Please assess the completion status of the following clinical trial:

Trial Title: Macrolide Azithromycin to Prevent Rapid Worsening of Symptoms Associated With Chronic Obstructive Pulmonary Disease

Study Design Characteristics:
- Allocation: RANDOMIZED
- Intervention Model: PARALLEL
- Observational Model: None
- Primary Purpose: PREVENTION
- Time Perspective: None
- Masking: TRIPLE
- Phase: None
- Number of Arms: 2.0

Eligibility Criteria:
Inclusion Criteria:~* Clinical diagnosis of at least moderate Chronic Obstructive Pulmonary Disease (COPD), as defined by the following Global Initiative for COPD (GOLD) criteria:~  1. Post-bronchodilator forced expiratory volume in one second (FEV1)/forced vital capacity (FVC) ratio of less than 70%~ 2. Post-bronchodilator FEV1 less than 80% predicted, with or without chronic symptoms~* Cigarette consumption of 10 pack-years or more (may or may not be active smokers)~* Meets one or more of the following four conditions:~  1. Current, or history of, supplemental O2 use~ 2. Received a course of systemic corticosteroids for respiratory problems within 1 year prior to study entry~ 3. Visited an emergency department for a COPD exacerbation within 1 year prior to study entry~ 4. Hospitalized for a COPD exacerbation within 1 year prior to study entry~* Willing to make return visits~* Available by telephone for duration of study~* Minimum of 4 weeks from the most recent acute exacerbation (have not received a course of systemic corticosteroids, an increased dose of chronically administered systemic corticosteroids, and/or antibiotics for an acute exacerbation for a minimum of 4 weeks from the time of study entry)~Exclusion Criteria:~* Diagnosis of asthma~* Diagnosis other than COPD that results in the patient being either medically unstable, or having a predicted life expectancy less than 3 years~* Special patient groups (i.e., prisoners, pregnant women, or institutionalized patients)~* Women who are at risk of becoming pregnant during the study (pre-menopausal) and who refuse to use acceptable birth control (i.e., hormone-based oral or barrier contraceptive) for the duration of the study~* History of hypersensitivity to any macrolide antibiotic~* Taking any of the following medications:~  1. Cisapride~ 2. Ergot derivatives~ 3. Pimozide~ 4. Disopyramide~ 5. Cyclosporin~ 6. Tacrolimus~ 7. Nelfinavir~ 8. Bromocriptine~ 9. Hexobarbital~* Corrected QT interval (QTc) on electrocardiogram exceeding 440 ms~* Taking rifabutin or rifampin~* Chronic hepatic insufficiency~* Chronic renal insufficiency~* Diagnosis of bronchiectasis (defined as production of greater than one-half cup of purulent sputum/day)~* If, for either ear, formal audiometric testing in a sound booth results in a pure tone average (i.e., the average of the thresholds for the 4 frequencies 1000, 2000, 3000, or 4000) exceeding 50 decibel (dB), or if the threshold at any one frequency exceeds 60 dB, then the participant will be counseled by the audiologist concerning hearing aids and/or referral to an otolaryngologist. In addition, the audiologist may discuss with the participant whether or not to continue in the study. Following the examination and counseling, the participant will also discuss whether or not to continue in the study with one of the study investigators. If it is found that a participant's pure tone average in the two ears differs by more than 15 dB, or if the difference in the two ears for any one frequency exceeds 20 dB, then the participant will not be eligible for randomization into the study unless cleared by an otolaryngologist

- Gender: ALL
- Minimum Age: 40 Years
- Maximum Age: None
- Healthy Volunteers: f

Study Arms:
- Azithromycin, 250 mg (Type: ACTIVE_COMPARATOR): Macrolide Antibiotic (Azithromycin)
- Placebo (Type: PLACEBO_COMPARATOR): Inactive

Based on this trial design, predict the completion outcome and termination type (if applicable).