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Radioligand Therapy for Prostate Cancer
Negotiable Min Order Quantity Unit
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- South Korea
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|Keyword||prostate , medicine & drugs||Unit Size||-|
|Brand name||PSMA-DGUL||Unit Weigh||-|
|Supply type||Available||HS code||-|
Lu-177 DGUL is a radiopharmaceutical agent specifically designed to target and treat prostate cancer cells by exploiting the overexpression of the prostate-specific membrane antigen (PSMA) on their surface. PSMA, a type II transmembrane glycoprotein, is predominantly found in prostate cancer cells, while its presence in normal tissues is relatively limited. This differential expression makes PSMA an attractive target for the development of targeted therapies, such as Lu-177-DGUL, for prostate cancer.
Lu-177-DGUL is comprised of three essential components: the novel DGUL molecule, a linker, and the radionuclide Lutetium-177 (Lu-177).
The DGUL molecule serves as a targeting moiety, selectively binding to PSMA with high affinity. This selective binding ensures that the radiopharmaceutical agent primarily targets prostate cancer cells while sparing healthy cells.
The linker is a chemical component that connects the DGUL molecule to the radionuclide, Lu-177. The linker plays a vital role in maintaining the stability of the radiolabeled compound and ensuring that the radionuclide remains attached to the targeting moiety until it reaches the desired site of action. The choice of an appropriate linker is essential, as it can influence the pharmacokinetics, biodistribution, and efficacy of the radiopharmaceutical.
Lu-177, a radioactive isotope of Lutetium, is chosen as the radionuclide for Lu-177-DGUL due to its favorable properties. It emits beta particles, which have a relatively short range and moderate energy, allowing them to cause DNA damage and cell death in the targeted cancer cells. Moreover, Lu-177 has a half-life of approximately 6.7 days, which provides sufficient time for the radiopharmaceutical agent to localize in the tumor and exert its therapeutic effect.
The design of Lu-177-DGUL ensures rapid secretion from the body, reducing the duration of exposure to radiation and minimizing potential toxicities and side effects. This is particularly important for patients who may be more sensitive to radiation, such as the elderly or those with pre-existing medical conditions.
Upon administration, Lu-177-DGUL circulates through the bloodstream and selectively binds to PSMA on the surface of prostate cancer cells. The radiolabeled compound is then internalized, and the Lu-177 emits beta radiation, causing DNA damage and subsequent cell death. This targeted approach enables a more precise and effective treatment, minimizing damage to healthy tissue and reducing the side effects commonly associated with traditional cancer therapies such as chemotherapy and radiation therapy.
DGUL, a novel radiopharmaceutical agent, is specifically designed to target and treat prostate cancer cells by exploiting their overexpression of the prostate-specific membrane antigen (PSMA). PSMA is a type II transmembrane glycoprotein that is highly overexpressed on the surface of prostate cancer cells, while its expression in normal tissues is limited. This characteristic makes PSMA an ideal target for the development of targeted therapies for prostate cancer.
DGUL consists of three main components: a targeting moiety, a linker, and a radionuclide. The targeting moiety is a small molecule or peptide that specifically binds to PSMA with high affinity. This selective binding ensures that the radiopharmaceutical agent primarily targets prostate cancer cells, leaving healthy cells largely unaffected.
The linker is a chemical component that connects the targeting moiety to the radionuclide. It plays a crucial role in maintaining the stability of the radiolabeled compound and ensuring that the radionuclide remains attached to the targeting moiety until it reaches the desired site of action. The choice of an appropriate linker is essential, as it can affect the pharmacokinetics, biodistribution, and efficacy of the radiopharmaceutical.
The radionuclide is the radioactive component of DGUL that emits radiation upon decay, ultimately causing DNA damage and cell death in the targeted cancer cells. Two common radionuclides used in DGUL are Lutetium-177 (Lu-177) and Actinium-225 (Ac-225). Lu-177 emits beta particles, which have a relatively short range, whereas Ac-225 emits alpha particles, which possess higher energy and can cause greater DNA damage. The choice of radionuclide depends on the specific clinical application and desired treatment outcomes.
Upon administration, DGUL travels through the bloodstream and selectively binds to PSMA on the surface of prostate cancer cells. Once bound, the radiolabeled compound is internalized into the cancer cell, where the radionuclide emits radiation that causes DNA damage, ultimately leading to cell death. This targeted approach allows for a more precise and effective treatment, minimizing damage to healthy tissue and reducing the side effects commonly associated with traditional cancer therapies such as chemotherapy and radiation therapy.
DGUL has shown promise in clinical trials as a targeted therapy for patients with advanced, metastatic, or treatment-resistant prostate cancer. Its ability to deliver a potent dose of radiation directly to cancer cells while sparing healthy tissue makes it an attractive option for patients who have exhausted other treatment options or who are not candidates for surgery or radiation therapy.
In conclusion, DGUL represents a promising targeted approach to treating prostate cancer. By selectively targeting PSMA overexpressed on cancer cells, DGUL minimizes damage to healthy tissue, potentially reducing side effects and improving the quality of life for patients undergoing cancer treatment. The combination of a targeting moiety, linker, and radionuclide allows for the precise delivery of radiation to cancer cells, ultimately leading to DNA damage and cell death. As research continues, it is hoped that DGUL and similar targeted radiopharmaceuticals will offer new therapeutic options for patients with prostate cancer and other malignancies.
DGUL, a novel radioligand therapy, has been specifically designed to offer enhanced selectivity for Prostate-Specific Membrane Antigen (PSMA), a transmembrane protein that is highly expressed in prostate cancer cells. This high degree of selectivity ensures accurate targeting of prostate cancer cells, while minimizing damage to healthy cells. DGUL's unique properties are crucial in addressing the significant unmet medical needs of patients suffering from metastatic castration-resistant prostate cancer (mCRPC), a highly aggressive form of the disease that currently has limited treatment options.
One of the notable features of DGUL is its rapid renal excretion, which effectively reduces the side effects associated with unbound radioligand agents. This is particularly important because the accumulation of unbound radioligand agents in healthy tissues can lead to significant toxicity and adverse effects. By promoting rapid clearance of the unbound agents from the body, DGUL minimizes the potential harm to non-target tissues and maximizes patient safety.
The accelerated renal excretion of DGUL also allows for the administration of higher millicurie (mCi) doses of Lutetium-177 (Lu-177), a radioisotope commonly used in radioligand therapy. The higher doses of Lu-177 are believed to potentially increase the therapeutic efficacy of the treatment by delivering a more potent radiation dose to the targeted cancer cells. This increased potency may result in better tumor control and improved clinical outcomes for patients.
DGUL has recently demonstrated promising results in Phase 2 clinical trials, showcasing its potential to be a highly effective treatment option for patients with mCRPC. The positive outcomes from these trials have led to the orphan drug designation for DGUL in Korea, which highlights the importance of this novel therapy in addressing unmet medical needs in the field of prostate cancer treatment.
The orphan drug designation for DGUL in Korea is a significant milestone, as it provides various benefits such as faster regulatory approvals, reduced fees, and market exclusivity. This designation is expected to accelerate the development and commercialization of DGUL, ultimately benefiting patients suffering from mCRPC who currently have limited treatment options.
In summary, DGUL is a promising radioligand therapy that combines enhanced selectivity for PSMA with rapid renal excretion to minimize side effects and maximize patient safety. The positive Phase 2 clinical trial results and orphan drug designation in Korea underscore its potential to address the unmet medical needs of patients with mCRPC. By enabling the administration of higher mCi of Lu-177, DGUL may offer improved therapeutic efficacy and clinical outcomes for patients suffering from this aggressive form of prostate cancer.
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By Melisa Cavcic Equinor has received consent from Norway’s regulator to use a Transocean-owned rig for well intervention on a field located in the North Sea.
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Beijing Yuexin times Technology Co., Ltd. (Stock Code: 838737), founded in 2003, was listed in the National SME share transfer system (new third board) in 2016. It is headquartered in Zhongguancun, Beijing. It has one wholly-owned subsidiary and three offices (Shanghai, Nanjing and Chengdu). The registered capital is 55 million yuan. More than 100 employees. High tech enterprise, ITSS cloud computing service capability standard (Level 3), CMMI3 software maturity (Level 3), Beijing "specialized, special and new" small and medium-sized enterprises.
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This holiday season, the highly-anticipated new docudrama "Joan of Arc" will air on BYUtv and will provide viewers an in-depth look at the amazing story of the unlikely French heroine.
Airing on Thanksgiving, November 26 at 6 PM MT with rebroadcasts throughout the holiday season, "Joan of Arc" is told through the eyes of the young woman and provides dramatized scenes of her life and interviews with scholars and experts.
"This story is told by people of faith who understand Joan's spiritual experiences and who appreciate them and don't try to minimize them and explain them away," Russell Holt, the Emmy-award winning documentary filmmaker who directed and co-produced "Joan of Arc" told the Gospel Herald in an exclusive interview.
"We embraced Joan's spirituality and the powerful spiritual experiences she had as a girl, and portrayed those experiences in the most accurate and spiritual way that they've ever been portrayed in any telling of her life."
Filmed in France, the docudrama uses the actual 15th-century records of Joan's trial for heresy and testimony from those who knew her to bring truly her story to life.
"I went back to the original 15th century documents for Joan's court trials, which are lengthy and very detailed," Holt revealed. "Because of these court documents, we probably know more about Joan of Arc than anybody in Medieval times. Going through these documents, one finds Joan in there - things she said, verbatim. It was actually kind of a spiritual experience to read her actual words and how she responded to this intense investigation during these moving trials. Her faith and courage comes through very clearly, as does the fact that she was inspired by God."
Joan's story is undeniably one of tremendous faith and courage: At just thirteen years old in 1425, she experienced a series of angelic encounters. Despite having no military training, the humble farm girl obeyed the angel's commands and embarked on a seemingly impossible mission - to oust the occupying English from France and clear the way for a new king to be crowned.
"We didn't minimize Joan's spiritual experience or go past it to other things that would be more interesting to a secular audience," Holt said. "We show that experience and the impact that it had on the rest of Joan's life and ultimately, France."
While many historians and scholars have discounted Joan's spiritual experience as mental illness, Holt says he has no doubt the young woman was divinely inspired - in fact, studying her story strengthened his own faith in an incredible way.
"For those who love and revere the Bible, Joan's experiences ring true and are very meaningful," he explained. "Her spiritual experiences are reminiscent of many of the calls from God that came through the ages of the Bible in the Old and New Testaments. You think about Mary in the New Testament times receiving a visit from a heavenly messenger from God, Gabriel, calling her to a divine mission, and how her faith in accepting that mission literally changed the world."
After leading the French to a momentous victory, Joan was captured, tried for witchcraft and heresy and burned at the stake in 1431 at the age of 19 - ultimately sacrificing her life for her obedience to God.
"Even the most unlikely people who are touched by God can do incredible things and change the world," Holt said. "That's Joan's story. She was an impoverished peasant girl living on her father's farm when God entered into her life and transformed her by giving her this mission. I just love the fact that such an underdog, such an unlikely person can be used by God for His purposes."
Joan of Arc was officially canonized in 1920, and to this day is seen not only as an enduring symbol of French unity, but an example of steadfast personal honor, faith and courage.
"I hope that young people, particularly young women will see a very powerful role model in Joan," Holt said. "Young people today don't have a lot of true life heros and heroines to look up to and model their lives after. Joan's not a fictional character, she's real. And I hope that young woman can look at her life and the way she, even as a teenager, courageously followed God at all costs and eventually gave her life at the age of 19. That's an inspiring story for young people on how important it is to follow God in your life."
Tune in to BYUtv on Thanksgiving, November 26 at 6 PM MT for the highly anticipated look at illustrious Joan of Arc.

domain: christianity


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A mother's love for her child is like nothing else in the world. It knows no law, no pity. It dares all things and crushes down remorselessly all that stands in its path.
Before they were ever born, my children saved my life.
When I go back in time and retrieve my memories from 35 years prior, the ‘day in May’ comes into focus. If you remember my story, I was miraculously rescued from a particularly violent afternoon by ‘Steel Magnolia’, a white-haired mother figure in my life who harbored me in her home for three days. (Un)incredible Hulk had nearly killed me that day and had certainly shattered and fractured my emotional insides.
Steel Magnolia was the triage in the aftermath of a life-altering experience. Soon, she put me on a plane to be greeted by North Star, my earthly mother.
My story of intimate partner violence reads like a textbook. There are stereotypes in life because people fit them often enough to be considered, well…stereotypical. You might say I fit the mold. I met the statistical criteria. If one was doing a scientific study on domestic violence, I was the evidence base to prove the hypothesis. In a sort of rehearsed dance, the cycle of abuse kept happening and I was numb to its affects.
Angst. Incident. Apology. Honeymoon. Angst. Incident. Apology. Honeymoon. Irritations. Aggravations. All wrong in every way. Recycle old fights. Make up new ones. Yell, scream, kick, punch, cuss, spit, strangle. Cry. Apologize. Honeymoon.
‘Incident’ sounds so innocuous. So virginal. So sterile and pleasantly non-violent.
For those 25% of us, it’s fresh every time we talk about it. It quickens our heart rate, and we still look for the bad guys (can often pick them out in a crowd); it was a big deal. Incident is code for the really bad stuff in a domestically violent relationship.
The National Coalition Against Domestic Violence offers statistics to be able to help you categorize the typical abuser, woman caught in a web of violence and many of the trends we wish to avoid, ignore or even choose not to see ourselves within them. Click here.
With that backdrop, it is a saying noteworthy and true: my children saved me.
I was 19 years old. Not pregnant. Not planning to be pregnant and yet my children saved me. One data point the stereotype didn’t figure into my experience was a fierce maternal instinct.
I come by my maternal instincts both by nurture and nature. Always intuitive, I learned early a sense of protection of those more vulnerable than myself. In high school, I rode a K-12th grade big yellow bus. The fifth-grade boys often got schooled by me when I caught them teasing and bullying kids younger than themselves. I was the oldest rider on that bus and I quickly became a School Marm of sorts— ruling the bullies with an iron fist. I had instincts. I held values that people shouldn’t be treated that way. I came on strong, yes, but the littlest kids loved me for it. The fifth graders — not so much.
Sadly, my instincts only served the underdog. Rarely, myself. When now at 19, I was the more vulnerable and less powerful party in a violent relationship, I thought myself to be invincible and fully capable to handle the beatings, the emotional onslaught; the circuitous path I was on— that looked more like a stereotypical cycle of abuse chart.
I thought I could handle it.
I thought I wanted to handle it.
I thought I loved him.
I thought he would change.
I certainly had no instincts of self-protection.
I certainly lacked a propensity to self-worth.
The day of my flight, I returned to my college dorm room to gather a few belongings to cram into a suitcase for the plane ride home. The rest, I would be leaving behind.
Un(incredible) Hulk had kept a thumb on where I was over that time frame of being harbored at Steel Magnolia’s home. He stalked me and staked me out so that when I went onto campus, walking up the lane to my cottage, he arrived. He pulled up in his little orange Pinto— to this day I despise pintos.
He pulled up beside me, windows down.
His mouth was running as much as the car engine.
It’s hard to explain to an audience who hasn’t experienced this kind of abuse the dynamics at play. If you have experienced it, you’ll probably be able to finish my sentences. Sappy apologies began the tirade of verbiage. Joking with me; trying to make me laugh. Certainly, feigning concern and sorrow at our abrupt and near imminent break up. Coaxing me to run away with him and leave it all behind. Promising a better life over the horizon, at the beach, in the mountains; over the rainbow. Asking for my whereabouts and my plans— reminding me we had a wedding planned, and future children named. Nearly begging me with false words of love and tears. ‘It’ was deep, if you know what I mean.
It’s as though he sat perched on my left shoulder like a taunting devil— my cousin, Secret Keeper— angel in disguise, on the other. She had driven me to campus and was watching the spectacle of me being lured back. Just three days prior, he had almost killed me. And there I was, riding on his fender, passenger car door open, living fast & free, hair blowing in the wind, his car gaining speed, laughing; listening to his excuses and his dreams to cart me away to a better life on minimum wage and a pinto for our ride. Promising my love, asking him to get better so we could be together. It runs through my mind like a major motion picture-- but neither of us were acting. This was real life.
Secret Keeper was anxious and on edge. She had seen this pattern in me more times than she could count. She was trying to be the School Marm, but I was a willing punching bag— a gullible soul— willing to relinquish all of myself for him, willing to sacrifice all of my dignity to him and willing to compromise my body and it’s safety because of him.
In one of the only good and sensible decisions I made for myself at age 19, something snapped. I knew I would not be running away with him. I knew I would not walk down an aisle toward him. I knew I would not bear his children or reside in near proximity to him. I would get on a plane for home and start toward the journey of healing and here’s why:
Maternal instincts, plain and simple.
in·stinct [instinct] NOUN
instinct (noun) · instincts (plural noun)
1. an innate, typically fixed pattern of behavior in animals in response to certain stimuli:
a natural or intuitive way of acting or thinking:
a natural propensity or skill of a specified kind:
the fact or quality of possessing innate behavior patterns:
1. imbued or filled with (a quality, especially a desirable one):
Before they were ever born, my children saved me.
I didn’t make a decision to leave my abusive fiancée for myself. I was never that strong. I never had the self-worth to believe I deserved more. I never thought I could not get along with 'that' for the rest of my life— though in my heartest of hearts I prayed to be released from it all.
The thing that empowered me was this: my children. The well-being and the fierce protection of my children was the only definitive and determining factor that I am no longer in an intimately violent relationship with Un(incredible) Hulk.
I looked at him square in the eyes— or over my left shoulder, as it were — and said,
“I don’t care what you do to me. I can handle it. But I will not let you do this to my kids. If you treat me this way, you will treat my kids this way and I cannot live with that. I will not let that happen.”
I jumped off the car fender, slammed the car door and stood in the middle of the street while he drove away. I sobbed. I would have stayed. I made a decision for my future babies.
My maternal instinct won the day. My mother bear already had claws and bared her teeth. I would take a bullet for my children, but I would not let my children take bullets for me because my esteem and my self-worth were so tanked and in the sewage of domestic violence. Just because I was tolerant to be a punching bag, my kids were not going to suffer that life as well. (see statistics here) "An earlier study found that approximately 35 percent of children in the United States between the ages of 14 and 17 have been exposed to intimate partner violence and that 40 percent of all child abuse victims report violence in the home between their parents (Finkelhor et al., 2009).
I’ve recently contemplated the first part of my last words to (Un)incredible Hulk. ‘I don’t care what you do to me’ — what angst that must have caused my Secret Keeper. What sorrow it must have brought my own mother that I valued her very flesh and blood — her youngest child— so little. How blind those who DID love and care for me must have thought me to be that I wouldn't run from danger and see my own worth. To them, I'm sorry. A million times over, I'm sorry.
Why did it take the potential and probable harm to my future children for me to end the relationship that pounded me with pain upon pain? Why couldn’t I see that I was someone else’s gift and joy? That I lived as someone else’s 'I love you to the moon and back' or 'I’m over the moon about you' and 'let me lasso the moon for you' kind of girl?
I think I’m still answering that question. A belief in one’s own worth and intrinsic value sometimes takes a lifetime.
But I never have, nor will I ever regret, or feel less in debt,
that my children saved me.
My deep love for them began so long ago. My deep love for them was the only stream of courage to bubble up from my soul when faced with a future of violence.
I think that’s why motherhood has always been this absolute sacred trust to me, this mystery of life upon life — this give and take of salvation and protection and intuition and sheer maternal instinct.
The day in May almost killed me.
Mother’s Day gave me my life back. To some, it might be a Hallmark holiday.
For me, this 'day in May', saved me.
To my four daughters, thank you.
Before I ever knew you, you reached across time and gave me the courage I needed. You were fearfully and wonderfully made.
Several years ago, my first son-in-law was coaching another son-in-law coming into the culture of our family. He simply said of me, "Don't poke the bear." I don't think anyone realized how high a compliment I took that simple piece of advice. Because for me, it echoed back to a conversation I had on the fender of a pinto a very long time ago. It hearkened me to remember my better, rather, by very best instincts.
My intuition runs deep. My maternal instincts give me the deepest love for my children--and that love saved my life.
Don't poke the bear!

domain: psychology


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September 2 - September 10, 2019
“All of a sudden,” the artist writes, “I realized that we all were like bowls. Whatever the shape, we are all precious and deserve to be filled in.” – Sun Choe
Sun Choe uses a strictly minimalist color palette to concentrate upon the form and essence of a single object, such as a bowl, house, and candle. By repeatedly painting these forms in sketch-like strokes, Choe obtains a transcendent state of religious discovery.
At first glance, Sun Choe’s painting Pray (2014) appears to hold up to the serene and contemplative image suggested by its title. Yet a closer glance reveals a clutter of broad brushstrokes, a rough-hewn canvas, and hazy boundaries between the outline of the depicted bowl and its background. The painting is analogous to the act of prayer itself, where a calm exterior belies the storms of thought and concentration swirling beneath.
Point of Time (2018) follows a lineage of artists inspired by the Korean moon jar’s uniquely rotund shape. Criss-crossing lines slash through the painting, imbuing the jar with an uneasy energy and creating a compelling tension between negative and positive space on the canvas.
Galerie Pici Seoul Level 1

domain: painting


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However, there may be quick relief to assist deal with the pain till you will get to the dentist. We have more details about emergency dental care prices and a finance calculator on our fees web page. It was an army dentist who didn’t imagine me once I instructed him the Novocaine had not labored. Although dental procedures might be anxiety scary, sedation dentistry is a rapidly increasing option for many which supplies quite a lot of profit; however, it is crucial to concentrate on the dangers as loss of life from a easy go to to the dentist can occur.
I was reading one other thread about Frogdropping had gone to the dentist and it is too previous to reply. It’s particularly essential to understand the difference between the 2 when you expertise a dental emergency over the weekend or at night time time when dental workplaces are typically closed. Watch whether the dentist extends to you with all the right remedies or by no means. Its true emergency dental clinics in Scottsdale are all the time there to help, but negligence always costs greater than a routine checkup, and it not only takes your value but also gives you immense toothache.
If reinsertion will not be attainable, hold the tooth beneath the tongue and go to the dentist immediately. In fact he strongly really helpful that I see a dentist which I might have finished initially if I may have afforded it to begin with. Remember that complications normally lead to bills, so be sure you have spoken to your insurance coverage company previous to visiting the dentist. In case you have an oral infection that is at a essential level, which means you’re having bother breathing, swallowing, or your throat has major swelling, overlook about calling an emergency dentist and call 911 immediately.

domain: health


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On the basis of the traditional multi-cylinder hydraulic cone broken main shaft fixed, eccentric sleeve rotating structure and lamination crushing principle, the HPT multi-cylinder hydraulic cone crusher structure has been optimized through breakthroughs, which has significantly improved the performance And the crushing capacity; and the supporting design of the hydraulic lubrication system to ensure that the equipment operates more intelligently and reliably.
C6X jaw crusher equipment structure, use function and production efficiency and other indicators reflect the modern advanced technology level, which solves the problems of low production efficiency and difficult installation and maintenance of existing jaw crushers on the market. It is an ideal rough Crushing equipment.
The vertical mill is a new type of ultra-fine grinding equipment independently designed by our company based on ordinary vertical mills based on ordinary vertical mills, using current advanced Taiwan grinding roller technology and German powder selection technology. The vertical mill integrates ultra-fine grinding, grading and conveying, and is an ultra-fine milling equipment with excellent performance.
Our company has developed the fifth-generation pendulum suspended roller mill with several inventions and technologies-MB5X series pendulous suspended roller mill based on the accumulation of more than thirty years of on-site field test data and experimental analysis. It represents today's advanced cantilever milling technology, and is suitable for all kinds of non-flammable and explosive brittle ores with Mohs hardness below 7 and water content below 6%.
In response to the increasing demand for large-scale, intensive, energy-saving and environmental protection, and high-quality machine-made sand in the sand and gravel market, our group has further optimized and designed the structure and function of impact breaking on the basis of thousands of impact breaking sand shaping applications A new generation of high efficiency and low cost sand making and shaping equipment --- VSI6X series vertical shaft impact crusher (also known as sand making machine).
What does our EPC project package refer to?
EPC is the general contracting of the project, also known as "turnkey project". This model is widely used in the field of engineering construction. .
We configure one-to-one project managers for each project, provide professional project management services, and implement strict schedule management for each project stage to ensure that the project is completed on schedule. Strict internal production management ensures that production is completed on schedule. Provide customers with a complete construction schedule and recommendations to allow production line construction to be completed as scheduled


Storage Technologies and Systems
Intro.: The storage system is an important part of the computer system and plays a vital role in the performance of the entire system. The storage wall is more and more severe especially in the era of big data. With the continuous rising of storage demands and the booming of new storage device technology, the new computer architecture with characteristics of computing and storage merging and storage systems based on NVM devices become our focus.
Storage Technologies and Systems Institute, also the data storage system key laboratory of the Ministry of Education of China and the Education Ministry’s Engineering Research Center for Data Storage Systems and Technology, has over 40 faculty members including 2 Chang Jiang Chair scholars, 2 Chang Jiang scholars, and 2 “Talent of the New Century” scholars. With over 40 years of history in data storage research since 1974, our institute is the nation’s key research and educational center in storage system and architecture area. Recent accomplishments of our institute include winning over 40 research contracts and grants such as 973, 863, NSFC Key projects, regular projects, etc, cultivating many high quality graduate students, receiving many national/provincial research awards, entering the finalist of international storage challenge of SC06, publishing over 500 technical papers and filing over 120 patents.
Contact: Prof. Fang Wang, firstname.lastname@example.org
|C||Cao Qiang||Chen Jia Zhong||Chen Jian Xi||Chen Jin Cai|
|F||Fan Ye Bin||Feng Dan|
|G||Guo Hong Xing|
|H||Hu Di Qing||Hu Yu Chong||Hua Yu||Huang Jian Zhong|
|L||Li Chun Hua||Li Guo Kuan||Li Jie Qiong||Li Rong||Liu Shao Yun||Lu Ping|
|Q||Qin Lei Hua|
|S||Shi Zhan||Sun Wei Ping|
|T||Tan Zhi Peng||Tan Zhi Hu||Tong Wei|
|W||Wan Ji Guang||Wan Sheng Gang||Wang Fang||Wang Hai Wei||Wang Hua||Wu Fei|
|X||Xia Tao||Xiao Liang||Xie Yu Lai||Xie Chang Sheng||Xu Wei|
|Z||Zeng Ling Fang||Zhou Ke|


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Weather Forecast for Royal Oak, MI
Current Weather Conditions
S 13 mph
Conditions at Troy
Cloudy with periods of light rain. High 59F. Winds SSW at 10 to 20 mph. Chance of rain 60%.
A shower is possible early. Mostly cloudy skies early, then partly cloudy after midnight. Low 37F. Winds WSW at 5 to 10 mph.
Cloudy skies. High 42F. Winds W at 10 to 15 mph.
Mostly cloudy skies early, then partly cloudy after midnight. Low 29F. Winds NW at 5 to 10 mph.
Partly cloudy. High 39F. Winds WNW at 10 to 15 mph.
Mainly clear skies. Low 28F. Winds SW at 5 to 10 mph.
Sunshine along with some cloudy intervals. High 44F. Winds WSW at 10 to 15 mph.
Partly cloudy skies. Low 27F. Winds W at 5 to 10 mph.
Mainly sunny. High 39F. Winds W at 5 to 10 mph.
Mostly clear skies. Low 27F. Winds WSW at 5 to 10 mph.


Maidstone Borough Council has granted Gallagher Properties Ltd planning permission for a B1/B8 distribution warehouse development at Junction 6 of the M20 motorway.
Brooklyn Park will total 38,000 sq ft in one building, which can be sub-divided into smaller units. The units will be 9 metres high to eaves with ‘24/7’ access so are ideally suited for logistics and distribution companies.
The Council complemented Gallagher Properties on the pre-application consultation process and the scheme design, described as ‘exemplar’ during the meeting.
Head Office address:
Gallagher Group, Leitrim House, Little Preston
Aylesford, Kent ME20 7NS
Gallagher Aggregates Ltd., Hermitage Quarry
Hermitage Lane, Maidstone, Kent ME16 9NT


text:
Herrzeit by Adolf Herr Cuckoo Clock The Black Forest Saw M. AH 870/1 8TMT NEW
Herrzeit by Adolf Herr Cuckoo Clock – The Black Forest Saw Mill NEW Length: 55 cm/21.7 inch Width: 42 cm/16.5 inch Depth: 27 cm/10.6 inch This is a cuckoo clock with a traditional Black Forest Saw Mill. It has a shingled roof with a bell tower, a chimney, attic windows and wooden pine cones. The two mill workers saw the log in time to the cuckoo call, which is once on the half hour and on the full hour according to the time. Two alternating melodies – Edelweiss and Happy Wanderer – play every hour while the water wheel and the frame saw turn. Meanwhile the figurines wearing the Black Forest costume dance around to the music. His signature guarantees the experience of 7 generations of clock-workmanship. This clock comes with a certificate of authenticity (AHC). Clock Movement: 8-Day(weekly wind-up) Regula rack strike movement with night off. Clock-Face: HerrZeit Wooden dial, diameter 4 Inch (10 cm), with wooden hands. Dancing Figurines: Handcarved and handpainted wooden couples in Black Forest costume. Pendulum: HerrZeit bolt pendulum with fine adjustment. Musical Movement: Reuge musical movment (22 tones) with two different melodies (Edelweiß & The Happy Wanderer). Chime: Diameter 4,7 Inch (12cm), burnished Cuckoo-Bird: HerrZeit cuckoo bird (handcarved). Publication Year: 1999 Designer: Juergen Herr. Item#: AH 870/1 8TMT. On our about me Site you will find more information about us. This item is in the category “Home & Garden\Home Décor\Clocks\Wall Clocks”. The seller is “isdd-gmbh” and is located in this country: DE. This item can be shipped worldwide.
- Manufacturer: HerrZeit by Adolf Herr
- Brand: ISDD Cuckoo Clocks
- MPN: AH 870/1 8TMT
- Type: Cuckoo Clock
- EAN: 4260213891055

domain: artistic


text:
1. On the website it is indicated that "High resolution spectrum acquisition with up 1824 data points" , (1700 nm - 900 nm) / 1824 gives 0.44 nm resolution but in the test data indicated ~10 nm resolution. Could you please clarify?
2. Is it possible to capture spectrum of pulsed lasers with TIDA-00554?

domain: physics


III-4 Table 17: US Exports of Petroleum Resins, Coumarone, Indene
, Polyterpenes, Polysulphides in Primary Forms (2013 & 2014): Percentage Breakdown of Value Exports by Country of Destination (includes corresponding Graph/Chart) III-4 Table 18: US Imports of Petroleum Resins, Coumarone, Indene
, Polyterpenes, Polysulphides in Primary Forms (2013 & 2014): Percentage Breakdown of Value Imports by Country of Origin (includes corresponding Graph/Chart) III-5 Corporate Development.
Suction and SpE-lwageneinsEntze on the wastewater treatment plants (special structures and sewage treatment plants) of WVERDistribution in Area 4 lots Lot 1 - South: approximately 215 buildings in the municipalities Roetgen, Monschau, Heimbach, Schleiden, Hellenthal, Kall, Cute Home, Hurtgenwald and NideggenLot 2 - Ost: about 173 buildings in the municipalities DE-ren, Merzenich, Lower Trim, Noervenich, Kreuzau, Langerwehe, indene
, Eschweiler, Stolberg, Hurtgenwald and NideggenLot 3 - North: approximately 194 buildings in the municipalities Heinberg, GER, Wassenberg, forest wetlands, Ubach-Palenberg, Geilenkirchen, Linnich, Titz, JE-lich, Aldenhoven and BaesweilerLot 4 - West: approximately 122 buildings in the municipalities chen, Duke Rath, Wuerselen and Alsdorf.
Table 1--resin types used in the rubber industry Reactive resins Non-reactive resins Curing resins Reinforcing resins Tackifying resins Phenol-formaldehyde Phenol-formaldehyde Phenol-formaldehyde Resol type Novolak type Novolak type High styrene resins Hydrocarbon resins Methylene donors Terpene derivatives Resorcinol (formaldehyde) Coumarone indene
Polybutadiene Rosin derivatives Styrene-acrylonitrile Tall oil derivatives Polyvinyl chloride resins Phenol-acetylene condensation Table 2--tread formulation used for resin evaluation Reference Reference Resin Components (phr) + oil (phr) (phr) sSBR: 25% styrene, 42% vinyl, 6570.


Samsung Galaxy Note 20 and Note 20 Ultra in the US grabbed the latest software update via Verizon that supports eSIM. This update carries firmware number N981USQU2DUJ6 for Note 20 and N986USQU2DUJ6 for Note 20 Ultra.
This software update provides the latest security patch and support for BYOD (“bring your own device”) when making the switch to Verizon from select carriers. It also includes the new Dual SIM Dual Standby (DSDS) feature, which allows you to use two phone numbers on the same device.
If you’re not already on Verizon’s 5G Nationwide network, Galaxy Note20 users from other North American carriers will now be able to bring their device and instantly switch to Verizon. Just insert and activate a new Verizon SIM card in your Galaxy Note20 device and it will automatically adapt to the Verizon network and experiences.
Dual SIM Dual Standby (DSDS)
DSDS enables you to use two phone numbers on the same or different networks with Dual SIM support. Subscribers can register 1 physical SIM and 1 eSIM on their Galaxy Note20 device. You can send and receive calls and messages on either phone number. One mobile data network can be used at a time as DDS (Designated Data Subscription). You can set the primary SIM and default phone number in Settings > Connections.
Samsung Galaxy Note 20 mobile was launched on 5th August 2020. The phone comes with a 6.70-inch touchscreen display with a resolution of 1080×2400 pixels and an aspect ratio of 20:9. Samsung Galaxy Note 20 is powered by a 2.4GHz octa-core Samsung Exynos 990 processor that features 4 cores clocked at 2.4GHz and 4 cores clocked at 1.8GHz. It comes with 8GB of RAM. The Samsung Galaxy Note 20 runs Android 10 and is powered by a 4300mAh non-removable battery. The Samsung Galaxy Note 20 supports wireless charging, as well as proprietary fast charging.
As far as the cameras are concerned, the Samsung Galaxy Note 20 on the rear packs a 12-megapixel primary camera with an f/1.8 aperture and a pixel size of 1.8-micron; a 64-megapixel camera with an f/2.0 aperture and a pixel size of 0.8-micron, and a 12-megapixel camera with an f/2.2 aperture and a pixel size of 1.4-micron. The rear camera setup has autofocus. It sports a 10-megapixel camera on the front for selfies with an f/2.2 aperture and a pixel size of 1.22-micron. The front camera also features autofocus.
The Samsung Galaxy Note 20 runs One UI is based on Android 10 and packs 256GB of inbuilt storage that can be expanded via microSD card (up to 1000000GB). The Samsung Galaxy Note 20 measures 161.60 x 75.20 x 8.30mm (height x width x thickness) and weighs 192.00 grams. It was launched in Mystic Bronze, Mystic Gray, and Mystic Green colors. It features an IP68 rating for dust and water protection. It bears a glass body.
Connectivity options on the Samsung Galaxy Note 20 include Wi-Fi 802.11 a/b/g/n/ac/Yes, GPS, Bluetooth v5.00, NFC, and USB Type-C. Sensors on the phone include an accelerometer, ambient light sensor, barometer, compass/ magnetometer, gyroscope, proximity sensor, and in-display fingerprint sensor. The Samsung Galaxy Note 20 supports face unlock.
Recently, the Galaxy S21 lineup grabbed the same firmware update and now this time the Korean tech firm sending November 2021 patch update to its Note 20 owners. We don’t have an official changelog. The new software update is currently rolling out in the UK.
Galaxy Note 20
Galaxy Note 20 Ultra
Owners of the Galaxy Note 20 lineup can receive notification of this update. By chance you don’t receive an update notification then check the update manually by going to the device Settings >> Software updates >> Download and install.
Note: Before upgrading to the latest version make sure your smartphone is connected with a proper internet connection, we recommend you to download it over WIFI so that you will not face any error.


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Consider if everything in our universe has a vibration that could be measured…
Consider the vibrations of sound —music, noise, speech…
Consider how the vibrations of the sound of your name and your name itself can impact your life journey in our universe…
Considering all of that, how would you select a name for your child?
Numerology provides some great insights into the characteristics imprinted on our souls through the vibrations of our names.
If you could only secure the vibration of one trait for your child, what would you select?
Wisdom, curiosity, leadership, happiness/joy, kindness? Tell me, what you would choose if you could only choose one…
Recently, I’ve been reading about numerology and I’m slightly obsessed. I’ve always had a fascination with numbers. As a child, I actually enjoyed math because it made sense— there was always a set process to figure out the correct answer and I loved the feeling of being right (or to put it in nicer terms “obtaining knowledge” 😜).
As I got older, I found that I was drawn to certain numbers and certain categories of numbers (like evens vs odds, etc.). I even liked guys more if I liked their birthdate! 😐
My husband calls me superstitious. My friends call me quirky. Either way, learning more about numerology is now helping me to understand why I am as they perceive me.
Today, while stuck in the traffic of school drop offs, I had plenty of time to think— one of my favorite pastimes.
The words curiosity, enlightenment, thought, and kindness kept vibrating in my brain so I figured I would spend some time exploring why.
In so doing, I immediately got a visual of a life journey as if it were a road trip (side note: I actually love a good road trip! Oh, but I hate to drive, lol). On this trip, we need something with an engine to propel us forward — this is curiosity.
Stay with me…
Once the engine gets us going, we begin to encounter the world we live in on this journey. There are many paths and the knowledge we gain through these encounters with our world (if we pay attention) can lead to enlightenment — a peaceful, harmonious understanding of our universe and our place within it (my definition, not Webster’s 🧐).
Our thoughts (and time spent on reflection and meditation) can become the compass that we need to select heart-centered paths toward enlightenment. But we don’t always think before we do and that can cause detours, or off-road types of experiences.
Still, the greatest reward is in manifesting kindness at every stop, detour, or destination point in our life journey.
I tell my kids to think before they speak, not everything observed needs to be spoken. Still working on this myself, to be honest…
But if speak you must, then speak the truth and do it with kindness.
Kindness can be the hardest trait to manifest for some. It can be hard to conjure kindness after some of the egregious life events we encounter on our journey. But kindness heals the soul. I have seen this first hand. In the most painful circumstances, a measure of kindness can restore hope. It vibrates warmth and channels well-being.
If we can learn to express the experiences and lessons from our life journey through kindness, then we can create spaces of peace, harmony, and acceptance.
No, I haven’t been drinking yet, but I have had coffee— of course.
So tell me what you think of all my thinking in the comments below.
More sexy scenes coming soon, I promise!

domain: philosophy


text:
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Every hero has a beginning; either you came from a distant planet or starts off with a dark past. Either way it is your choice on what legacy you want to begin and for Bruce Wayne, it was to be the Dark Knight that Gotham needed. This is the supposed prequel to the other Arkham titles where you take on Gotham as a fresh start Batman against a lot of heavy hitters, but the question that everyone is asking, has Warner Bros Montreal succeeded in this Batman? We shall definitely get into that.
The main villain this time around is Blackmask and right now Blackgate has been infiltrated unleashing all of Gotham’s most deadly of villains. The only wrench standing in Sionis’s way is Batman himself, but he has a night selection of assassin’s to keep the Dark Knight occupied while his plans are coming together, or so we think. I am sorry I am going to have to stop right there, because I am still looking for the “Origins” portion of the game. I get the fact that they wanted to keep the title with the Franchise, but so far with Arkham Asylum and Arkham City, they made sense. This title is very misleading and I was trying to save my negative points for the end of this review, but I just can’t. Let’s just lay all of our cards on the table right now, this is not Batman year one. I say this because many people are under the impression that this is. If this was it would of made a better game title. The second thing…you are infiltrating blackgate, which has nothing to do with Arkham Asylum. The reason the other two titles were called that because you had to deal with Arkham Asylum and then it expanded into a whole city area. This one really has nothing to do with the Asylum and if you played the first one with the Easter egg of finding Arkham’s ghost, that would be the true origin.
Where are the changes from the other two titles? With this game being made by Warner Bros Montreal, I was expecting some differences especially being a fresh batman, but to my surprise; his gadgets are better than the previous titles. How is that possible? The enhanced and I do mean enhanced detective mode gives you a full spectrum of the crime scene and a play by play of what exactly happened. I mean you can do a recorded viewing of exactly what happened to a victim or in that area which was not in any of the other titles. If this is a “prequel”, I would not expect his gadgets to be that impressive. The second was the rocket batclaw…we didn’t get that until part two and we had to do those special glide missions just to unlock it, but they said to hell with it and gave it to us from jump…Wtf? Now some were complaining about the change of the buttons, but it was not that much of a drastic change. They only switched the trigger button layout and I was fine with that.
One of my readers Psychowulff who is on the Xbox 360 version made this valid point,
“Yes, its a little confusing about him being fresh in the game, but I already have gadgets that I would of had to unlock further in Arkham City.”
I found it strange that you encounter all these badass assassins Copperhead to Killer Croc, but when you face them the battles are very weak, especially Electrocutioner or whatever hell you call him. I thought it was funny, but this is no time to joke right now Montreal, this is your time to impress us as you took over for Rocksteady! I finally got the chance to encounter Deathstroke and I was much hyped to get in this fight, but it was over in less than five minutes…I am laughing at this other reviewer that shall remain nameless who stated it took him 30 minutes on easy to defeat him…really dude thirty minutes…on easy? Either way, I was expecting a deeper fight with him, but surely was disappointed with that outcome. I mean come on I can let Bane or Killer Croc slide, but this is Slade and as a first time in a game outside of DCUO encountering him. The fact that you had him as the main selling point for this new franchise, really hyping him up and it ends in under five minutes. Go in the corner Montreal, you are done here.
So, the game can be beaten straight through in 8 hours and then you have the extras, like game plus mode and I Am The Night mode which only grants you one life. Then of course you have the challenge maps which will be in game as before against other players to show who can be the better fighter. This has been a fan favorite throughout the series and always challenging to go against others scores. At this point I feel that WB Montreal was just fishing to cause more replay value, even though it is already there by adding the 3 vs. 3 vs. 2 online modes. The objectives are not confusing at all, but it is up to you to follow them and that was not the case. The idea was to capture and eliminate enemy adversaries. However, you can skip the main objective and just go all death-match by either winning the match killing the two heroes. I was on Bane side for the past three games and my buddy ended up being batman. He got me that one time, but after that I figured out the pattern and the robin was getting done to easily. The shooting mechanics are very bad in terms of when I was taken down by a slow gliding robin and was getting hit markers. It does give you a final break down of how you died and how much damage you inflicted on your opponent. Not for nothing, but at a certain point you get to run to the door to activate bane or joker and frankly Joker is stronger than Bane. It all depends on who uses them I guess, but Joker is a bada** character to control.
There is a lot to unlock in the mutli-player as you level up, but they still need to fix the lobby system and of course the mic support, which the indicator was there, but not working. If you want to get your friends in a room, you can either do a private match or join a quick game, however you must invite your friends fast or the lobby will fill up and you are stuck with randoms’. The customization and abilities are pretty decent, but still not strong enough for me to make a return to multi-player. The challenge maps are enough to satisfy me.
There is not much good I can say about this title and WB Montreal really didn’t make this title their own. It is quite disappointing and feels more like an expansion rather than a prequel story. They changed the voice actor from Kevin Conroy to Roger Craig Smith and I thought he did a good job, but did he sound younger? No, not really. That’s what I was told is the reason behind the voice acting change and batman does not look any younger prior to the other titles. The fact that they let you walk around the batcave was pretty neat and seeing that the batmobile was not built yet was very disappointing, since the car was his first mode of travel. Speaking of that the new fast travel feature is a nice touch, but you still have to travel around to take out the towers to even utilize it anyway. Side mission have to be hunted down this time, they are not gifted to you anymore and the A.I villains are not that much of a challenge, except for a selected few that can counter your counter. That is a problem because that should be for later games with an enhanced enemy of that nature!
Batman: Arkham Origins gets a 2.5 out of 5 and I am slightly upset at this, but the signs were all there from the beginning as time passed. If I were you, wait for the price to drop and get the Game of the Year edition with all the DLC, challenge maps and all that. Xbox 360 people do not be sadden that you could not get the nightfall costume or Adam West Costume, because they are just costumes and for my friend that was screaming out that he can run around as White Lantern Batman, unless I have the powers, it does not impress me at all. In multi-player you will unlock other costumes if you progress or bother to do so, but as for me I rather wait for Rocksteady to come back with something else or give us another DC game based on another character like Catwomen, Nightwing or Deathstroke.
That is all for me right now and please return for next week as we get into Battlefield 4 and Assassin’s Creed 4. Stay frosty gamers!
Developer: Warner Bros. Games Montréal
Publisher: Warner Bros. Interactive Entertainment
Genre: Action Adventure
Platforms: Nintendo WiiU, PC, Ps3, Xbox 360
Modes: Single-player, Multi-player
KKEnt’s Verdict: 2.5 out of 5

domain: game


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WARSHIP BATTLE:3D World War II (Mod) Apk Unlimited Gems and Money + MOD Latest version Free Download For Android
WARSHIP BATTLE:3D World War II Mod Apk is a ActionShooterVehicle combatCasual Android App. This application has age restrictions, the recommended age for using 15+ years. The latest official version has been installed on 10M+ devices. On a five-point scale, the application received a rating of 4.2 out of 1.0, a total of 679K people voted.
Game short description: WARSHIP BATTLE:3D World War II (Mod) Apk Unlimited Gems and Money mod APK is a modified version of WARSHIP BATTLE:3D World War II (Mod) Apk Unlimited Gems and Money. In this game, you can play with unlimited gems, Gold and Elixir. It is a free and multiplayer playing game on the internet. In this game you can make different buildings and construct your town bases, also you can make your own army attack other clans and defend your base in war. With the increase in level, you have new recourses and characters. These thrilling features make the game interesting.
App Information of WARSHIP BATTLE:3D World War II
|App Name :||WARSHIP BATTLE:3D World War II|
|Package Name :||com.joycity.warshipbattle|
|MOD Offered By :||presetjungle.com|
|Latest Updated :||2022-08-11T00:00:00.000Z|
|Category :||ActionShooterVehicle combatCasual|
|Playstore Link :|
App Description of WARSHIP BATTLE:3D World War II
#WARSHIP BATTLE:3D World War II (Mod) Apk Unlimited Gems and MoneyDownloadMOD
Thrilling news for the over 70 million fans of Gunship Battle!
Take the battle to the seas in WARSHIP BATTLE, a 3D warship action game, with missions inspired by the historic naval clashes of World War II.
From the USS Arizona to the HMS Bulldog, take control of authentic World War II era vessels and steer them through epic naval battles to glorious victory!
– High quality 3D graphics despite compact app size
– Fast paced naval battles with authentic warships from the World War II era
– Customize your warships with different weapons and parts to win the battle
– Episodes and hidden missions based on real WWII naval battles.
This game is free to play, but you can choose to pay real money for special in-game items.[Access Authorizations in JOYCITY Games]
1. Access to Contacts
(When logging into the game) It is essential to be able to identify the Google account registered in the device for Google Login. [Access to Contacts] includes information to read the Google account. You will be unable to login to the game if you deny the access request.
2. Access to Photos, Media, and Files
(When registering/editing profile) Access to [Photos, Media, and Files] saved in the device is required when you register/edit account profile image. Login and gameplay will not be affected even if you deny the access.
* Phrases used in [ ] may differ based on the device and OS version.
Download WARSHIP BATTLE:3D World War II Mod Apk
[New] Optimized the Alliance help feature
[New] You may now look for Alliance Members by using the search box.
OPTIMIZATION & BUG FIXES
[Optimization] Some heroes now have less repetitive battle animations.
Top War: Battle Game This app is available for free on presetjungle and Google Play 4.2 and up. All APK / XAPK files are 100% secure and can be downloaded quickly.
Now, Download this new version game WARSHIP BATTLE:3D World War II Mod Apk Unlimited Gems and Money + everything 2022 for free from the given links and enjoy.
Thank you for taking the time to look at my web page. Remember to return to presetjungle in the future. Every day, we keep you up to speed on the most fascinating Android games and applications.
- How to install:
1. Download Link WARSHIP BATTLE:3D World War II
2. Enter Settings / Security / Check Unknown Source (Source Not Known)
3. Then install until it’s finished
4. Play This Game
- WHAT’S NEW:
New features for screen cap button, in-app browser and QR join code
Added New version
Fixed Mod Link


US and India to sign nuclear deal
President Bush signed the accord into law earlier this week
The United States and India are due to sign a civilian nuclear co-operation accord to end 34 years of US sanctions.
US Secretary of State Condoleezza Rice and Indian foreign minister Pranab Mukherjee will sign the deal in Washington after years of negotiations.
India will gain access to US civilian nuclear technology and fuel in return for inspections of its civilian, but not military, nuclear facilities.
India says the accord is vital to meet its rising energy needs.
Critics say it creates a dangerous precedent.
They say it effectively allows India to expand its nuclear power industry without requiring it to sign the Non-Proliferation Treaty (NPT) as other nations must.
The US restricted nuclear co-operation with India after it tested a nuclear weapon in 1974.
US President George W Bush signed the accord into law earlier this week, after it had finally been approved by the US Congress.
The deal was first agreed three years ago and is regarded as a key foreign policy priority for both the Indian and US governments.
Indian Prime Minister Manmohan Singh has said the deal will help India to liberate itself from "the constraints of technology denial of 34 years".
Although India has said it retains the right to conduct nuclear tests, the US has said the deal would be cancelled in such an eventuality.
The Nuclear Suppliers Group (NSG) recently lifted a ban that had denied India access to the international nuclear market.
India and France have also signed a major co-operation pact which paves the way for the sale of French nuclear reactors to Delhi.
France is the world's second largest producer of nuclear energy after the United States.
Russia has also been lobbying the Indian government hard on behalf of its firms.


text:
"Touchdown confirmed," said engineer Allen Chen, the Flight Dynamics and Operations Lead for the Mars Science Laboratory Entry, Descent, and Landing team. "We're safe on Mars."
Learning from previous landings, engineers used a heat shield, a parachute, retro-rockets, and a sky crane to lower the vehicle to the surface. Because it would take 7 minutes for the rover to descend from the top of the atmosphere to the surface, but signals from the vehicle take about 14 minutes to reach Earth, the landing was dubbed "7 minutes of terror." See a NASA Jet Propulsion Laboratory video about the landing below.
The $2.5-million rover has been described as a chemistry set on wheels and includes cameras and instruments to look for signs that Mars has the chemical resources to support microbial life. The rover is outfitted with an X-band transmitter for communication and a radiation detector to gather information for human missions in the future.
Curiosity's landing site was Gale Crater, with plans to study the crater's exposed bedrock and its peak, Mount Sharp. Since the landing, Curiosity has found evidence of a lakebed with fresh water that existed billions of years ago, and investigated more than 600 Martian rock and soil targets with its ChemCam laser.
Curiosity is now traveling toward "long-term science destinations" on the lower slopes of Mount Sharp, where it has encountered hazardous sharp rock terrain that the rover team has had to navigate carefully.
NASA plans to launch the InSight Mars lander in 2016 (with plans to look deep inside Mars), has announced the Mars 2020 rover, and is participating in the European Space Agency's ExoMars missions.
According to EDN

domain: astronomy


text:
The Veterans of Foreign War Post 1303 is on the move and looking to shed some pounds
Everything from the popcorn machine to bingo balls will be for sale during a Saturday auction to clean out the VFW building at 3715 9th St., Rock Island.
The VFW has sold the building for $600,000 to the city of Rock Island, and if all goes according to plan, the property will be one of several in the area torn down to make way for a new Walmart Supercenter.
Post commander P.J. Hymes said the building became the VFW's base in December 1993 after the post moved out of downtown Rock Island.Now, the post again is looking for a new home.
"We are looking to downsize a little bit," Mr. Hymes said, adding that after debts are cleared, theVFW will have about $400,000 to shop for a new building.
The post has 357 members, not counting members of the ladies auxiliary, and has had a presence in Rock Island for 78 years, Mr. Hymes said.
"We're still continuing doing what we've always done," he said. "We're still an active, live VFW."
Meetings are being held at the Moose Lodge at 4410 9th St, Rock Island, until the VFW finds a new building. Mr. Hymes said they're looking for a building that's "the perfect fit."
Saturday's auction starts at 10 a.m. People can view items beginning at 8:30 a.m., with bid registration starting at 9 a.m. Items up for auction include kitchen equipment, furniture, office items and miscellaneous equipment.
For more information, call auctioneer Brian Lees at 309-235-4071 or email email@example.com
Today is Wednesday, April 23, the 113th day of 2014. There are 252 days left in the year.
1864 — 150 years ago: Some persons are negotiating for 80 feet of ground on Illinois Street with a view of erecting four stores thereon. It would serve a better purpose if the money was invested in neat tenement houses. 1889 — 125 years ago: The Central station, car house and stables of the Moline-Rock Island Horse Railway line of the Holmes syndicate, together with 15 cars and 42 head of horses, were destroyed by fire. The loss was at $15,000. 1914 — 100 years ago: Vera Cruz, Mexico, after a day and night of resistance to American forces, gradually ceased opposition. The American forces took complete control of the city. 1939 — 75 years ago: Dr. R. Bruce Collins was reelected for a second term as president of the Lower Rock Island County Tuberculosis Association. 1964 — 50 years ago: Work is scheduled to begin this summer on construction of a new men's residence complex and an addition to the dining facilities at Westerlin Hall at Augustana College. 1989 — 25 years ago: Special Olympics competitors were triple winners at Rock Island High School Saturday. The participants vanquished the rain that fell during the competition, and some won their events; but most important, they triumphed over their own disabilities.

domain: history


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I love these sandwiches. They’re a vegetarian cross between a New Orleans–style muffuletta (hey olive salad!) and a Philadelphia-style pork and broccoli rabe sandwich. They’re also inspired by a passage I once read about how legendary food writer M. F. K. Fisher made a guest sit on a wrapped sandwich while they chatted so it would be perfectly pressed in time for lunch. Ha! When these sandwiches are pressed, the olive and caper mixture soaks into the bread and the cheese and garlicky broccoli rabe become really good friends. The broccoli rabe can also be served as a side dish with the olive mixture spooned on top (or you can mix the lot with cooked pasta and call it dinner). If you can’t find or don’t like broccoli rabe, substitute regular broccoli or any dark, leafy green such as kale.
Average user rating
Percentage of reviewers who will make this recipe again

domain: food


Scientific study is underway to discover how the animal lived and died, and how its bones became a living reef for encrusting animals. The specimen was scanned at the University of Southampton using its high-energy, micro-focus CT scanner. The results were used to reconstruct a three dimensional digital model of the entire skull, revealing fine details of the creature's internal structure that would otherwise remain a mystery.
The University of Bristol are using this CT scan data to understand just how powerful the bite may have been. Experts from the University of Portsmouth are studying the fossilisation process, while mud associated with the bones has been sent to the University of Plymouth, to see if any fossil plankton were preserved. Sediment removed from the bones is being studied by experts in the Natural History Museum in search of bones and teeth of animals that may have hunted around the dead skeleton.
More about pliosaurs
Despite their giant size, the oldest pliosaurs had many teeth, indicating they had a diet of fish. But over time they developed fewer, stronger teeth suggesting they evolved to hunt large prey such as big fish and other marine reptiles. Just like many of today’s predators, pliosaurs probably disabled their prey and allowed them to weaken through blood loss before going in for the kill.
The Weymouth Bay pliosaur, one of the most complete and best preserved skulls ever found, has provided new insights into our understanding of how these enormous animals evolved. Giant pliosaurs were first found in the UK in the early 1800s, but most fossils were fragmentary, so their species diversity has been uncertain.
One of the most significant finds is that the genus Pliosaurus appears to have developed a highly effective body plan that remained little changed for millions of years. During that time, just a handful of species evolved and this is unlike most top predators in the fossil record which reach dominance but were then typically swiftly replaced by different forms.
The research has been undertaken by a team of vertebrate palaeontologists from Oxford, Bristol and Cambridge universities and with Leicester, Nottingham and the Sedgwick (Cambridge) museums together with independent researchers.


Acoustic absorption and the unsteady flow associated with circular apertures in a gas turbine environment
2013-08-20T09:16:36Z (GMT) by
This work is concerned with the fluid dynamic processes and the associated loss of acoustic energy produced by circular apertures within noise absorbing perforated walls. Although applicable to a wide range of engineering applications particular emphasis in this work is placed on the use of such features within a gas turbine combustion system. The primary aim for noise absorbers in gas turbine combustion systems is the elimination of thermo-acoustic instabilities, which are characterised by rapidly rising pressure amplitudes which are potentially damaging to the combustion system components. By increasing the amount of acoustic energy being absorbed the occurrence of thermo-acoustic instabilities can be avoided. The fundamental acoustic characteristics relating to linear acoustic absorption are presented. It is shown that changes in orifice geometry, in terms of gas turbine combustion system representative length-to-diameter ratios, result in changes in the measured Rayleigh Conductivity. Furthermore in the linear regime the maximum possible acoustic energy absorption for a given cooling mass flow budget of a conventional combustor wall will be identified. An investigation into current Rayleigh Conductivity and aperture impedance (1D) modelling techniques are assessed and the ranges of validity for these modelling techniques will be identified. Moreover possible improvements to the modelling techniques are discussed. Within a gas turbine system absorption can also occur in the non-linear operating regime. Hence the influence of the orifice geometry upon the optimum non-linear acoustic absorption is also investigated. Furthermore the performance of non-linear acoustic absorption modelling techniques is evaluated against the conducted measurements. As the amplitudes within the combustion system increase the acoustic absorption will transition from the linear to the non-linear regime. This is important for the design of absorbers or cooling geometries for gas turbine combustion systems as the propensity for hot gas ingestion increases. Hence the relevant parameters and phenomena are investigated during the transition process from linear to non-linear acoustic absorption. The unsteady velocity field during linear and non-linear acoustic absorption is captured using particle image velocimetry. A novel analysis technique is developed which enables the identification of the unsteady flow field associated with the acoustic absorption. In this way an investigation into the relevant mechanisms within the unsteady flow fields to describe the acoustic absorption behaviour of the investigated orifice plates is conducted. This methodology will also help in the development and optimisation of future damping systems and provide validation for more sophisticated 3D numerical modelling methods. Finally a set of design tools developed during this work will be discussed which enable a comprehensive preliminary design of non-resonant and resonant acoustic absorbers with multiple perforated liners within a gas turbine combustion system. The tool set is applied to assess the impact of the gas turbine combustion system space envelope, complex swirling flow fields and the propensity to hot gas ingestion in the preliminary design stages.


text: Pokémon Red, Blue, Yellow and Green are the first Pokémon games. It takes place in the Kanto region where you play as a trainer you name. Pokémon Green was only released in Japan. In Pokémon Red, Blue and Green you choose between Squirtle, Bulbasaur and Charmander as a starter but in Pokémon Yellow you immediately get Pikachu as a starter. It's available on the original GameBoy and was rereleased on the 3DS E-Shop as a Virtual Console game in 2016. It was also remade for the GameBoy Advanced under the name FireRed and LeafGreen.


text:
Enemark, Daniel McCubbins, Mathew D. and Weller, Nicholas 2014. Knowledge and networks: An experimental test of how network knowledge affects coordination. Social Networks, Vol. 36, p. 122.
Huth, Paul K. Croco, Sarah E. and Appel, Benjamin J. 2013. Bringing Law to the Table: Legal Claims, Focal Points, and the Settlement of Territorial Disputes Since 1945. American Journal of Political Science, Vol. 57, Issue. 1, p. 90.
Baccini, Leonardo and Kim, Soo Yeon 2012. Preventing protectionism: International institutions and trade policy. The Review of International Organizations, Vol. 7, Issue. 4, p. 369.
Brochmann, Marit 2012. Signing River Treaties—Does It Improve River Cooperation?. International Interactions, Vol. 38, Issue. 2, p. 141.
Chikozho, Claudious 2012. Rethinking Development Challenges for Public Policy.
Gilligan, Michael J. and Johns, Leslie 2012. Formal Models of International Institutions. Annual Review of Political Science, Vol. 15, Issue. 1, p. 221.
Huth, Paul Croco, Sarah and Appel, Benjamin 2012. Law and the Use of Force in World Politics: The Varied Effects of Law on the Exercise of Military Power in Territorial Disputes. International Studies Quarterly, Vol. 56, Issue. 1, p. 17.
Urpelainen, Johannes 2012. How uncertainty about outside options impedes international cooperation. International Theory, Vol. 4, Issue. 01, p. 133.
Brochmann, Marit and Hensel, Paul R. 2011. The Effectiveness of Negotiations over International River Claims1. International Studies Quarterly, Vol. 55, Issue. 3, p. 859.
Schneider, Christina J. 2011. Weak States and Institutionalized Bargaining Power in International Organizations1. International Studies Quarterly, Vol. 55, Issue. 2, p. 331.
Simonelli, Nicole M. 2011. Bargaining over International Multilateral Agreements: The Duration of Negotiations. International Interactions, Vol. 37, Issue. 2, p. 147.
Carmona, Salvador Donoso, Rafael and Walker, Stephen P. 2010. Accounting and international relations: Britain, Spain and the Asiento treaty. Accounting, Organizations and Society, Vol. 35, Issue. 2, p. 252.
Risse, Thomas and Kleine, Mareike 2010. Deliberation in negotiations. Journal of European Public Policy, Vol. 17, Issue. 5, p. 708.
Gray, Julia 2009. International Organization as a Seal of Approval: European Union Accession and Investor Risk. American Journal of Political Science, Vol. 53, Issue. 4, p. 931.
Büthe, Tim and Milner, Helen V. 2008. The Politics of Foreign Direct Investment into Developing Countries: Increasing FDI through International Trade Agreements?. American Journal of Political Science, Vol. 52, Issue. 4, p. 741.
Dongwook Won, 2008. Scientific Uncertainty and a Dilemma of Environmental Cooperation in Northeast Asia: A Game-theoretic Approach. Korean Political Science Review, Vol. 42, Issue. 4, p. 369.
Johns, Leslie 2007. A Servant of Two Masters: Communication and the Selection of International Bureaucrats. International Organization, Vol. 61, Issue. 02,
Kleine, Mareike 2007. Leadership in the European Convention. Journal of European Public Policy, Vol. 14, Issue. 8, p. 1227.
McLaughlin Mitchell, Sara and Hensel, Paul R. 2007. International Institutions and Compliance with Agreements. American Journal of Political Science, Vol. 51, Issue. 4, p. 721.
The problems of distribution and information impede international cooperation. They arise when actors select how they will cooperate. An exploration of the interaction between these problems using a limited information model of cooperation leads to six conclusions. First, leadership solutions to coordination problems always exist, but leadership here is very different from hegemonic provision of public goods. Second, actors can cooperate in the face of anarchy even without a shadow of the future. Third, diffuse reciprocal strategies arise naturally in coordination problems. Fourth, norms and institutions are intertwined within successful cooperation. Fifth, the form of cooperation on an issue varies with the relative importance of distribution and information. Finally and most important, distributional and informational problems interfere with each other. Arrangements to cooperate can successfully address one, but not both, of these problems.
This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.
Email your librarian or administrator to recommend adding this journal to your organisation's collection.

domain: library


text:
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domain: photo


text:
A Study on the Vision-Based Flexible Vibratory Feeding System
This paper describes a vision-based flexible vibratory feeding system (VBFVFS) for agile manufacturing, which mainly consists of a decupled vibratory feeder, a machine vision system, displacement sensors, power amplifiers and a computer system. Its major feeding parameters such as the vibration angle, frequency, acceleration amplitude, and phase difference all can be easily adjusted online by software means. Consequently, the system not only can feed a wide range of parts without any retooling of the feeder, but also can feed various parts made of different material in a way close to the optimal state. The VBFVFS also has intelligence. It can find out the natural frequencies of the decoupled vibratory feeder by means of automatic frequency response analysis and hence determine the best frequency for the driving signals. It can also find out any parts jamming and eliminate it by making the parts move in reverse directions. Prototypes of the decoupled vibratory feeder have been successfully developed. Experimental investigation is carried out based on the prototypes and the results agree well with the simulation results. Moreover low-cost vision technique is also discussed for the commercialization of the vision-based flexible vibratory feeding system.
Fei Hu and Beibei Wang
L. Han et al., "A Study on the Vision-Based Flexible Vibratory Feeding System", Advanced Materials Research, Vol. 279, pp. 434-439, 2011

domain: design


In the intricate web of energy distribution systems, a silent guardian ensures that the flow of natural gas remains safe, reliable, and optimized: the natural gas line regulator. Often overlooked, these unassuming devices play a critical role in maintaining pressure, safeguarding against hazards, and enhancing efficiency in the distribution of natural gas. This article uncovers the inner workings and significance of natural gas line regulators in our modern energy landscape.
Understanding Natural Gas Line Regulators
Natural gas line regulators are mechanical devices designed to control the pressure of natural gas as it transitions from high-pressure transmission lines to lower-pressure distribution systems. These regulators are integral to ensuring that the gas reaches consumers at a consistent pressure suitable for various applications, ranging from residential heating to industrial manufacturing.
Functionality and Importance
- Pressure Control: The primary purpose of a natural gas line regulator is to reduce the high-pressure gas from transmission lines to a safe and manageable level for consumption. This pressure reduction prevents potential dangers associated with high-pressure gas entering homes, businesses, and industrial facilities.
- Safety Assurance: Natural gas is highly flammable and poses a risk when not handled properly. Regulators act as a safety barrier by maintaining a controlled pressure, minimizing the likelihood of leaks, fires, and explosions.
- Efficient Energy Distribution: Different appliances and machinery require specific gas pressures to function efficiently. Regulators ensure that the right pressure is delivered, optimizing the performance of gas-powered equipment and reducing energy wastage.
The operation of natural gas line regulators relies on a combination of components, including diaphragms, springs, and valves:
- Pressure Sensing: The regulator monitors the incoming gas pressure and compares it to a pre-set desired pressure.
- Adjustment Mechanism: If the incoming pressure is higher than the desired pressure, a diaphragm or piston responds by adjusting the valve’s position. This restricts the flow of gas and reduces pressure.
- Pressure Balance: As the pressure approaches the desired level, the diaphragm or piston maintains equilibrium with the spring force, positioning the valve to stabilize the gas pressure at the outlet.
- Steady Flow: The gas, now regulated to the appropriate pressure, flows through the outlet of the regulator, ready for safe distribution and usage.
Types of Natural Gas Line Regulators
Two main types of natural gas line regulators are commonly employed:
- Direct-Operated Regulators: These simple regulators utilize the gas system’s own pressure to control their functioning. They are ideal for lower-pressure applications and require minimal external intervention.
- Pilot-Operated Regulators: More complex and capable of handling higher pressures, pilot-operated regulators incorporate a separate control circuit (pilot) to manage the main regulator. They find utility in industrial contexts where precision and robustness are essential.
Challenges and Safety Measures
While natural gas line regulators are essential for safety and efficiency, they face challenges related to external factors such as demand fluctuations and changes in gas composition. Maintenance and regular inspections are vital to ensure proper regulator performance.
To bolster safety, regulators are equipped with safety mechanisms like overpressure protection and pressure relief valves. These features act as fail-safes, preventing catastrophic pressure build-ups and ensuring the system’s integrity.
In the intricate dance of energy distribution, the natural gas line regulator stands as a stalwart guardian. Its unassuming design and critical role in pressure control ensure that the energy we rely on reaches us safely and efficiently. From our stoves at home to the factories that power our industries, the work of these regulators often goes unnoticed, but their impact is immeasurable. As we navigate the complexities of modern energy systems, let’s remember the vital contribution of natural gas line regulators in upholding safety, efficiency, and the seamless flow of energy.