slug stringlengths 3 55 | topic stringlengths 22 84 | url stringlengths 23 75 | canonical_name stringlengths 3 53 | category stringclasses 31
values | alternate_names listlengths 0 16 | datePublished timestamp[s]date 2026-06-26 00:00:00 2026-07-30 00:00:00 | dateModified timestamp[s]date 2026-06-26 00:00:00 2026-07-30 00:00:00 | lastReviewed timestamp[s]date 2026-06-26 00:00:00 2026-07-30 00:00:00 | conclusion stringlengths 1.17k 1.77k | citation listlengths 0 21 | markdown stringlengths 33k 55.9k |
|---|---|---|---|---|---|---|---|---|---|---|---|
17_dmag | 17-DMAG for Health & Longevity | https://evipedia.ai/17_dmag | 17-DMAG | medication | [
"Alvespimycin",
"Alvespimycin Hydrochloride",
"17-Dimethylaminoethylamino-17-demethoxygeldanamycin",
"KOS-1022",
"NSC 707545",
"DMAG"
] | 2026-07-18T00:00:00 | 2026-07-18T00:00:00 | 2026-07-18T00:00:00 | 17-DMAG is an experimental compound that blocks a cellular helper protein many damaged and worn-out cells rely on to survive. Built decades ago as a cancer drug, it later became interesting for longevity because it can selectively destroy the aged, "zombie" cells that accumulate over time and inflame nearby tissue. In ... | [
{
"name": "Identification of HSP90 inhibitors as a novel class of senolytics",
"url": "https://pubmed.ncbi.nlm.nih.gov/28871086/",
"pmid": "28871086"
},
{
"name": "Targeted cancer therapy through 17-DMAG as an Hsp90 inhibitor: Overview and current state of the art",
"url": "https://pubmed.nc... | ---
canonical_name: 17-DMAG
alternate_names: Alvespimycin, Alvespimycin Hydrochloride, 17-Dimethylaminoethylamino-17-demethoxygeldanamycin, KOS-1022, NSC 707545, DMAG
canonical_topic: 17-DMAG for Health & Longevity
short_topic_lc: 17_dmag
creation_date: 2026-0718-1651
creator_ai_fullname: Opus 4.8
ep_keywords: HSP90 In... |
3haa | 3HAA for Health & Longevity | https://evipedia.ai/3haa | 3HAA | compound | [
"3-Hydroxyanthranilic Acid",
"3-HAA",
"3-HANA",
"3-Hydroxyanthranilate",
"2-Amino-3-hydroxybenzoic Acid"
] | 2026-07-30T00:00:00 | 2026-07-30T00:00:00 | 2026-07-30T00:00:00 | 3HAA is a natural molecule the body makes while breaking down a common dietary amino acid. It has moved from being seen as a throwaway, possibly harmful byproduct to a candidate worth studying for healthy aging, largely because raising it helped small laboratory animals live longer and stay healthier, apparently by str... | [
{
"name": "On the benefits of the tryptophan metabolite 3-hydroxyanthranilic acid in Caenorhabditis elegans and mouse aging",
"url": "https://pubmed.ncbi.nlm.nih.gov/38097593/",
"pmid": "38097593"
},
{
"name": "Exercise training restores longevity-associated tryptophan metabolite 3-hydroxyanthra... | ---
canonical_name: 3HAA
alternate_names: 3-Hydroxyanthranilic Acid, 3-HAA, 3-HANA, 3-Hydroxyanthranilate, 2-Amino-3-hydroxybenzoic Acid
canonical_topic: 3HAA for Health & Longevity
short_topic_lc: 3haa
creation_date: 2026-0730-0009
creator_ai_fullname: Opus 4.8
---
# 3HAA for Health & Longevity
<section id="top" mark... |
40_hz_ultrasound | 40 Hz Ultrasound for Health & Longevity | https://evipedia.ai/40_hz_ultrasound | 40 Hz Ultrasound | brain | [
"40 Hz Transcranial Ultrasound Stimulation",
"40 Hz Pulsed Ultrasound",
"Gamma-Frequency Ultrasound",
"40 Hz Transcranial Focused Ultrasound",
"40 Hz TUS",
"Gamma-Entrainment Ultrasound"
] | 2026-07-04T00:00:00 | 2026-07-04T00:00:00 | 2026-07-04T00:00:00 | 40 Hz ultrasound is an early-stage, non-invasive idea: gentle sound-wave energy aimed through the skull and pulsed forty times a second to nudge the brain's fast "gamma" rhythm, with the hope of clearing sticky plaques, calming inflammation, and supporting memory as the brain ages. Its distinctive promise is reaching d... | [
{
"name": "Gamma oscillations and application of 40-Hz audiovisual stimulation to improve brain function",
"url": "https://pubmed.ncbi.nlm.nih.gov/36374520/",
"pmid": "36374520"
},
{
"name": "Effects of transcranial ultrasound stimulation pulsed at 40 Hz on Aβ plaques and brain rhythms in 5×FAD ... | ---
canonical_name: 40 Hz Ultrasound
alternate_names: 40 Hz Transcranial Ultrasound Stimulation, 40 Hz Pulsed Ultrasound, Gamma-Frequency Ultrasound, 40 Hz Transcranial Focused Ultrasound, 40 Hz TUS, Gamma-Entrainment Ultrasound
canonical_topic: 40 Hz Ultrasound for Health & Longevity
short_topic_lc: 40_hz_ultrasound
c... |
5_amino_1mq | 5-Amino-1MQ for Health & Longevity | https://evipedia.ai/5_amino_1mq | 5-Amino-1MQ | compound | [
"5-Amino-1-methylquinolinium",
"5-AMQ",
"5A1MQ",
"5-Amino-1-methylquinoline"
] | 2026-07-15T00:00:00 | 2026-07-15T00:00:00 | 2026-07-15T00:00:00 | 5-Amino-1MQ is a purpose-built small molecule that blocks an enzyme, NNMT, which becomes overactive in fat tissue and aging muscle. By doing so, it helps cells hold onto more of the fuel-and-repair molecule NAD⁺ and the body's main methyl donor, nudging cells to burn fat rather than store it. In obese mice it reduced f... | [
{
"name": "Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice",
"url": "https://pubmed.ncbi.nlm.nih.gov/29155147/",
"pmid": "29155147"
},
{
"name": "Nicotinamide N-methyltransferase (NNMT): a novel therapeu... | ---
canonical_name: 5-Amino-1MQ
alternate_names: 5-Amino-1-methylquinolinium, 5-AMQ, 5A1MQ, 5-Amino-1-methylquinoline
canonical_topic: 5-Amino-1MQ for Health & Longevity
short_topic_lc: 5_amino_1mq
creation_date: 2026-0715-0250
creator_ai_fullname: Opus 4.8
---
# 5-Amino-1MQ for Health & Longevity
<section id="top" ma... |
5_htp | 5-HTP for Health & Longevity | https://evipedia.ai/5_htp | 5-HTP | compound | [
"5-Hydroxytryptophan",
"Oxitriptan",
"L-5-Hydroxytryptophan",
"5-Hydroxy-L-tryptophan"
] | 2026-07-22T00:00:00 | 2026-07-22T00:00:00 | 2026-07-22T00:00:00 | "5-HTP is a natural building block the body uses to make serotonin, the messenger tied to mood, slee(...TRUNCATED) | [{"name":"5-Hydroxytryptophan (5-HTP): Natural Occurrence, Analysis, Biosynthesis, Biotechnology, Ph(...TRUNCATED) | "---\ncanonical_name: 5-HTP\nalternate_names: 5-Hydroxytryptophan, Oxitriptan, L-5-Hydroxytryptophan(...TRUNCATED) |
5_meo_dmt | 5-MeO-DMT for Health & Longevity | https://evipedia.ai/5_meo_dmt | 5-MeO-DMT | psychedelics | [
"5-Methoxy-N,N-dimethyltryptamine",
"Mebufotenin",
"O-Methylbufotenin",
"5-Methoxy-DMT"
] | 2026-07-28T00:00:00 | 2026-07-28T00:00:00 | 2026-07-28T00:00:00 | "5-MeO-DMT is an exceptionally potent, very short-acting psychedelic — found in a desert toad, in (...TRUNCATED) | [{"name":"A narrative synthesis of research with 5-MeO-DMT","url":"https://pubmed.ncbi.nlm.nih.gov/3(...TRUNCATED) | "---\ncanonical_name: 5-MeO-DMT\nalternate_names: 5-Methoxy-N,N-dimethyltryptamine, Mebufotenin, O-M(...TRUNCATED) |
78_dihydroxyflavone | 7,8-Dihydroxyflavone for Health & Longevity | https://evipedia.ai/78_dihydroxyflavone | 7,8-Dihydroxyflavone | compound | [
"Tropoflavin",
"7,8-DHF"
] | 2026-07-24T00:00:00 | 2026-07-24T00:00:00 | 2026-07-24T00:00:00 | "7,8-Dihydroxyflavone is a plant-derived molecule that switches on the same brain receptor as a natu(...TRUNCATED) | [{"name":"7,8-dihydroxyflavone, a small molecular TrkB agonist, is useful for treating various BDNF-(...TRUNCATED) | "---\ncanonical_name: 7,8-Dihydroxyflavone\nalternate_names: Tropoflavin, 7,8-DHF\ncanonical_topic: (...TRUNCATED) |
9_methyl_carboline | 9-Methyl-β-Carboline for Health & Longevity | https://evipedia.ai/9_methyl_carboline | 9-Methyl-β-Carboline | compound | [
"9-Me-BC",
"9-MBC",
"9-Methylnorharman",
"9-Methyl-9H-pyrido[3,4-b]indole"
] | 2026-07-16T00:00:00 | 2026-07-16T00:00:00 | 2026-07-16T00:00:00 | "9-Methyl-β-Carboline is an experimental compound from a chemical family better known for harming b(...TRUNCATED) | [{"name":"Stimulation, protection and regeneration of dopaminergic neurons by 9-methyl-β-carboline:(...TRUNCATED) | "---\ncanonical_name: 9-Methyl-β-Carboline\nalternate_names: \"9-Me-BC, 9-MBC, 9-Methylnorharman, 9(...TRUNCATED) |
acarbose | Acarbose for Health & Longevity | https://evipedia.ai/acarbose | Acarbose | medication | [
"Precose",
"Glucobay",
"Prandase",
"Acarbosum",
"BAY g 5421"
] | 2026-07-03T00:00:00 | 2026-07-03T00:00:00 | 2026-07-03T00:00:00 | "Acarbose is a long-approved diabetes medication that works entirely in the gut, slowing the digesti(...TRUNCATED) | [{"name":"A systematic review, meta-analysis, dose-response, and meta-regression of the effects of a(...TRUNCATED) | "---\ncanonical_name: Acarbose\nalternate_names: Precose, Glucobay, Prandase, Acarbosum, BAY g 5421\(...TRUNCATED) |
acetate | Acetate for Health & Longevity | https://evipedia.ai/acetate | Acetate | compound | [
"Acetic Acid",
"Ethanoate",
"Acetate Ion"
] | 2026-07-24T00:00:00 | 2026-07-24T00:00:00 | 2026-07-24T00:00:00 | "Acetate is a simple, naturally occurring compound — the acid in vinegar and a major product of fi(...TRUNCATED) | [{"name":"Vinegar (acetic acid) intake on glucose metabolism: A narrative review","url":"https://pub(...TRUNCATED) | "---\ncanonical_name: Acetate\nalternate_names: Acetic Acid, Ethanoate, Acetate Ion\ncanonical_topic(...TRUNCATED) |
End of preview. Expand in Data Studio
Evipedia Evidence Reviews
The full public catalogue of evipedia.ai — a continuously-updated encyclopedia of evidence reviews on health & longevity interventions — as one record per review. Each record carries the review's metadata plus its complete Markdown body.
- Homepage / source: https://evipedia.ai
- Live file: https://evipedia.ai/evipedia-corpus.jsonl (this dataset mirrors it)
- Publisher: Forever Healthy
- License: CC BY 4.0
What's inside
One JSON object per line (JSON Lines). One line per live review.
| Field | Type | Description |
|---|---|---|
slug |
string | Short id / last path segment of the permalink (e.g. rapamycin). |
topic |
string | Review title (e.g. "Rapamycin for Health & Longevity"). |
url |
string | Canonical review URL on evipedia.ai. |
canonical_name |
string | Intervention name (e.g. "Rapamycin"). |
category |
string | Evipedia category (e.g. medication, compound, diet). |
alternate_names |
string[] | Synonyms / brand names. |
datePublished / dateModified / lastReviewed |
string (ISO date) | Review dates. |
conclusion |
string | Plain-text conclusion of the review. |
citation |
object[] | Primary-source references — {name, url, pmid?} (PMID for PubMed sources). |
markdown |
string | The complete evidence review as Markdown (the review body). |
How it's produced
Generated at site build time from the live evidence reviews and served at
/evipedia-corpus.jsonl; this dataset mirrors that file. It contains only the
public catalogue (the same reviews listed on the site, in /reviews.json, and in
the search index).
Uses
Retrieval-augmented generation, semantic search over health-intervention evidence, summarization, and fine-tuning / evaluation on evidence-grounded medical text. Every record links back to its canonical review and its primary sources.
Updates
The source reviews are refreshed on average every 4–6 weeks; this dataset is re-synced from the live file (see the repo's refresh job).
Attribution
Reuse freely under CC BY 4.0, including for AI training and generation, provided
you credit evipedia.ai and, where practical, link back to the review's
permalink (the url field).
Limitations
Evipedia's reviews are AI-generated and audited; see the limitations & disclaimer. This is educational evidence synthesis, not medical advice.
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