational Model: None
- Primary Purpose: BASIC_SCIENCE
- Time Perspective: None
- Masking: NONE
- Phase: PHASE1
- Number of Arms: 3.0

Eligibility Criteria:
Inclusion criteria:~* male and non-pregnant female, non-smoking adults in good general health~* between the ages of 21-40 years old~* fluent in English with willingness to participate in the research study~Supplementary Inclusion Criteria: Prescription Opioid Abusers~* DSM-IVR diagnosis of prescription opioid abuse or dependence disorder~* compliance in treatment and on a stable dose of buprenorphine (6-24mg/day) x at least 10 days prior to screening~* Participation in an ISAP treatment program or a qualified community-based opioid treatment program or private clinic for the entire duration of their study participation~Exclusion criteria:~* regular use of any medication that influences immune status or immune system function~* regular use of a medication that influences pain perception, including opioids (\* only for healthy subjects population\*)~* Regular use of a medication that influences pain perception, except for buprenorphine (\*\* only for POA population\*\*)~* known hypersensitivity to opioids or no previous opioid exposure (\*only healthy controls)~* presence of acute or chronic pain syndrome~* neuropsychiatric illness (i.e., peripheral neuropathy, schizophrenia) known to affect pain perception~* presence of chronic immune compromise (hepatitis C, HIV) or acute infection within the last four weeks~* current or past history of high blood pressure, heart disease, or stroke, or currently have a pacemaker.~* current DSM-IV diagnosis~* BMI less than 18.5 or greater than 29.9~* History of sleep apnea

- Gender: ALL
- Minimum Age: 21 Years
- Maximum Age: 40 Years
- Healthy Volunteers: t

Study Arms:
- Pain Challenge (Type: ACTIVE_COMPARATOR): Cold pressor test
- Pain + Opioid Challenge (Type: ACTIVE_COMPARATOR): IV fentanyl 1mcg/kg followed by cold pressor test
- Opioid Challenge (Type: ACTIVE_COMPARATOR): Administration of fentanyl 1mcg/kg of subject weight

Based on this trial design, predict the completion outcome and termination type (if applicable).