logical_unit_id string | example_id string | messages list | task_type string | split string | graph_unit_id string | difficulty int32 | hop_count int32 | source_node_ids list | source_edge_ids list | source_triples list | answer_entity_ids list | relation_ids list | negative_strategy string | generation_mode string | prompt_version string | generator_model string | validation_results string | kg_name string | kg_version string | kg_sha256 string | sources list | licenses list | metadata string |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
90ab91f060cf2219b3d5eb343f3c623adbce022331ecc0f6e05b1e6db8a2d903 | 1b5406679a782b694e549da30eaeb97f2340092f5c447f0b0f21d7a7af125509 | [
{
"content": "What compound does Ifenprodil resemble chemically?",
"role": "user"
},
{
"content": "Ifenprodil chemically resembles Cloperastine.",
"role": "assistant"
}
] | atomic_qa | train | 3344d8efc6034d8389e46121599a0cd24329f09ed0174d338537ac0fa2f712b7 | 1 | 1 | [
"Compound::DB08954",
"Compound::DB09002"
] | [
"67c84239a04a4d3f827230cef3c0da8a615e910ab947067a8c4d0f6a677438d5"
] | [
{
"edge_id": "67c84239a04a4d3f827230cef3c0da8a615e910ab947067a8c4d0f6a677438d5",
"source_id": "Compound::DB08954",
"source_name": "Ifenprodil",
"relation_id": "Compound-resembles-Compound",
"target_id": "Compound::DB09002",
"target_name": "Cloperastine"
}
] | [
"Compound::DB09002"
] | [
"Compound-resembles-Compound"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 10} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Dice similarity of ECFPs",
"DrugBank"
] | [
"CC BY-NC 4.0",
"CC0 1.0"
] | {"known_id": "Compound::DB08954", "query_direction": "forward", "structural_split_key": "21558b6a6aba92d1ac077bfd60b28dd3c84be73542831b8918f6ea718a859c81"} |
af3d1f1729bc7a80b5ee110f95927243ba216265e67336a667529b86292dd509 | 7286f62c5ce9026b4ff4c02ffa10271f9cfa97e8c05a788696a7eedd6c33ce45 | [
{
"content": "What gene is linked to Parkinson's disease?",
"role": "user"
},
{
"content": "The gene linked to Parkinson's disease is SOD1.",
"role": "assistant"
}
] | atomic_qa | train | 8fb877b80b54404d8fc913f1c2d5b186108c05e1f7fcd39b805a7e821c195144 | 1 | 1 | [
"Disease::DOID:14330",
"Gene::6647"
] | [
"7512cb4bd47b08343125716db7722080e7914326531c88eeda66cdfd97dbf43b"
] | [
{
"edge_id": "7512cb4bd47b08343125716db7722080e7914326531c88eeda66cdfd97dbf43b",
"source_id": "Disease::DOID:14330",
"source_name": "Parkinson's disease",
"relation_id": "Disease-associates-Gene",
"target_id": "Gene::6647",
"target_name": "SOD1"
}
] | [
"Gene::6647"
] | [
"Disease-associates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 15} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"Entrez Gene",
"UNSPECIFIED"
] | [
"CC BY 3.0",
"CC0 1.0",
"ODbL 1.0"
] | {"known_id": "Disease::DOID:14330", "query_direction": "forward", "structural_split_key": "e253c0f1956435180b04f615f34bfe18176a2c90941c49de3d8bd32fa511272e"} |
d70ec406f32f1d70c3759f011903cfa36b374221b702568b10d8039a88ec891f | f56d2c2b9a7f7452097643f2b181e07fc0f755797f0a47207b2c53dbc13ded42 | [
{
"content": "Which gene is expressed in the adrenal gland?",
"role": "user"
},
{
"content": "The C2CD3 gene is expressed in the adrenal gland.",
"role": "assistant"
}
] | atomic_qa | train | 1b9e0a686a2b62d04e2ae47459ea832d7b94c790bc05a4ecc6a0f59526b675bb | 1 | 1 | [
"Anatomy::UBERON:0002369",
"Gene::26005"
] | [
"1106ad6d49e423055109f36b243ca45230f59c1e7b90a817888e670337af071a"
] | [
{
"edge_id": "1106ad6d49e423055109f36b243ca45230f59c1e7b90a817888e670337af071a",
"source_id": "Anatomy::UBERON:0002369",
"source_name": "adrenal gland",
"relation_id": "Anatomy-expresses-Gene",
"target_id": "Gene::26005",
"target_name": "C2CD3"
}
] | [
"Gene::26005"
] | [
"Anatomy-expresses-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 17} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Entrez Gene",
"UNSPECIFIED",
"Uberon"
] | [
"CC BY 3.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Anatomy::UBERON:0002369", "query_direction": "forward", "structural_split_key": "c7e7d64c0b4de473b72a6324209acef70628f2299cbd44b6b110c1ebeecad8dc"} |
b6eee693ca9e6180f3da8b8d4cdf7c5a5e7cd99b1d7a66cd4746f3a40003fcaf | 22d98f2d2f97bdd76a23bb0ec22a4ed1807f22f4f6856d6086fddf4b341214d4 | [
{
"content": "Which gene shows an evolutionary covariation with DOK7?",
"role": "user"
},
{
"content": "HTRA3",
"role": "assistant"
}
] | atomic_qa | train | a3aaf5c42c6b027e3b4bdc8b98a15f556207d214bfd12a4c72b32a7de8b17687 | 1 | 1 | [
"Gene::94031",
"Gene::285489"
] | [
"fd42cccb90dfdbe7175bbb2b1528ecb37549c5380e52fa2ba0f94e6f46a22f8e"
] | [
{
"edge_id": "fd42cccb90dfdbe7175bbb2b1528ecb37549c5380e52fa2ba0f94e6f46a22f8e",
"source_id": "Gene::94031",
"source_name": "HTRA3",
"relation_id": "Gene-covaries-Gene",
"target_id": "Gene::285489",
"target_name": "DOK7"
}
] | [
"Gene::94031"
] | [
"Gene-covaries-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 9} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"ERC",
"Entrez Gene"
] | [
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Gene::285489", "query_direction": "inverse", "structural_split_key": "c057c22fa9f570a598cbd3be81cc261916c41255de5a5df8c4a20343487fc5a9"} |
65207f19593ddd12361b534270134f3a39ab322475084469f25df1bfe6439fef | 3084752e7a899f302da67bfa004f4971c89df2372e338eeade023575652282fd | [
{
"content": "Which part of the body expresses IRF2BP2?",
"role": "user"
},
{
"content": "IRF2BP2 is expressed in the digestive system.",
"role": "assistant"
}
] | atomic_qa | train | 36b67fef87295a84fa9a4d0f9d8393d18163a682d718f256c1012232d7090976 | 1 | 1 | [
"Anatomy::UBERON:0001007",
"Gene::359948"
] | [
"2f91d12e092d57a14ffc9cf589b0049e526a495f372d31a94293096bd4c8b0b6"
] | [
{
"edge_id": "2f91d12e092d57a14ffc9cf589b0049e526a495f372d31a94293096bd4c8b0b6",
"source_id": "Anatomy::UBERON:0001007",
"source_name": "digestive system",
"relation_id": "Anatomy-expresses-Gene",
"target_id": "Gene::359948",
"target_name": "IRF2BP2"
}
] | [
"Anatomy::UBERON:0001007"
] | [
"Anatomy-expresses-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 14} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Entrez Gene",
"UNSPECIFIED",
"Uberon"
] | [
"CC BY 3.0",
"CC BY 4.0",
"CC0 1.0"
] | {"known_id": "Gene::359948", "query_direction": "inverse", "structural_split_key": "a87f3e4d67c76efac7fb13a44ecee0726d170f85650c3b8f9cc7e0d5804ddf1f"} |
cc44aaac5467b35fdcd9e23ba092f02b94234b84c4b0a98d94152593a7a58623 | e0d076e6ae00307e3abf28a589745f0fd83ff799e6b97379cd56cae6093db590 | [
{
"content": "In which part of the body is the ARNT gene under-expressed in post-juvenile adult human samples?",
"role": "user"
},
{
"content": "The ARNT gene is under-expressed in the spinal cord in post-juvenile adult human samples.",
"role": "assistant"
}
] | atomic_qa | train | 83039cc87af4b934a917adfd9eb351a7147e660660100c28bf4d8843cfe50056 | 1 | 1 | [
"Anatomy::UBERON:0002240",
"Gene::405"
] | [
"999983b8c9a007cb6ec9ce4f793839516d73634ac113114ee5203755d9e51d00"
] | [
{
"edge_id": "999983b8c9a007cb6ec9ce4f793839516d73634ac113114ee5203755d9e51d00",
"source_id": "Anatomy::UBERON:0002240",
"source_name": "spinal cord",
"relation_id": "Anatomy-downregulates-Gene",
"target_id": "Gene::405",
"target_name": "ARNT"
}
] | [
"Anatomy::UBERON:0002240"
] | [
"Anatomy-downregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 30} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Bgee",
"Entrez Gene",
"Uberon"
] | [
"CC BY 3.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Gene::405", "query_direction": "inverse", "structural_split_key": "39c1ce6509f74f63dc49f5670ae2d843a20750be0d89b8c8eb73675ce76df559"} |
7a3591a434d96ae806ace9c440e906a1802c13e65cc6c97dfb0522ae042ff564 | 412df603df64d584f5f0f4ce2aa3b73a0c33be88af05ac347c84ee358639fcd2 | [
{
"content": "What condition is PSEN2 linked to?",
"role": "user"
},
{
"content": "PSEN2 is linked to Alzheimer's disease.",
"role": "assistant"
}
] | atomic_qa | train | 05dc4bc8bc8b7e6db0b54943bfc5b9d701b5b1bb4536e8262c036f03b34bd479 | 1 | 1 | [
"Disease::DOID:10652",
"Gene::5664"
] | [
"e2c0cd8bfb2d6480aecd5137fe9444b44cb73f5d52651021cd5cbde4be70892a"
] | [
{
"edge_id": "e2c0cd8bfb2d6480aecd5137fe9444b44cb73f5d52651021cd5cbde4be70892a",
"source_id": "Disease::DOID:10652",
"source_name": "Alzheimer's disease",
"relation_id": "Disease-associates-Gene",
"target_id": "Gene::5664",
"target_name": "PSEN2"
}
] | [
"Disease::DOID:10652"
] | [
"Disease-associates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 12} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"Entrez Gene",
"UNSPECIFIED"
] | [
"CC BY 3.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Gene::5664", "query_direction": "inverse", "structural_split_key": "4d487be655dbbe828307a6c577da25fecf9e5b06c5747bb2da216ad49679835b"} |
f66a99a55ffea4bf6bc2050d3875a29a4bb85fb680a1e9dc2f60ba33bf9af906 | 2c0cb1720ac98f31eeb782a120ffb1f6a37fedebebd1eb08136a2e39973ad856 | [
{
"content": "What side effect is Atropine known to cause?",
"role": "user"
},
{
"content": "Atropine is known to cause clumsiness.",
"role": "assistant"
}
] | atomic_qa | train | dce9bae10e6e4dec7aebdbd613441620412c0d9e74cb9733faaee623e32ddb9f | 1 | 1 | [
"Compound::DB00572",
"Side Effect::C0233844"
] | [
"527398e703685fe3f9bace8eeb0436209d9b56648403a3f1e10866bb5c5f2a94"
] | [
{
"edge_id": "527398e703685fe3f9bace8eeb0436209d9b56648403a3f1e10866bb5c5f2a94",
"source_id": "Compound::DB00572",
"source_name": "Atropine",
"relation_id": "Compound-causes-Side Effect",
"target_id": "Side Effect::C0233844",
"target_name": "Clumsiness"
}
] | [
"Side Effect::C0233844"
] | [
"Compound-causes-Side Effect"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 14} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"SIDER 4.1",
"UMLS via SIDER 4.1"
] | [
"CC BY-NC 4.0",
"CC BY-NC-SA 4.0"
] | {"known_id": "Compound::DB00572", "query_direction": "forward", "structural_split_key": "8cc46865024ae345f4bd9226603bdfc06fba576039892d915248ba8752e24bee"} |
52dc3c495c49e83dfa1841e10e235036949a1892032ec46b33587bd829fb103f | aaeef3b782ac121c9ce169950ae4ef7a22f5c84f80bd934f45ebe429dffdf586 | [
{
"content": "Which gene shows evolutionary covariance with ODF1?",
"role": "user"
},
{
"content": "BRSK1.",
"role": "assistant"
}
] | atomic_qa | train | 3d78081f38b08897e8f2196874925514c6ac0ef4a132aed5046d1112843f9cb5 | 1 | 1 | [
"Gene::4956",
"Gene::84446"
] | [
"a6b7a3b18595e04a7766db6d20ea1a3995c61a9e98a9b89dd7151bbd55ab2319"
] | [
{
"edge_id": "a6b7a3b18595e04a7766db6d20ea1a3995c61a9e98a9b89dd7151bbd55ab2319",
"source_id": "Gene::4956",
"source_name": "ODF1",
"relation_id": "Gene-covaries-Gene",
"target_id": "Gene::84446",
"target_name": "BRSK1"
}
] | [
"Gene::84446"
] | [
"Gene-covaries-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 8} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"ERC",
"Entrez Gene"
] | [
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Gene::4956", "query_direction": "forward", "structural_split_key": "0634374d6d6a9c8fb630f6637f3bf4dd4be428bafd4c5798be5987ca54ac379e"} |
a98523bbc89455c878642b02e226a8fb52cf3bbf715d1af9f0a45adbe020121d | 6df07aa64b7c9eb81fe05d95701b8f21c130018744453b07204779d2403597fa | [
{
"content": "In which part of the body is the RGS8 gene over-expressed in post-juvenile adult human samples?",
"role": "user"
},
{
"content": "The RGS8 gene is over-expressed in the cerebellum in post-juvenile adult human samples.",
"role": "assistant"
}
] | atomic_qa | train | d515f97fc9c00d01e9bd662b997140ec23731f2a63890b75f7b883f87b4e1486 | 1 | 1 | [
"Anatomy::UBERON:0002037",
"Gene::85397"
] | [
"4411db5024d29f0d0acc1686f2e38ce64ee906c50a78f6aa23f0a1400b670393"
] | [
{
"edge_id": "4411db5024d29f0d0acc1686f2e38ce64ee906c50a78f6aa23f0a1400b670393",
"source_id": "Anatomy::UBERON:0002037",
"source_name": "cerebellum",
"relation_id": "Anatomy-upregulates-Gene",
"target_id": "Gene::85397",
"target_name": "RGS8"
}
] | [
"Anatomy::UBERON:0002037"
] | [
"Anatomy-upregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 29} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Bgee",
"Entrez Gene",
"Uberon"
] | [
"CC BY 3.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Gene::85397", "query_direction": "inverse", "structural_split_key": "b907434b105297b7b618e5273273675c8209f934bfbc62e28abb9b878c63075a"} |
c42c42aaf14df131a2baa34f63c9cec0288580869adc128c0c2c16aef3d95d75 | 2288b1bd51388e3c333d7698b5e91d5f6b4656121909445ca3c7648f0d1e086d | [
{
"content": "Which gene shows higher expression in the testis of post-juvenile adult human samples?",
"role": "user"
},
{
"content": "CCDC15 shows higher expression in the testis of post-juvenile adult human samples.",
"role": "assistant"
}
] | atomic_qa | train | 46227f8b08a5a1caba73386ff0dcbea537afdf95c7d46abf3270e2bde4217146 | 1 | 1 | [
"Anatomy::UBERON:0000473",
"Gene::80071"
] | [
"cd8136f9e33246dca6a5af643670953725a1714c4ef404b9d7a96b1b89cf0085"
] | [
{
"edge_id": "cd8136f9e33246dca6a5af643670953725a1714c4ef404b9d7a96b1b89cf0085",
"source_id": "Anatomy::UBERON:0000473",
"source_name": "testis",
"relation_id": "Anatomy-upregulates-Gene",
"target_id": "Gene::80071",
"target_name": "CCDC15"
}
] | [
"Gene::80071"
] | [
"Anatomy-upregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 25} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Bgee",
"Entrez Gene",
"Uberon"
] | [
"CC BY 3.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Anatomy::UBERON:0000473", "query_direction": "forward", "structural_split_key": "270029840a3e6a39a1c9b53217c3ec82b826df71aab4659726dc2e0888a7cb79"} |
a00d36d3e04ce82d4b96a552e15deabe92c8015f154ccfe3f45e7c8790866fea | 04412338ddd202ff87b0d770111cb24c4082106313d965c1912496b28c0eb396 | [
{
"content": "Which gene is upregulated by exposure to Ouabain?",
"role": "user"
},
{
"content": "Exposure to Ouabain upregulates the YY1AP1 gene.",
"role": "assistant"
}
] | atomic_qa | train | 30881f5573f8f179e93841ffd40d1d038c05afc3fab792f70a43cc2131f1013f | 1 | 1 | [
"Compound::DB01092",
"Gene::55249"
] | [
"3b41a354022a25d3ca96f6ad342693234d384a3608867936d1f3341b99b2e159"
] | [
{
"edge_id": "3b41a354022a25d3ca96f6ad342693234d384a3608867936d1f3341b99b2e159",
"source_id": "Compound::DB01092",
"source_name": "Ouabain",
"relation_id": "Compound-upregulates-Gene",
"target_id": "Gene::55249",
"target_name": "YY1AP1"
}
] | [
"Gene::55249"
] | [
"Compound-upregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 15} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"Entrez Gene",
"LINCS L1000"
] | [
"CC BY-NC 4.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Compound::DB01092", "query_direction": "forward", "structural_split_key": "490bc2997459bb87c0fd1b2bd35acb87ce66838a012e3fe91212bdbde8f9dc09"} |
90dc8458482627f338395fa9e4b311660730f297fe0cd4c87a23a568cf844576 | 80bc5666af0e49a70ea4d3bf59dbb76a8311b958424b48e945b264f5a2626dad | [
{
"content": "What compound is Trifluoperazine structurally similar to?",
"role": "user"
},
{
"content": "Trifluoperazine is structurally similar to Zuclopenthixol.",
"role": "assistant"
}
] | atomic_qa | train | e894070cf936f5fa9cd86686702734d6e5b8e6e36bcded758186027378b74e71 | 1 | 1 | [
"Compound::DB01624",
"Compound::DB00831"
] | [
"9608a7266e2b04ad2619af40860b9ec156a142210011efd32d0f3433909c770f"
] | [
{
"edge_id": "9608a7266e2b04ad2619af40860b9ec156a142210011efd32d0f3433909c770f",
"source_id": "Compound::DB01624",
"source_name": "Zuclopenthixol",
"relation_id": "Compound-resembles-Compound",
"target_id": "Compound::DB00831",
"target_name": "Trifluoperazine"
}
] | [
"Compound::DB01624"
] | [
"Compound-resembles-Compound"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 13} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Dice similarity of ECFPs",
"DrugBank"
] | [
"CC BY-NC 4.0",
"CC0 1.0"
] | {"known_id": "Compound::DB00831", "query_direction": "inverse", "structural_split_key": "10bc49ac3ec109de2045642ee2a38b6c173f55bb343d14e0b77045d01b2f25b4"} |
ae0905e44b9c64a5bc163bb00d62e8e4eb22c8f137550e0d81df2800525329a3 | d44f8b5cb900fe51c905794181f0b21f374e121c29c8588a3202b6b3d9254a7a | [
{
"content": "In post-juvenile adult human samples, DHCR7 is under-expressed in which part of the body?",
"role": "user"
},
{
"content": "DHCR7 is under-expressed in the blood in post-juvenile adult human samples.",
"role": "assistant"
}
] | atomic_qa | train | cbe2b0bcc6e8995961162c65da06be725f844df43dee9b65d507dcee62ee393e | 1 | 1 | [
"Anatomy::UBERON:0000178",
"Gene::1717"
] | [
"587916caef74460a6d217a02c0e2f030c8aa9e56e9e3685cf3156685c49968c3"
] | [
{
"edge_id": "587916caef74460a6d217a02c0e2f030c8aa9e56e9e3685cf3156685c49968c3",
"source_id": "Anatomy::UBERON:0000178",
"source_name": "blood",
"relation_id": "Anatomy-downregulates-Gene",
"target_id": "Gene::1717",
"target_name": "DHCR7"
}
] | [
"Anatomy::UBERON:0000178"
] | [
"Anatomy-downregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 25} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Bgee",
"Entrez Gene",
"Uberon"
] | [
"CC BY 3.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Gene::1717", "query_direction": "inverse", "structural_split_key": "396e717bba3d01448e2b89f94b700725923c02d0b14264fd9e30b1d7aa87a5ca"} |
15a315b5e2e9ee328f44beb4e689b2bfa73a001f202d2c31fa46b9fa545d0f64 | e114422d2840ff088f8c0cb7344eb8e081b0f85df34f36ce89aebdb86737ea68 | [
{
"content": "Which gene is responsible for the molecular function of protein phosphatase binding?",
"role": "user"
},
{
"content": "The gene responsible for this function is SOD1.",
"role": "assistant"
}
] | atomic_qa | train | 3497e0689e6a7586a67215452cc828544b60ddc74a9f352902b02c8737af8421 | 1 | 1 | [
"Gene::6647",
"Molecular Function::GO:0019903"
] | [
"5bf9012f1f44076304520d7476671644d15d670ab76d38823a004dded07ce153"
] | [
{
"edge_id": "5bf9012f1f44076304520d7476671644d15d670ab76d38823a004dded07ce153",
"source_id": "Gene::6647",
"source_name": "SOD1",
"relation_id": "Gene-participates-Molecular Function",
"target_id": "Molecular Function::GO:0019903",
"target_name": "protein phosphatase binding"
}
] | [
"Gene::6647"
] | [
"Gene-participates-Molecular Function"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 20} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Entrez Gene",
"Gene Ontology",
"NCBI gene2go"
] | [
"CC BY 4.0",
"CC0 1.0"
] | {"known_id": "Molecular Function::GO:0019903", "query_direction": "inverse", "structural_split_key": "d487192fc9460de54131fcb7f5930611bead01670adcd12415cc486df267ee4b"} |
e2d447811a391733a0df2c9fb1bf6a93941fd6a1f72501f0f54d8355f5f61496 | 48ab40af7dc13108e547870e8d9dbfee2fff44efdcb9cfea2bd75120bcd54f70 | [
{
"content": "Which gene does acquired immunodeficiency syndrome upregulate?",
"role": "user"
},
{
"content": "acquired immunodeficiency syndrome upregulates HLA-E.",
"role": "assistant"
}
] | atomic_qa | train | aea30168314fbcc06923b372061871ee0ef24675aad63aafa450df2d77bf7fa5 | 1 | 1 | [
"Disease::DOID:635",
"Gene::3133"
] | [
"f787ec6fa08e0f9f510bfaa27edaabf9f49d15f4bdf123a1944b4d8140fb440d"
] | [
{
"edge_id": "f787ec6fa08e0f9f510bfaa27edaabf9f49d15f4bdf123a1944b4d8140fb440d",
"source_id": "Disease::DOID:635",
"source_name": "acquired immunodeficiency syndrome",
"relation_id": "Disease-upregulates-Gene",
"target_id": "Gene::3133",
"target_name": "HLA-E"
}
] | [
"Gene::3133"
] | [
"Disease-upregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 12} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"Entrez Gene",
"STARGEO"
] | [
"CC BY 3.0",
"CC0 1.0"
] | {"known_id": "Disease::DOID:635", "query_direction": "forward", "structural_split_key": "aea168960c2c5b19c7d6f232fb81c9fdc7213f1351e93bcf6cdc11c7db600f0f"} |
70a601c36abab8cf5b4b335adffb25de9555d7ea916b2be3d101287800070762 | 514705d242c01903e98c9ff07fc5bd4a4a16bc5a1c91cbf566490409846507a8 | [
{
"content": "What molecular function is associated with the product of ACVR1?",
"role": "user"
},
{
"content": "The product of ACVR1 is involved in peptide binding.",
"role": "assistant"
}
] | atomic_qa | train | ede297dfa9eeb44c673e4a4472102e41f536886aef97ac6ea6b7ef65868ad8e4 | 1 | 1 | [
"Gene::90",
"Molecular Function::GO:0042277"
] | [
"0e4dbc7b225ea0caaf1f82aeff404056d620c35f66635e867238311c3b82bf17"
] | [
{
"edge_id": "0e4dbc7b225ea0caaf1f82aeff404056d620c35f66635e867238311c3b82bf17",
"source_id": "Gene::90",
"source_name": "ACVR1",
"relation_id": "Gene-participates-Molecular Function",
"target_id": "Molecular Function::GO:0042277",
"target_name": "peptide binding"
}
] | [
"Molecular Function::GO:0042277"
] | [
"Gene-participates-Molecular Function"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 19} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Entrez Gene",
"Gene Ontology",
"NCBI gene2go"
] | [
"CC BY 4.0",
"CC0 1.0"
] | {"known_id": "Gene::90", "query_direction": "forward", "structural_split_key": "f8585966a6ab608beb5f126bdf5fd0845edcdee869e0b9f1ffa07a11e62d3af2"} |
2a91e78b991adba07de4d96f958836de926b24afc3bc1d6a85685544aafad6f5 | f86977487b679de8daff6dfece0af9951b4280dd4cc50b3ec637d5ed37c53433 | [
{
"content": "Which compound causes SLC1A4 to be upregulated in samples?",
"role": "user"
},
{
"content": "SLC1A4 is upregulated in samples exposed to Vemurafenib.",
"role": "assistant"
}
] | atomic_qa | train | b841163f0bf6078def50768de4aa19c869dbfd6e3290493a2a32a7045a0c33c7 | 1 | 1 | [
"Compound::DB08881",
"Gene::6509"
] | [
"e709a08ed661dc2e9036dcede29d79048b84e2b91f093d841364a272f59b5059"
] | [
{
"edge_id": "e709a08ed661dc2e9036dcede29d79048b84e2b91f093d841364a272f59b5059",
"source_id": "Compound::DB08881",
"source_name": "Vemurafenib",
"relation_id": "Compound-upregulates-Gene",
"target_id": "Gene::6509",
"target_name": "SLC1A4"
}
] | [
"Compound::DB08881"
] | [
"Compound-upregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 17} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"Entrez Gene",
"LINCS L1000"
] | [
"CC BY-NC 4.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Gene::6509", "query_direction": "inverse", "structural_split_key": "577914f8edad659b4ccc791e48a59e0c7f300b86ce75d485762db30a4ea8e962"} |
bc32a2a5c0818fea91dcb3bdabd1198bdea3c60f5358b9349cc2c78a435fd11a | 871e27f005d8d3d14c9df86c975aeb38937995ad76b4f4421b79d2e7a0338e7c | [
{
"content": "Which compound causes TAP2 to be upregulated?",
"role": "user"
},
{
"content": "Doxorubicin causes TAP2 to be upregulated.",
"role": "assistant"
}
] | atomic_qa | train | dd1a81b9968e41ee547d3be5e20fab2797aef40fea1ce2099c4a258267112a33 | 1 | 1 | [
"Compound::DB00997",
"Gene::6891"
] | [
"817c2d52182bda69a2f116a81b73b23b2ff6f7ab41e311be07c13dc2fcb53ecd"
] | [
{
"edge_id": "817c2d52182bda69a2f116a81b73b23b2ff6f7ab41e311be07c13dc2fcb53ecd",
"source_id": "Compound::DB00997",
"source_name": "Doxorubicin",
"relation_id": "Compound-upregulates-Gene",
"target_id": "Gene::6891",
"target_name": "TAP2"
}
] | [
"Compound::DB00997"
] | [
"Compound-upregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 13} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"Entrez Gene",
"LINCS L1000"
] | [
"CC BY-NC 4.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Gene::6891", "query_direction": "inverse", "structural_split_key": "106db8bc7eb3b0a7e9b75ae279bb2039c7ae01ed8358526bec022bdece6004e4"} |
7c7ee241c27b2d460dad7ec1dd3b3906695fed13710fdefa90f555dd77e93eaa | 133b52b91b0d798fc3881e72252ed2699267bbe7d69bd425bb7ca9ca52649139 | [
{
"content": "Which gene has its expression increased by exposure to Aminolevulinic acid?",
"role": "user"
},
{
"content": "Exposure to Aminolevulinic acid upregulates the NUCB2 gene.",
"role": "assistant"
}
] | atomic_qa | train | b78bb8d634fb011107f39607fdef13bb7b4a270dbec6f68538a19be05eeb7808 | 1 | 1 | [
"Compound::DB00855",
"Gene::4925"
] | [
"b6dde62344d9b7528dfab49813cdb7fd0e164324ac66c0234c2ba9843c6dc84c"
] | [
{
"edge_id": "b6dde62344d9b7528dfab49813cdb7fd0e164324ac66c0234c2ba9843c6dc84c",
"source_id": "Compound::DB00855",
"source_name": "Aminolevulinic acid",
"relation_id": "Compound-upregulates-Gene",
"target_id": "Gene::4925",
"target_name": "NUCB2"
}
] | [
"Gene::4925"
] | [
"Compound-upregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 19} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"Entrez Gene",
"LINCS L1000"
] | [
"CC BY-NC 4.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Compound::DB00855", "query_direction": "forward", "structural_split_key": "8c61dc15b5883637386875a7c62422d1c0f4554e8f8882736dafe22ba21e6751"} |
17d8cc7d426acb0a01c76c8e5fde358f57852d43812127b14231df626593d8f3 | b1f62a5e65f6b7b4ab1fb224f6405e3af2c9b5334a1084702326042efde64353 | [
{
"content": "What disease is associated with the geniculate ganglion?",
"role": "user"
},
{
"content": "The geniculate ganglion is associated with peripheral nervous system neoplasm.",
"role": "assistant"
}
] | atomic_qa | train | 9bab8cd0d3af5c361c5522b8e1155eb170ef634394c4214f69eb4bbca25526e2 | 1 | 1 | [
"Disease::DOID:1192",
"Anatomy::UBERON:0001700"
] | [
"1eaaeba16151ded44d1b0def80b48cf9e447f46b8a4ac2e7f52eb06d4393e13d"
] | [
{
"edge_id": "1eaaeba16151ded44d1b0def80b48cf9e447f46b8a4ac2e7f52eb06d4393e13d",
"source_id": "Disease::DOID:1192",
"source_name": "peripheral nervous system neoplasm",
"relation_id": "Disease-localizes-Anatomy",
"target_id": "Anatomy::UBERON:0001700",
"target_name": "geniculate ganglion"
... | [
"Disease::DOID:1192"
] | [
"Disease-localizes-Anatomy"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 18} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"MEDLINE cooccurrence",
"Uberon"
] | [
"CC BY 3.0",
"CC0 1.0"
] | {"known_id": "Anatomy::UBERON:0001700", "query_direction": "inverse", "structural_split_key": "3423757f14087d2fed353f67ece2437d1eb2dd27636d4faf6ea70a5541a5c2d9"} |
e8148c67e5e00b09bc20180525249ae45af5247108ad21b77ea18cc0c1290e5a | 823d5f81ac6081664f100d49f0214f352b32595a06af06d86f40644c351b738a | [
{
"content": "Which gene shows higher expression in the urethra of post-juvenile adult human samples?",
"role": "user"
},
{
"content": "ADGRG1 shows higher expression in the urethra of post-juvenile adult human samples.",
"role": "assistant"
}
] | atomic_qa | train | 67fc677b2bf12d4966ee8b05d3706f4258148903c0d3f9516fe4adcdc929ce67 | 1 | 1 | [
"Anatomy::UBERON:0000057",
"Gene::9289"
] | [
"cc03ee712595ece83b2faa691f357a17df88bcd664adbb640e018b65d63a3c65"
] | [
{
"edge_id": "cc03ee712595ece83b2faa691f357a17df88bcd664adbb640e018b65d63a3c65",
"source_id": "Anatomy::UBERON:0000057",
"source_name": "urethra",
"relation_id": "Anatomy-upregulates-Gene",
"target_id": "Gene::9289",
"target_name": "ADGRG1"
}
] | [
"Gene::9289"
] | [
"Anatomy-upregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 25} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Bgee",
"Entrez Gene",
"Uberon"
] | [
"CC BY 3.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Anatomy::UBERON:0000057", "query_direction": "forward", "structural_split_key": "6050559b3611edea07cbe0bac470d39e1fea46d9843692a78ec5a8b094dbf797"} |
d29af9c656ed1db54b794c770c39f32842b97d37bb8c9c653ef4a44d2f47af35 | 4dded1fc2e0b6fef0409bf07345389fcd71bda86260fad5135fd015a0e820b62 | [
{
"content": "Which compound binds to the protein produced by SHMT1?",
"role": "user"
},
{
"content": "Mimosine binds to the protein product of SHMT1.",
"role": "assistant"
}
] | atomic_qa | train | 78f5e9fe6ac9bf4a9426ee47dbc6ef640c0d0dc22cb9d4e5f4e9cb3d8595b855 | 1 | 1 | [
"Compound::DB01055",
"Gene::6470"
] | [
"014b1054cc78d7d8cbbfa4a8bd92b1892188fc8c72fa35a8d40b668b805a98cb"
] | [
{
"edge_id": "014b1054cc78d7d8cbbfa4a8bd92b1892188fc8c72fa35a8d40b668b805a98cb",
"source_id": "Compound::DB01055",
"source_name": "Mimosine",
"relation_id": "Compound-binds-Gene",
"target_id": "Gene::6470",
"target_name": "SHMT1"
}
] | [
"Compound::DB01055"
] | [
"Compound-binds-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 17} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"Entrez Gene",
"UNSPECIFIED"
] | [
"CC BY-NC 4.0",
"CC0 1.0"
] | {"known_id": "Gene::6470", "query_direction": "inverse", "structural_split_key": "de0fd8c80b6db8937c5f4c1f37b4b70dcd6e65feee16a0ef076cedf68a595de0"} |
ef7af7e8d52fa89c84dfac05965a4fa1ce8a613eda3167b2182b6e7859283c8c | 0c24805b979a617cf6792f07cd0908707cf4273a00b10bc446301552404a52ef | [
{
"content": "What compound is chemically similar to Salicylamide?",
"role": "user"
},
{
"content": "Salicylamide is chemically similar to Acetylsalicylic acid.",
"role": "assistant"
}
] | atomic_qa | train | 8c990bc79947a09b0179177cb855310a525a25f3beda2e1853ab6039cf47cb24 | 1 | 1 | [
"Compound::DB00945",
"Compound::DB08797"
] | [
"55735fda5496a5270c68b0a05d137dd48e86c83f17e575b82038aada64b9c07b"
] | [
{
"edge_id": "55735fda5496a5270c68b0a05d137dd48e86c83f17e575b82038aada64b9c07b",
"source_id": "Compound::DB00945",
"source_name": "Acetylsalicylic acid",
"relation_id": "Compound-resembles-Compound",
"target_id": "Compound::DB08797",
"target_name": "Salicylamide"
}
] | [
"Compound::DB00945"
] | [
"Compound-resembles-Compound"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 14} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Dice similarity of ECFPs",
"DrugBank"
] | [
"CC BY-NC 4.0",
"CC0 1.0"
] | {"known_id": "Compound::DB08797", "query_direction": "inverse", "structural_split_key": "6d5d50d9132bfce6aec784da4f41f8570d6b6e858db0a8be493ecaeabef02392"} |
6e939ec0f132de0d339cc2c32a5be98434f2a37fdc54c84dbd394543087d59e6 | 1625a8fc515913f27626f5130ee605b80df56face966b39e284a65d4f3294b93 | [
{
"content": "What compound is chemically similar to Scopolamine?",
"role": "user"
},
{
"content": "Methylscopolamine bromide.",
"role": "assistant"
}
] | atomic_qa | train | 5b3717e092c64950324c7d125a2c039407d458ce1c5ff265671b192452fadbb4 | 1 | 1 | [
"Compound::DB00747",
"Compound::DB00462"
] | [
"935e4d19800a3183d2b3fd5569647070e2a2a47b9ce5d7fac2505fd4a06254e9"
] | [
{
"edge_id": "935e4d19800a3183d2b3fd5569647070e2a2a47b9ce5d7fac2505fd4a06254e9",
"source_id": "Compound::DB00747",
"source_name": "Scopolamine",
"relation_id": "Compound-resembles-Compound",
"target_id": "Compound::DB00462",
"target_name": "Methylscopolamine bromide"
}
] | [
"Compound::DB00462"
] | [
"Compound-resembles-Compound"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 9} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Dice similarity of ECFPs",
"DrugBank"
] | [
"CC BY-NC 4.0",
"CC0 1.0"
] | {"known_id": "Compound::DB00747", "query_direction": "forward", "structural_split_key": "77b8c01b53bbaf8f6674bf0d9c8f75a99380c73995e7dc8f909192d7504df709"} |
26449327f4762085f04e566ce6b36460f7d69a43ffadec418e17b592d6e32780 | 081884a5272dd6ccbd85df15628a290ce1b3435acd96ff942893e3beb9a28060 | [
{
"content": "What cellular component does the AKT2 protein contribute to?",
"role": "user"
},
{
"content": "The AKT2 protein contributes to the leading edge membrane.",
"role": "assistant"
}
] | atomic_qa | train | 1f0c4bdc85e2a99f983276690124a4261db5d96af7d2be82bc27e5d31d7f5147 | 1 | 1 | [
"Gene::208",
"Cellular Component::GO:0031256"
] | [
"aa6f1073bb4a0f503c4336f62c4492ca5f73a0d711fe7b88d3f98d5902406430"
] | [
{
"edge_id": "aa6f1073bb4a0f503c4336f62c4492ca5f73a0d711fe7b88d3f98d5902406430",
"source_id": "Gene::208",
"source_name": "AKT2",
"relation_id": "Gene-participates-Cellular Component",
"target_id": "Cellular Component::GO:0031256",
"target_name": "leading edge membrane"
}
] | [
"Cellular Component::GO:0031256"
] | [
"Gene-participates-Cellular Component"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 18} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Entrez Gene",
"Gene Ontology",
"NCBI gene2go"
] | [
"CC BY 4.0",
"CC0 1.0"
] | {"known_id": "Gene::208", "query_direction": "forward", "structural_split_key": "3325e2407dacb42288728a18a2040ab360702fef8f18100dc5e8ac8041e3f557"} |
6ae01d2f906bf938f53aaf86b9476909ad7812882a77e78c7afc4bce2a35f9c5 | d08f4a999ef186cb454e09da18785eb5fbe050311c22019597cc935aedc11caa | [
{
"content": "Which gene's expression is reduced by exposure to Ropivacaine?",
"role": "user"
},
{
"content": "Exposure to Ropivacaine downregulates the HOXA5 gene.",
"role": "assistant"
}
] | atomic_qa | train | 395b20e4adcf761396539c173a9bfcef56278f33d178b81e408f8931f0c959d5 | 1 | 1 | [
"Compound::DB00296",
"Gene::3202"
] | [
"515f6d5479160432b2e0735d096735b7d1ba4ea4c31bf65ee0b2a8ddae90d689"
] | [
{
"edge_id": "515f6d5479160432b2e0735d096735b7d1ba4ea4c31bf65ee0b2a8ddae90d689",
"source_id": "Compound::DB00296",
"source_name": "Ropivacaine",
"relation_id": "Compound-downregulates-Gene",
"target_id": "Gene::3202",
"target_name": "HOXA5"
}
] | [
"Gene::3202"
] | [
"Compound-downregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 16} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"Entrez Gene",
"LINCS L1000"
] | [
"CC BY-NC 4.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Compound::DB00296", "query_direction": "forward", "structural_split_key": "aa7f07c4a7b59e22c6d0d70e7b3663f0ba721cf0e80bef8746edb51f25d2204d"} |
60fa5e122b772c6b8ae0a8fb1b89c47ee501af07bcbf22769cb13790c64d731c | fa3d5d5d329c6ca465d3dbbfb1757607ac73026fdc28932263df662c1a7e7dd8 | [
{
"content": "What gene is linked to schizophrenia?",
"role": "user"
},
{
"content": "C11orf87 is the gene associated with schizophrenia.",
"role": "assistant"
}
] | atomic_qa | train | 2197a96b5529b00a314b9c8d192e1a4c4a698a8d2ba9868feadc2ce117145d89 | 1 | 1 | [
"Disease::DOID:5419",
"Gene::399947"
] | [
"e2d5b0fe49324c8209b6b43b12c77b34083593830367919f31d8e701e7f98745"
] | [
{
"edge_id": "e2d5b0fe49324c8209b6b43b12c77b34083593830367919f31d8e701e7f98745",
"source_id": "Disease::DOID:5419",
"source_name": "schizophrenia",
"relation_id": "Disease-associates-Gene",
"target_id": "Gene::399947",
"target_name": "C11orf87"
}
] | [
"Gene::399947"
] | [
"Disease-associates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 13} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"Entrez Gene",
"UNSPECIFIED"
] | [
"CC BY 3.0",
"CC BY 4.0",
"CC0 1.0"
] | {"known_id": "Disease::DOID:5419", "query_direction": "forward", "structural_split_key": "079f5d7ebba9891217f2d5af0a64dcfd0c8c703a673752bdd6014523cbeff5ba"} |
f7277773b1f10ee5eb1b7d8ae95b422f03a2ef4b4f608c66a35135827d1db797 | 3f457dc939c94412bca13f40e8b2789e806cf40bfbe11d61b82c728f4765ec7b | [
{
"content": "In samples exposed to which compound is the ZNF318 gene upregulated?",
"role": "user"
},
{
"content": "ZNF318 is upregulated in samples exposed to Pitavastatin.",
"role": "assistant"
}
] | atomic_qa | train | d2dc45c539560be2c7a105711a7ce45a36a40657a8eaa0e0ce6876da7d6cbe03 | 1 | 1 | [
"Compound::DB08860",
"Gene::24149"
] | [
"d480b262ce66487bf14c19d2bdd03a06db7b15febeafdec48f77f78269634fb4"
] | [
{
"edge_id": "d480b262ce66487bf14c19d2bdd03a06db7b15febeafdec48f77f78269634fb4",
"source_id": "Compound::DB08860",
"source_name": "Pitavastatin",
"relation_id": "Compound-upregulates-Gene",
"target_id": "Gene::24149",
"target_name": "ZNF318"
}
] | [
"Compound::DB08860"
] | [
"Compound-upregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 19} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"Entrez Gene",
"LINCS L1000"
] | [
"CC BY-NC 4.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Gene::24149", "query_direction": "inverse", "structural_split_key": "809404dbdca21fcc099a3a8a77d9222746dadd764effedb9a9ef59e92a94d0c4"} |
36ac7e615a3bf42362e6311723d4dbdcdd1ec5e12b501d388199e9947aad48d0 | a6401f38e588c9cb55d2a5642ff0d5b12ad6257b9d60a17b95b0077a239e94fc | [
{
"content": "Which gene's expression is reduced by Temsirolimus?",
"role": "user"
},
{
"content": "Temsirolimus downregulates the PAICS gene.",
"role": "assistant"
}
] | atomic_qa | train | 6b681352a74140e2b87a24065aca6f521c7efcc9b9a564fb1d8387cc11061a6e | 1 | 1 | [
"Compound::DB06287",
"Gene::10606"
] | [
"612cbe175fbbd9ba86f51ed480070fcc5b305455c4d67d07a7c4dc9d24352926"
] | [
{
"edge_id": "612cbe175fbbd9ba86f51ed480070fcc5b305455c4d67d07a7c4dc9d24352926",
"source_id": "Compound::DB06287",
"source_name": "Temsirolimus",
"relation_id": "Compound-downregulates-Gene",
"target_id": "Gene::10606",
"target_name": "PAICS"
}
] | [
"Gene::10606"
] | [
"Compound-downregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 12} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"Entrez Gene",
"LINCS L1000"
] | [
"CC BY-NC 4.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Compound::DB06287", "query_direction": "forward", "structural_split_key": "f608abd3c9531dbc9e1bc9b32e13e60504cf36cda248996327070c1ac3d4287c"} |
826a2f07bb5feb499c181988a3f697acc64a6d75513d96d7ebd815064a306549 | d283f7e5375bd1060f8a21e842948bdf23f224f1e1e2f15073653301a07755c2 | [
{
"content": "What gene does SEMA4F evolutionarily covary with?",
"role": "user"
},
{
"content": "SEMA4F evolutionarily covaries with DDIT4.",
"role": "assistant"
}
] | atomic_qa | train | 6b9293d7c589c09c1aea42757ec2dd8cc427ce4fbafa9b5b3bd6964d20f99a93 | 1 | 1 | [
"Gene::10505",
"Gene::54541"
] | [
"17fa65087586afaf7104e22467d478b141d823b78c8aa8dc650869b3c74c9109"
] | [
{
"edge_id": "17fa65087586afaf7104e22467d478b141d823b78c8aa8dc650869b3c74c9109",
"source_id": "Gene::10505",
"source_name": "SEMA4F",
"relation_id": "Gene-covaries-Gene",
"target_id": "Gene::54541",
"target_name": "DDIT4"
}
] | [
"Gene::54541"
] | [
"Gene-covaries-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 12} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"ERC",
"Entrez Gene"
] | [
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Gene::10505", "query_direction": "forward", "structural_split_key": "2c0bd9331080d1f6574b009b6f689459626bc7aa068814d8768de49af1c182bc"} |
cd845fd8433de56aab3e09bee2248ef50d0fcf4ec40e593d007acf615e2ccaf2 | 4dbf58d4e82c63ab5a46b0d0db4ee574772696bb1ad186a86da91d2dd60f0e45 | [
{
"content": "Which gene's protein product physically interacts with the protein products of SORBS2?",
"role": "user"
},
{
"content": "The protein product of ABL2 physically interacts with the protein products of SORBS2.",
"role": "assistant"
}
] | atomic_qa | train | c31e5cb9963a0694eb3b93bf733c97ed8369e140050b841622d4b82f41fc7cc9 | 1 | 1 | [
"Gene::27",
"Gene::8470"
] | [
"9c9f805747f98682af18717edb6f40851a0cb0402093cfd4dddae61f219ffc57"
] | [
{
"edge_id": "9c9f805747f98682af18717edb6f40851a0cb0402093cfd4dddae61f219ffc57",
"source_id": "Gene::27",
"source_name": "ABL2",
"relation_id": "Gene-interacts-Gene",
"target_id": "Gene::8470",
"target_name": "SORBS2"
}
] | [
"Gene::27"
] | [
"Gene-interacts-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 25} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Entrez Gene",
"UNSPECIFIED"
] | [
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Gene::8470", "query_direction": "inverse", "structural_split_key": "4f46db007fc4601ab83311c54d2c1e419e860a314e97c2223fe877598571ea55"} |
3db4fd3b904b5d5b8f48c154718557bc386723635bc608d29f87838c67254e2a | bfa8540286f43c9ca7f220b487a2d836dec7f536509b5301a828650937da0f62 | [
{
"content": "Which compound causes ALDOC to be upregulated in samples?",
"role": "user"
},
{
"content": "Afatinib causes ALDOC to be upregulated in samples.",
"role": "assistant"
}
] | atomic_qa | train | cb7aa3415d54426da16c66682af04d7f8f4c5eace91e18d8771929d31d673675 | 1 | 1 | [
"Compound::DB08916",
"Gene::230"
] | [
"82d725126d7a68059b654b4f5d3cfc33bfb4791075ddfaa8107a5489d3240436"
] | [
{
"edge_id": "82d725126d7a68059b654b4f5d3cfc33bfb4791075ddfaa8107a5489d3240436",
"source_id": "Compound::DB08916",
"source_name": "Afatinib",
"relation_id": "Compound-upregulates-Gene",
"target_id": "Gene::230",
"target_name": "ALDOC"
}
] | [
"Compound::DB08916"
] | [
"Compound-upregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 17} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"Entrez Gene",
"LINCS L1000"
] | [
"CC BY-NC 4.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Gene::230", "query_direction": "inverse", "structural_split_key": "1ad38cf255345cbb282c56e568ececb30c1189e9859a74281059f3fb7317cbf1"} |
60f4fb2cbddfeb2edc0a89a05591fd15d7056186b24f41aff8f7883d4ea5a998 | 1edfac322b1b17f1205ca07e7d642516c3ec94951ebf19254f750c09db642ff2 | [
{
"content": "Which compound causes NR1H2 to be upregulated in samples?",
"role": "user"
},
{
"content": "Mitoxantrone.",
"role": "assistant"
}
] | atomic_qa | train | 2baa027e45f3806cdcdaecfea4142de3694d3ca6e682ee6df4c78cca45943436 | 1 | 1 | [
"Compound::DB01204",
"Gene::7376"
] | [
"87aa593c8c53d30442d720000278864dfb30de9b706037d51b2b1fc916a73ab4"
] | [
{
"edge_id": "87aa593c8c53d30442d720000278864dfb30de9b706037d51b2b1fc916a73ab4",
"source_id": "Compound::DB01204",
"source_name": "Mitoxantrone",
"relation_id": "Compound-upregulates-Gene",
"target_id": "Gene::7376",
"target_name": "NR1H2"
}
] | [
"Compound::DB01204"
] | [
"Compound-upregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 10} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"Entrez Gene",
"LINCS L1000"
] | [
"CC BY-NC 4.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Gene::7376", "query_direction": "inverse", "structural_split_key": "01bb3c2c9842ffdbb36fd91518b74ddbeeb0bcf46dd93582f4afa468165d92bb"} |
164b9e999ab112ce6ce63b86d4dd340a2d891b4cf1acfc63db6083c321b2ca1d | 5d87212cd75b0f3341bd5cebba277b66d2bcec2965c9094bdbccde15655689a1 | [
{
"content": "Which compound causes GRWD1 to be downregulated in samples?",
"role": "user"
},
{
"content": "Varenicline causes GRWD1 to be downregulated in samples.",
"role": "assistant"
}
] | atomic_qa | train | d5d3d968efae870862271a3ae9e02c18cdd6ac464701302b87dc6af2decefa8b | 1 | 1 | [
"Compound::DB01273",
"Gene::83743"
] | [
"51c2dbfb31eb80cbd33707c0eb9a89dbbaa374964325a0313dcf2662e70ebd4f"
] | [
{
"edge_id": "51c2dbfb31eb80cbd33707c0eb9a89dbbaa374964325a0313dcf2662e70ebd4f",
"source_id": "Compound::DB01273",
"source_name": "Varenicline",
"relation_id": "Compound-downregulates-Gene",
"target_id": "Gene::83743",
"target_name": "GRWD1"
}
] | [
"Compound::DB01273"
] | [
"Compound-downregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 17} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"Entrez Gene",
"LINCS L1000"
] | [
"CC BY-NC 4.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Gene::83743", "query_direction": "inverse", "structural_split_key": "be302fc789172caa44597308ee088a3c08401f6b9eeee6827b5595428a23f25a"} |
36eb9b0ebad2ab4983f2b515240139459ffba7862000d8a42faaa1008859dec7 | 931d47b7423d51a2959e272fbd84f10f611a99935dabd9b90b653e42d8aa1018 | [
{
"content": "Which compound is associated with the downregulation of DNAJC11 in exposed samples?",
"role": "user"
},
{
"content": "DNAJC11 is downregulated in samples exposed to Raloxifene.",
"role": "assistant"
}
] | atomic_qa | train | b5b8b3001f54a743457ab1f0a3237cea20f5b3fc96ee50d54c38a0e6b0f47234 | 1 | 1 | [
"Compound::DB00481",
"Gene::55735"
] | [
"664da1f89c1c7ade70577ed5a7d3ef4f8fafe73315423a6628f9391a0af70fa6"
] | [
{
"edge_id": "664da1f89c1c7ade70577ed5a7d3ef4f8fafe73315423a6628f9391a0af70fa6",
"source_id": "Compound::DB00481",
"source_name": "Raloxifene",
"relation_id": "Compound-downregulates-Gene",
"target_id": "Gene::55735",
"target_name": "DNAJC11"
}
] | [
"Compound::DB00481"
] | [
"Compound-downregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 20} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"Entrez Gene",
"LINCS L1000"
] | [
"CC BY-NC 4.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Gene::55735", "query_direction": "inverse", "structural_split_key": "900c566bae11806ed30664c2eba53583792a4d52086cbaabcc7bff3f18e69394"} |
538eb24be10b0e46518e09e6697230dd9515c9388f302bf8e8957356e708c932 | dcda6e917e692e72b551fa0969a951e068d047e82ad67e98a8ae9efd2e27d322 | [
{
"content": "What pharmacologic class does Cefazolin fall under?",
"role": "user"
},
{
"content": "Cefazolin belongs to the Cephalosporins pharmacologic class.",
"role": "assistant"
}
] | atomic_qa | train | 1aebc0a406a407ef66e3374e3bc870a86ade2320603ecedf88675369198de33f | 1 | 1 | [
"Pharmacologic Class::N0000011161",
"Compound::DB01327"
] | [
"9b2e534c6592aa0413d910e81f1e8d318fb21d2fecc447373d522938604ba3a5"
] | [
{
"edge_id": "9b2e534c6592aa0413d910e81f1e8d318fb21d2fecc447373d522938604ba3a5",
"source_id": "Pharmacologic Class::N0000011161",
"source_name": "Cephalosporins",
"relation_id": "Pharmacologic Class-includes-Compound",
"target_id": "Compound::DB01327",
"target_name": "Cefazolin"
}
] | [
"Pharmacologic Class::N0000011161"
] | [
"Pharmacologic Class-includes-Compound"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 14} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"DrugCentral",
"FDA via DrugCentral"
] | [
"CC BY 4.0",
"CC BY-NC 4.0"
] | {"known_id": "Compound::DB01327", "query_direction": "inverse", "structural_split_key": "d0128d9fa024957d1b330c11b5982d5a8c5b73f1d38c20536c5afcf56f4507cb"} |
99de3c59940ca4d26a097cc039c6c469e634729941a61d362a08e57f85e5dcb1 | 3c5a623a8c4e9e9a3ec984cbb9d64dfd841155f70e6dd7ddcce95db3b697c3df | [
{
"content": "In which compound-exposed samples is RNPEP upregulated?",
"role": "user"
},
{
"content": "RNPEP is upregulated in samples exposed to Mitoxantrone.",
"role": "assistant"
}
] | atomic_qa | train | 4eab129f764f27b5b7049787c902982a2b943310a63ca2ba12df35854aeb2ef2 | 1 | 1 | [
"Compound::DB01204",
"Gene::6051"
] | [
"5bc1a112a9420816e018469d91fd022da7039bb7700b5196d516abe979cb36af"
] | [
{
"edge_id": "5bc1a112a9420816e018469d91fd022da7039bb7700b5196d516abe979cb36af",
"source_id": "Compound::DB01204",
"source_name": "Mitoxantrone",
"relation_id": "Compound-upregulates-Gene",
"target_id": "Gene::6051",
"target_name": "RNPEP"
}
] | [
"Compound::DB01204"
] | [
"Compound-upregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 15} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"Entrez Gene",
"LINCS L1000"
] | [
"CC BY-NC 4.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Gene::6051", "query_direction": "inverse", "structural_split_key": "9b4f02a5a6e03602d9a270b026e85fad35e299819144b191c54482fd90c9808e"} |
48aa1f5cc3bcba718e91bc07f00c383d27dbdbd28732b4daa7cdd12f11e8581f | e7ec7d02a8706ffdadc074c5b1a96f828e90d33d3243919b7eff155471623da5 | [
{
"content": "Which gene is linked to prostate cancer?",
"role": "user"
},
{
"content": "GRB7",
"role": "assistant"
}
] | atomic_qa | train | 236b72d5cd7a18c57ef1a4288262e6f4cbc3116f6182a8a064322304725f2064 | 1 | 1 | [
"Disease::DOID:10283",
"Gene::2886"
] | [
"74745fc46c7afcaa95c33e1cdc56c1f217bbaa0bd9d851e9a49639243bbd4164"
] | [
{
"edge_id": "74745fc46c7afcaa95c33e1cdc56c1f217bbaa0bd9d851e9a49639243bbd4164",
"source_id": "Disease::DOID:10283",
"source_name": "prostate cancer",
"relation_id": "Disease-associates-Gene",
"target_id": "Gene::2886",
"target_name": "GRB7"
}
] | [
"Gene::2886"
] | [
"Disease-associates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 8} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"Entrez Gene",
"UNSPECIFIED"
] | [
"CC BY 3.0",
"CC0 1.0",
"ODbL 1.0"
] | {"known_id": "Disease::DOID:10283", "query_direction": "forward", "structural_split_key": "31558b3afcdedfff64b92b80c97901e1b9a265b74f13b10e492b0a22f04284db"} |
8942a8934ab54f49dad2b945a728d009d3cf2f3e0c2d368cabac77be23575b38 | 0011c6abc267795e3c1ffb31ff304b0dc0c5e34c6695a2038d29846a9084abb8 | [
{
"content": "What condition is NPAS2 linked to?",
"role": "user"
},
{
"content": "NPAS2 is linked to autistic disorder.",
"role": "assistant"
}
] | atomic_qa | train | f02bba2f280adebf292ba1e49a3f76708d24d3cac215fdf56434d5cea070fa11 | 1 | 1 | [
"Disease::DOID:12849",
"Gene::4862"
] | [
"46ef29ac1267b77f5bb74a8f03b6951536f40656ed66914b150ec18f36b9479c"
] | [
{
"edge_id": "46ef29ac1267b77f5bb74a8f03b6951536f40656ed66914b150ec18f36b9479c",
"source_id": "Disease::DOID:12849",
"source_name": "autistic disorder",
"relation_id": "Disease-associates-Gene",
"target_id": "Gene::4862",
"target_name": "NPAS2"
}
] | [
"Disease::DOID:12849"
] | [
"Disease-associates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 12} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"Entrez Gene",
"UNSPECIFIED"
] | [
"CC BY 3.0",
"CC0 1.0",
"ODbL 1.0"
] | {"known_id": "Gene::4862", "query_direction": "inverse", "structural_split_key": "cc9c7b533825c6d84466188a8cdef888562809693e43e02ecd68d4be81a239bb"} |
43d984e8a91ce4cece817a01fd91ec61b34b5737da6a84697b672b27e2bd8786 | c982955e2f760d4a59fcb2cdb325d5fd0f5af2b2756fe082d43adb5d68d43ab3 | [
{
"content": "Which gene is upregulated by exposure to Teniposide?",
"role": "user"
},
{
"content": "Exposure to Teniposide upregulates the IER3 gene.",
"role": "assistant"
}
] | atomic_qa | train | 0775a81d3103e39c7e5875ee542787a436676f30620cb48d93c026a9b88a9647 | 1 | 1 | [
"Compound::DB00444",
"Gene::8870"
] | [
"217f8cf8409bdb6bd1c4ffb6a03d9026edd2a5561af044c2855970d192603b08"
] | [
{
"edge_id": "217f8cf8409bdb6bd1c4ffb6a03d9026edd2a5561af044c2855970d192603b08",
"source_id": "Compound::DB00444",
"source_name": "Teniposide",
"relation_id": "Compound-upregulates-Gene",
"target_id": "Gene::8870",
"target_name": "IER3"
}
] | [
"Gene::8870"
] | [
"Compound-upregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 15} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"Entrez Gene",
"LINCS L1000"
] | [
"CC BY-NC 4.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Compound::DB00444", "query_direction": "forward", "structural_split_key": "41886a943e0d6488aed1332acbef52b34be5f727c038d9b3f2fd33af4108cfaa"} |
e122a007dc9ba6d208fdf5c1672964e6285523829304ed70510dc2f63202ba8a | d23f60e07f5544d0cf34b58f1c6092e62c615146018c445d5b0ff0969c11864d | [
{
"content": "Which gene is responsible for producing the protein that carries out the molecular function known as Rho guanyl-nucleotide exchange factor activity?",
"role": "user"
},
{
"content": "The gene KALRN produces the protein responsible for this molecular function.",
"role": "assistant"
... | atomic_qa | train | 58d78463bc826e6ecb56f5df9b5dc573b2b9736e1a2f4c91e4c33115e3cd4e71 | 1 | 1 | [
"Gene::8997",
"Molecular Function::GO:0005089"
] | [
"12c5cfec49bccb55fcd1571838ef316d819c75de12035b43e06322ba10e3eb61"
] | [
{
"edge_id": "12c5cfec49bccb55fcd1571838ef316d819c75de12035b43e06322ba10e3eb61",
"source_id": "Gene::8997",
"source_name": "KALRN",
"relation_id": "Gene-participates-Molecular Function",
"target_id": "Molecular Function::GO:0005089",
"target_name": "Rho guanyl-nucleotide exchange factor acti... | [
"Gene::8997"
] | [
"Gene-participates-Molecular Function"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 32} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Entrez Gene",
"Gene Ontology",
"NCBI gene2go"
] | [
"CC BY 4.0",
"CC0 1.0"
] | {"known_id": "Molecular Function::GO:0005089", "query_direction": "inverse", "structural_split_key": "4fea3b1ecba7fa78dba379f3e702bf02d4960d0c08d18e25352653fb4af46990"} |
eee24711ab214bdef557ef9449cc9292e0a325205299c601e04281be2d738d9b | 847206e96f58859b026ef718a8a685c87f4348b0829cc8ebe8da1a81319b2ed0 | [
{
"content": "Which gene shows evolutionary covariance with RASGRP1?",
"role": "user"
},
{
"content": "RAX2 shows evolutionary covariance with RASGRP1.",
"role": "assistant"
}
] | atomic_qa | train | b36a46d86f129a7703b45f56034f843e21cff31d1e6f1e652bc87cea762afa61 | 1 | 1 | [
"Gene::84839",
"Gene::10125"
] | [
"cd028b494833eceee7892096e5435714722441fbe28e35228c5e962e1d76a0a6"
] | [
{
"edge_id": "cd028b494833eceee7892096e5435714722441fbe28e35228c5e962e1d76a0a6",
"source_id": "Gene::84839",
"source_name": "RAX2",
"relation_id": "Gene-covaries-Gene",
"target_id": "Gene::10125",
"target_name": "RASGRP1"
}
] | [
"Gene::84839"
] | [
"Gene-covaries-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 13} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"ERC",
"Entrez Gene"
] | [
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Gene::10125", "query_direction": "inverse", "structural_split_key": "c2f1e070dd50a624f625a3584078c0ab2c6f6597fcb63a62e57830623a2355b6"} |
271215807685184c88dc4707d43b591c58c5c77e506571dd6029e05406352e1a | 2f33b4d1deebab1b6d409fd3f5db4272806bc41e243c9ac22fe6e500360e8b10 | [
{
"content": "What side effect can Aripiprazole cause?",
"role": "user"
},
{
"content": "Aripiprazole can cause blood cholesterol decreased.",
"role": "assistant"
}
] | atomic_qa | train | f3a56e503e3b6478b1a46ebe68654cf7a5b489c8c932f1af645f51ffb8ac8dc9 | 1 | 1 | [
"Compound::DB01238",
"Side Effect::C1536916"
] | [
"e152e5aff58958fdb4e7a1378b84cb58f43fb7a039453a29cea3cb9374d1d154"
] | [
{
"edge_id": "e152e5aff58958fdb4e7a1378b84cb58f43fb7a039453a29cea3cb9374d1d154",
"source_id": "Compound::DB01238",
"source_name": "Aripiprazole",
"relation_id": "Compound-causes-Side Effect",
"target_id": "Side Effect::C1536916",
"target_name": "Blood cholesterol decreased"
}
] | [
"Side Effect::C1536916"
] | [
"Compound-causes-Side Effect"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 12} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"SIDER 4.1",
"UMLS via SIDER 4.1"
] | [
"CC BY-NC 4.0",
"CC BY-NC-SA 4.0"
] | {"known_id": "Compound::DB01238", "query_direction": "forward", "structural_split_key": "09a764e77793d28f7aae95f0839e003cfaa79cf090baaec2a0369d21bac15332"} |
22e04284d383f93f5ffa6ccd303da040f5982964ce503ead7e38af3697e371cb | 87c2015fe6e0ecddc1a0d597a0fe72296e8d49cb35a63e55c4b3aca31d6b20a4 | [
{
"content": "In post-juvenile adult human samples, which gene shows lower expression in the adrenal cortex?",
"role": "user"
},
{
"content": "BNIPL shows lower expression in the adrenal cortex.",
"role": "assistant"
}
] | atomic_qa | train | c8051a79d78406b70d1b91f8ff3481b9ea0d70aed6ba15dab59ed7b1936c19fd | 1 | 1 | [
"Anatomy::UBERON:0001235",
"Gene::149428"
] | [
"4a8bd99e9a42bcac544078c10a2f29019a155e97bf7fa608cbb0fcd3d9437559"
] | [
{
"edge_id": "4a8bd99e9a42bcac544078c10a2f29019a155e97bf7fa608cbb0fcd3d9437559",
"source_id": "Anatomy::UBERON:0001235",
"source_name": "adrenal cortex",
"relation_id": "Anatomy-downregulates-Gene",
"target_id": "Gene::149428",
"target_name": "BNIPL"
}
] | [
"Gene::149428"
] | [
"Anatomy-downregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 22} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Bgee",
"Entrez Gene",
"Uberon"
] | [
"CC BY 3.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Anatomy::UBERON:0001235", "query_direction": "forward", "structural_split_key": "341a20c5bc35ee3adfeeb7175ea809dc50e71e103efc3b4b69f56e0b0165c387"} |
4a77004d5d14b08211b1baa0945995d544478481a7ee9ead4e3bcf9c98b8d9b1 | 13a9444b0fa83f57410ca62c746d892f813298a6b9c87c14d61b70b88bc3f422 | [
{
"content": "Which gene shows evolutionary covariance with FGF12?",
"role": "user"
},
{
"content": "NELFE shows evolutionary covariance with FGF12.",
"role": "assistant"
}
] | atomic_qa | train | b331b304be3ac26d2b756c005bb2150906682c189e9aa4ec44e314b3052d04b4 | 1 | 1 | [
"Gene::7936",
"Gene::2257"
] | [
"6f40a43214c9380bc6d0918aff4660156dfc1ab07b12e7468409c8426afc57a7"
] | [
{
"edge_id": "6f40a43214c9380bc6d0918aff4660156dfc1ab07b12e7468409c8426afc57a7",
"source_id": "Gene::7936",
"source_name": "NELFE",
"relation_id": "Gene-covaries-Gene",
"target_id": "Gene::2257",
"target_name": "FGF12"
}
] | [
"Gene::7936"
] | [
"Gene-covaries-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 13} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"ERC",
"Entrez Gene"
] | [
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Gene::2257", "query_direction": "inverse", "structural_split_key": "588e24703328050553e4ad831c5644b519e79f7e7777d5fd285944e107a7d390"} |
3857a48215a1b35e916982e63451b4cba1914fbe2a17f57a029892031c5e8393 | e0a8327bf616a8c5b1436283047c8aa45e638ff6c72abf7c92bd1cdbc282d8bc | [
{
"content": "Which gene produces the protein that Pyrimethamine binds to?",
"role": "user"
},
{
"content": "Pyrimethamine binds to the protein produced by the CYP2C8 gene.",
"role": "assistant"
}
] | atomic_qa | train | 05f831e82d93ca1a6083b3d735eb04f7fd6d2706ffbd55c06436455cae324ac0 | 1 | 1 | [
"Compound::DB00205",
"Gene::1558"
] | [
"0f84d9bde40c4a4084a67cd9d2359a912a1b28bc7b1ac56bd263865d329c25fd"
] | [
{
"edge_id": "0f84d9bde40c4a4084a67cd9d2359a912a1b28bc7b1ac56bd263865d329c25fd",
"source_id": "Compound::DB00205",
"source_name": "Pyrimethamine",
"relation_id": "Compound-binds-Gene",
"target_id": "Gene::1558",
"target_name": "CYP2C8"
}
] | [
"Gene::1558"
] | [
"Compound-binds-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 19} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"Entrez Gene",
"UNSPECIFIED"
] | [
"CC BY-NC 4.0",
"CC0 1.0"
] | {"known_id": "Compound::DB00205", "query_direction": "forward", "structural_split_key": "193cf4f4423e4a20e667b696fd18c0daab63e9d20a65120b8a5b1643b2428319"} |
dbdc912cf097546927ce1ce555d0fb5788dafb4ea88bfd674baf147bd03b1ccf | ce7d38d90f7244ce2920a7bca72149c1b5438cc24dd8196dd5aff8956ed548e9 | [
{
"content": "Which disease is linked to the SH2B3 gene?",
"role": "user"
},
{
"content": "The SH2B3 gene is linked to systemic lupus erythematosus.",
"role": "assistant"
}
] | atomic_qa | train | 991abf9bddc4ef97c83ba9ccad05ba7c8f2c62fd9691830ce93288961b0d27c1 | 1 | 1 | [
"Disease::DOID:9074",
"Gene::10019"
] | [
"8cf2f40959f4169a1d9c208d393b0d3b7bebfabe508ef472b54ba28af1948a68"
] | [
{
"edge_id": "8cf2f40959f4169a1d9c208d393b0d3b7bebfabe508ef472b54ba28af1948a68",
"source_id": "Disease::DOID:9074",
"source_name": "systemic lupus erythematosus",
"relation_id": "Disease-associates-Gene",
"target_id": "Gene::10019",
"target_name": "SH2B3"
}
] | [
"Disease::DOID:9074"
] | [
"Disease-associates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 17} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"Entrez Gene",
"UNSPECIFIED"
] | [
"CC BY 3.0",
"CC0 1.0",
"ODbL 1.0"
] | {"known_id": "Gene::10019", "query_direction": "inverse", "structural_split_key": "54d908b5e0f21e0e24d53421ab6ba7a51e620a8e146347a685998f7e367bf2cf"} |
1bf04c49d41cb4213a4102b25db31272b1fc5fe2d234c525c2ce369ed68781dc | 0be3a46d364cf8c301156249e2237bb2990e73e92b4937121e713194a8477290 | [
{
"content": "What compound is chemically similar to Phentermine?",
"role": "user"
},
{
"content": "Phentermine is chemically similar to Tranylcypromine.",
"role": "assistant"
}
] | atomic_qa | train | ea607c941dd7799f2e6dd22b62d1569b26d6ecd86b6da7a31f5730d6f0b312f9 | 1 | 1 | [
"Compound::DB00191",
"Compound::DB00752"
] | [
"8b88a24716e5f72104196c15d3b3c032e0add549d9b4f201d2faa3a1b57dfbb5"
] | [
{
"edge_id": "8b88a24716e5f72104196c15d3b3c032e0add549d9b4f201d2faa3a1b57dfbb5",
"source_id": "Compound::DB00191",
"source_name": "Phentermine",
"relation_id": "Compound-resembles-Compound",
"target_id": "Compound::DB00752",
"target_name": "Tranylcypromine"
}
] | [
"Compound::DB00752"
] | [
"Compound-resembles-Compound"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 13} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Dice similarity of ECFPs",
"DrugBank"
] | [
"CC BY-NC 4.0",
"CC0 1.0"
] | {"known_id": "Compound::DB00191", "query_direction": "forward", "structural_split_key": "1b7e432631b2f6aee2f3444a0d428f955a9735cd8110aa56a5d1891d1101afa9"} |
fb8c6d5c2b3cd2138ad57b4980a015493498c562d318763401e5058c70595956 | 3906defdb3e637a57c5b917e4240310f132fd8195c8e60abafd0fd9a07a2c363 | [
{
"content": "What molecular function does the product of C1S participate in?",
"role": "user"
},
{
"content": "The product of C1S participates in endopeptidase activity.",
"role": "assistant"
}
] | atomic_qa | train | 1ec558700486c8cfec54c5d14891be62f626a6149745733221d31d12e65e5b1b | 1 | 1 | [
"Gene::716",
"Molecular Function::GO:0004175"
] | [
"ec378806a4134216e30abec14f6ef6d1bf47cf07cb034a080bf8d4d602df616b"
] | [
{
"edge_id": "ec378806a4134216e30abec14f6ef6d1bf47cf07cb034a080bf8d4d602df616b",
"source_id": "Gene::716",
"source_name": "C1S",
"relation_id": "Gene-participates-Molecular Function",
"target_id": "Molecular Function::GO:0004175",
"target_name": "endopeptidase activity"
}
] | [
"Molecular Function::GO:0004175"
] | [
"Gene-participates-Molecular Function"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 18} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Entrez Gene",
"Gene Ontology",
"NCBI gene2go"
] | [
"CC BY 4.0",
"CC0 1.0"
] | {"known_id": "Gene::716", "query_direction": "forward", "structural_split_key": "92b8353281e90f8c3ef9d65a09fd15934873812b94952db833c7a4a96bba65d4"} |
17d66277afa604811358f26f78d7e19d9a419b17bef2a5d1602b883045818475 | f27e0551574ef06463249107d68447a0c1c97c168f216f57c1cbd804ff773f61 | [
{
"content": "What disease is APOA2 linked to?",
"role": "user"
},
{
"content": "APOA2 is associated with atherosclerosis.",
"role": "assistant"
}
] | atomic_qa | train | d9c752d1addaf2ec665b6410addebd5a46466d02d58ff842177ffe8b0f6d7cdd | 1 | 1 | [
"Disease::DOID:1936",
"Gene::336"
] | [
"f1c6a8b55bcd6dd9ea562800ad2ee367cb074481a0ef1105dfccbc935c6116bb"
] | [
{
"edge_id": "f1c6a8b55bcd6dd9ea562800ad2ee367cb074481a0ef1105dfccbc935c6116bb",
"source_id": "Disease::DOID:1936",
"source_name": "atherosclerosis",
"relation_id": "Disease-associates-Gene",
"target_id": "Gene::336",
"target_name": "APOA2"
}
] | [
"Disease::DOID:1936"
] | [
"Disease-associates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 11} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"Entrez Gene",
"UNSPECIFIED"
] | [
"CC BY 3.0",
"CC BY 4.0",
"CC0 1.0"
] | {"known_id": "Gene::336", "query_direction": "inverse", "structural_split_key": "2f3360e6a537f7cd27d916e9bf45df6d2c90f81f55979d3574b45179af3485f0"} |
e369c8f8ffd7f0413d5366f938e325275752e2d13ddf31bac9ca4de1e79f5c66 | d4471215560764838ad923f57b21a5318a981853dc2c0b08a002796b9a23e4e6 | [
{
"content": "Which compound is structurally similar to Aminohippurate?",
"role": "user"
},
{
"content": "Aminohippurate is structurally similar to Bezafibrate.",
"role": "assistant"
}
] | atomic_qa | train | f2c7cb1f15b7f1b6f0fdfb16f3270cf7d146f62d4fc3ac43591b36863fa45e2c | 1 | 1 | [
"Compound::DB01393",
"Compound::DB00345"
] | [
"64227f99872dc368d97f2117a619c02d0e3cfacfcaf4f20e1a7d75cbd7268f15"
] | [
{
"edge_id": "64227f99872dc368d97f2117a619c02d0e3cfacfcaf4f20e1a7d75cbd7268f15",
"source_id": "Compound::DB01393",
"source_name": "Bezafibrate",
"relation_id": "Compound-resembles-Compound",
"target_id": "Compound::DB00345",
"target_name": "Aminohippurate"
}
] | [
"Compound::DB01393"
] | [
"Compound-resembles-Compound"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 13} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Dice similarity of ECFPs",
"DrugBank"
] | [
"CC BY-NC 4.0",
"CC0 1.0"
] | {"known_id": "Compound::DB00345", "query_direction": "inverse", "structural_split_key": "23321ba2e58190ce7a81618123f6f226918137aa9e003a0f908c1d3921e3c385"} |
c3659e7d4d88c818820d6aba2e74cbe2a2384b88c98b20b958b60ee3929c6a2b | ab2f8057049ad85430d59a5f3ed9605a29b3b22736d6723f33c9631f3cac997a | [
{
"content": "What compound does Nandrolone decanoate structurally resemble?",
"role": "user"
},
{
"content": "Nandrolone decanoate structurally resembles Gestodene.",
"role": "assistant"
}
] | atomic_qa | train | be90f1fc0a76ed6a60bdc571164e0a2363f23290070c65a878e75771137dba33 | 1 | 1 | [
"Compound::DB06730",
"Compound::DB08804"
] | [
"04e6aeb106d7d70b8d01cb9417a0fdf77d674fe0567b37b1adca518580e7df50"
] | [
{
"edge_id": "04e6aeb106d7d70b8d01cb9417a0fdf77d674fe0567b37b1adca518580e7df50",
"source_id": "Compound::DB06730",
"source_name": "Gestodene",
"relation_id": "Compound-resembles-Compound",
"target_id": "Compound::DB08804",
"target_name": "Nandrolone decanoate"
}
] | [
"Compound::DB06730"
] | [
"Compound-resembles-Compound"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 12} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Dice similarity of ECFPs",
"DrugBank"
] | [
"CC BY-NC 4.0",
"CC0 1.0"
] | {"known_id": "Compound::DB08804", "query_direction": "inverse", "structural_split_key": "1123e5753917c7f8859e7b4239e5d0f045e25a00fd9c52d13c0bd9d9b964e8c4"} |
f8abccbc9cb2d579b750279666f2a02102d9ec647d2a72ac8c390c5dbb085a51 | df1c1b36260e119e0b480389bb1cead9a55e8d1fa507885aa00f67282ba3e31a | [
{
"content": "Which gene's expression is reduced by exposure to Gefitinib?",
"role": "user"
},
{
"content": "HSPA8",
"role": "assistant"
}
] | atomic_qa | train | 985deef4cd12d7b9d0898179078c95081ae81a814f61346b89ca0cc20bc87910 | 1 | 1 | [
"Compound::DB00317",
"Gene::3312"
] | [
"793be49f54e886ed12465bce46aab84d0b95737887bcb463edb1db2e9e506c73"
] | [
{
"edge_id": "793be49f54e886ed12465bce46aab84d0b95737887bcb463edb1db2e9e506c73",
"source_id": "Compound::DB00317",
"source_name": "Gefitinib",
"relation_id": "Compound-downregulates-Gene",
"target_id": "Gene::3312",
"target_name": "HSPA8"
}
] | [
"Gene::3312"
] | [
"Compound-downregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 10} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"Entrez Gene",
"LINCS L1000"
] | [
"CC BY-NC 4.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Compound::DB00317", "query_direction": "forward", "structural_split_key": "1ff7e210446b3a602a9bff78c4c76a85fdf545f339a8b94ec8b227b8a17e19c3"} |
2e24e009f9e4d27adf6298949dacdcee3be3a36bceb8fec1bae6dbcb1bdc480f | 2b314223f48a26c32b514c7743557e07167b551ba04c5e3acd8bc826f2ff23b8 | [
{
"content": "Which gene is downregulated by alopecia areata?",
"role": "user"
},
{
"content": "alopecia areata downregulates MAPRE3.",
"role": "assistant"
}
] | atomic_qa | train | 557c44d0ab5c72f87b5346c4900073418a2b32ed6babfb6429b361262c1cf0b1 | 1 | 1 | [
"Disease::DOID:986",
"Gene::22924"
] | [
"a931f5b685ca9f23a216aefa58ca701d304d060b10caf1724a01c54e3dc78835"
] | [
{
"edge_id": "a931f5b685ca9f23a216aefa58ca701d304d060b10caf1724a01c54e3dc78835",
"source_id": "Disease::DOID:986",
"source_name": "alopecia areata",
"relation_id": "Disease-downregulates-Gene",
"target_id": "Gene::22924",
"target_name": "MAPRE3"
}
] | [
"Gene::22924"
] | [
"Disease-downregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 11} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"Entrez Gene",
"STARGEO"
] | [
"CC BY 3.0",
"CC0 1.0"
] | {"known_id": "Disease::DOID:986", "query_direction": "forward", "structural_split_key": "a9f2a88b0cc4dfbd04421ecc50ba0bc134c3d8159e1167c0ffde1f35409becf8"} |
032d1ba9c96fcc34038a174a758fc03c37aaaf711a41b8f11b767a8198520906 | c9214d6d87f50154357a52bf44a84a55bcce166ae5c7977bdc127e761706fcc8 | [
{
"content": "In which part of the body is PDLIM5 over-expressed in post-juvenile adult human samples?",
"role": "user"
},
{
"content": "PDLIM5 is over-expressed in the saliva-secreting gland in post-juvenile adult human samples.",
"role": "assistant"
}
] | atomic_qa | train | 013b7c6ed0033d5d980ac81574beca2c1f8b95f14438c5ac101bf30b08a9f44a | 1 | 1 | [
"Anatomy::UBERON:0001044",
"Gene::10611"
] | [
"b37ed5b9e04b5038308b3108ee8d97086932ac4a2ec17ca4cad69065dfba24fe"
] | [
{
"edge_id": "b37ed5b9e04b5038308b3108ee8d97086932ac4a2ec17ca4cad69065dfba24fe",
"source_id": "Anatomy::UBERON:0001044",
"source_name": "saliva-secreting gland",
"relation_id": "Anatomy-upregulates-Gene",
"target_id": "Gene::10611",
"target_name": "PDLIM5"
}
] | [
"Anatomy::UBERON:0001044"
] | [
"Anatomy-upregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 26} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Bgee",
"Entrez Gene",
"Uberon"
] | [
"CC BY 3.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Gene::10611", "query_direction": "inverse", "structural_split_key": "5c334882cfa043364a7a33cf6442beaf84f2b78bd93d397a80567d59813602df"} |
7ebd21189b2584d294986650f93f763670cba53f559a0778607a7e55037e7435 | 55244bb2f3590cb8f4740b8296e12483197b69301edbe0a9acdac5d6d33c4572 | [
{
"content": "Which gene is linked to melanoma?",
"role": "user"
},
{
"content": "ITGB1",
"role": "assistant"
}
] | atomic_qa | train | 61c5d4561ec7cf0121e77d4efb3715af2f19936bbda067384c585aaa340112fd | 1 | 1 | [
"Disease::DOID:1909",
"Gene::3688"
] | [
"f1e4aa1e8464e0213f4e24fe32ee7d355b94d5726610637ee6889872ad7306a1"
] | [
{
"edge_id": "f1e4aa1e8464e0213f4e24fe32ee7d355b94d5726610637ee6889872ad7306a1",
"source_id": "Disease::DOID:1909",
"source_name": "melanoma",
"relation_id": "Disease-associates-Gene",
"target_id": "Gene::3688",
"target_name": "ITGB1"
}
] | [
"Gene::3688"
] | [
"Disease-associates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 7} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"Entrez Gene",
"UNSPECIFIED"
] | [
"CC BY 3.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Disease::DOID:1909", "query_direction": "forward", "structural_split_key": "8d7d41ff8eb7487c96aa290727eab5013901f107c2da2637a790ab06e0ddb3ef"} |
fb53ed0f240a8173a59d779315a6ed15ebd7ea48939bb38acc9a122459b30b59 | afbf6cfb6e46b1654bdf0eb3a711de97bf564bf99297cdf1640397f035d61222 | [
{
"content": "What disease is associated with SIRPG?",
"role": "user"
},
{
"content": "SIRPG is associated with type 1 diabetes mellitus.",
"role": "assistant"
}
] | atomic_qa | train | 4e4fe6639dcc2be7550c7c263d00f94eed7987c7953f4166611dc6387627b5ef | 1 | 1 | [
"Disease::DOID:9744",
"Gene::55423"
] | [
"7371887953aa17ed8303fccc525ccc0a56ca37186fc0cbc7c8fbfc196c2194cf"
] | [
{
"edge_id": "7371887953aa17ed8303fccc525ccc0a56ca37186fc0cbc7c8fbfc196c2194cf",
"source_id": "Disease::DOID:9744",
"source_name": "type 1 diabetes mellitus",
"relation_id": "Disease-associates-Gene",
"target_id": "Gene::55423",
"target_name": "SIRPG"
}
] | [
"Disease::DOID:9744"
] | [
"Disease-associates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 14} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"Entrez Gene",
"UNSPECIFIED"
] | [
"CC BY 3.0",
"CC BY 4.0",
"CC0 1.0"
] | {"known_id": "Gene::55423", "query_direction": "inverse", "structural_split_key": "6a03071b2167ff8105cd30217f3a57ddd3869ee219468c705ddff9e6506f34d3"} |
df84dc6f1bdfe4d4902ac8cc3f3d50e59687c6b498a57c0257daa0862cd30171 | a833e49bb0f0067d76be1cce76bb1af13cb1fcfaa912b1fc0992e011f6ab088c | [
{
"content": "What disease is linked to SLC1A3?",
"role": "user"
},
{
"content": "SLC1A3 is linked to amyotrophic lateral sclerosis.",
"role": "assistant"
}
] | atomic_qa | train | c9baeaeda0c56c4850c2a0b256598260bdd1bdbc63df3b31cdcdfc9ae260eabb | 1 | 1 | [
"Disease::DOID:332",
"Gene::6507"
] | [
"5c5d9b6a7380fd6ad9574e9a037e0f4b0de599f0aac79dd69757d0c8c33c0e7f"
] | [
{
"edge_id": "5c5d9b6a7380fd6ad9574e9a037e0f4b0de599f0aac79dd69757d0c8c33c0e7f",
"source_id": "Disease::DOID:332",
"source_name": "amyotrophic lateral sclerosis",
"relation_id": "Disease-associates-Gene",
"target_id": "Gene::6507",
"target_name": "SLC1A3"
}
] | [
"Disease::DOID:332"
] | [
"Disease-associates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 13} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"Entrez Gene",
"UNSPECIFIED"
] | [
"CC BY 3.0",
"CC BY 4.0",
"CC0 1.0"
] | {"known_id": "Gene::6507", "query_direction": "inverse", "structural_split_key": "ab44c4b6292dc8dffb343fafdfd90e57809364ebcd7ebc15dd18c480b3053def"} |
997d8426923b0326af11282a507ba9a94310953caa27c65c46c27497b2f49ed2 | 58c03fdc8b26d8f3c154fae17f20429753644f3767e2838e46b5922053678505 | [
{
"content": "In post-juvenile adult human samples, which gene shows lower expression in the myometrium?",
"role": "user"
},
{
"content": "C14orf105",
"role": "assistant"
}
] | atomic_qa | train | 7e366a90bc799f000c3da2b1a4cb0079434c705f4e2b014c2bbfbab37312a7dd | 1 | 1 | [
"Anatomy::UBERON:0001296",
"Gene::55195"
] | [
"df1b3f92a65ec41098b600bddf261e5eaa9f5bd834dbdb2c197236500f63472a"
] | [
{
"edge_id": "df1b3f92a65ec41098b600bddf261e5eaa9f5bd834dbdb2c197236500f63472a",
"source_id": "Anatomy::UBERON:0001296",
"source_name": "myometrium",
"relation_id": "Anatomy-downregulates-Gene",
"target_id": "Gene::55195",
"target_name": "C14orf105"
}
] | [
"Gene::55195"
] | [
"Anatomy-downregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 14} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Bgee",
"Entrez Gene",
"Uberon"
] | [
"CC BY 3.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Anatomy::UBERON:0001296", "query_direction": "forward", "structural_split_key": "24e7cff183ec8218e538752adbf9a1cec32df9c595a514bf0c56095578e220fc"} |
3ebb05a0d46d7687568a8498517189bde36ff762dab2448a089d4fcb35467da0 | 6cc1a9e3ca7e4f69003c070ece3f923205aceb65b2369b171a40415c8bca5680 | [
{
"content": "Which gene is downregulated by exposure to Lamivudine?",
"role": "user"
},
{
"content": "Exposure to Lamivudine downregulates the KDM3A gene.",
"role": "assistant"
}
] | atomic_qa | train | 9ef17ee9bde0045916f474a9cd05dea100d5b9d0b2a71420d008e4abddeb572a | 1 | 1 | [
"Compound::DB00709",
"Gene::55818"
] | [
"2236be63484ff74f7caa40da0212e9d797a2d0a66d50b0df95b58cfae58c0049"
] | [
{
"edge_id": "2236be63484ff74f7caa40da0212e9d797a2d0a66d50b0df95b58cfae58c0049",
"source_id": "Compound::DB00709",
"source_name": "Lamivudine",
"relation_id": "Compound-downregulates-Gene",
"target_id": "Gene::55818",
"target_name": "KDM3A"
}
] | [
"Gene::55818"
] | [
"Compound-downregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 15} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"Entrez Gene",
"LINCS L1000"
] | [
"CC BY-NC 4.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Compound::DB00709", "query_direction": "forward", "structural_split_key": "ba17c43f30af7289c2ed8342b08b6096f8ab09b96ce4a3c2d6748f1cdcdb53db"} |
2a0b23f2ce868376eb590799f260a938db47c99b77b4518b89e4f06b9fa2753f | d3bce2d245732475ecee00579f6e70f42f1becb5714b968b7a0afbaf2b29add5 | [
{
"content": "In which compound-exposed samples is the ALDOC gene upregulated?",
"role": "user"
},
{
"content": "ALDOC is upregulated in samples exposed to Daunorubicin.",
"role": "assistant"
}
] | atomic_qa | train | 666f8cf52e6d23a1b94909e5b98093c16b066132230f603e7e2f16f139d8ac21 | 1 | 1 | [
"Compound::DB00694",
"Gene::230"
] | [
"53b75e7d91bdeab1f8c310d99523d3a612db28a73861c536ec1ff76a7a68eb7e"
] | [
{
"edge_id": "53b75e7d91bdeab1f8c310d99523d3a612db28a73861c536ec1ff76a7a68eb7e",
"source_id": "Compound::DB00694",
"source_name": "Daunorubicin",
"relation_id": "Compound-upregulates-Gene",
"target_id": "Gene::230",
"target_name": "ALDOC"
}
] | [
"Compound::DB00694"
] | [
"Compound-upregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 17} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"Entrez Gene",
"LINCS L1000"
] | [
"CC BY-NC 4.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Gene::230", "query_direction": "inverse", "structural_split_key": "50b1bf03ad05830866ed4a4f71662e8263a0e05c66fbf771ad0cd1ebe863fb8a"} |
0b81f49ed36a5cdb06a01c80bddd1306f0b3ee4d4786e689b3427c9dfc4e3915 | 6466127a4ef914534ab30fa296c1b47ad3996b7ea079a13c8c5031a0e65b65ec | [
{
"content": "In which disease is the GRIP1 gene found to be under-expressed?",
"role": "user"
},
{
"content": "The GRIP1 gene is under-expressed in Barrett's esophagus.",
"role": "assistant"
}
] | atomic_qa | train | c9e2c28d931ff3229958a552f7bd61bb4c110e590dccb0d916c14885fee454e7 | 1 | 1 | [
"Disease::DOID:9206",
"Gene::23426"
] | [
"e247c24497ee1721947ba8f51ab85ea8d310c51d227979235b3ba99e731c1270"
] | [
{
"edge_id": "e247c24497ee1721947ba8f51ab85ea8d310c51d227979235b3ba99e731c1270",
"source_id": "Disease::DOID:9206",
"source_name": "Barrett's esophagus",
"relation_id": "Disease-downregulates-Gene",
"target_id": "Gene::23426",
"target_name": "GRIP1"
}
] | [
"Disease::DOID:9206"
] | [
"Disease-downregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 19} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"Entrez Gene",
"STARGEO"
] | [
"CC BY 3.0",
"CC0 1.0"
] | {"known_id": "Gene::23426", "query_direction": "inverse", "structural_split_key": "e1b5e216c97f8dc0d22b3c83bbc1250dd6e529fa277f5205870b4ce8d63bb8a3"} |
a192058b503a636130d900773678d26165bd38aa2e456a7f8d4988c3700548a8 | 8fc1abed41f0425039504f86f02732066000b42a59670cfbf7ed6c89c3ce7685 | [
{
"content": "Which gene's expression is increased by exposure to Dasatinib?",
"role": "user"
},
{
"content": "Exposure to Dasatinib upregulates the UBE2L6 gene.",
"role": "assistant"
}
] | atomic_qa | train | b015a5b4bd16230f2f006fd870a746f08de989a617cf6858027e78656006664a | 1 | 1 | [
"Compound::DB01254",
"Gene::9246"
] | [
"276b42983e18bef49fd5298721bc47858f9b7e9dd671e2b9d83e9944923dab83"
] | [
{
"edge_id": "276b42983e18bef49fd5298721bc47858f9b7e9dd671e2b9d83e9944923dab83",
"source_id": "Compound::DB01254",
"source_name": "Dasatinib",
"relation_id": "Compound-upregulates-Gene",
"target_id": "Gene::9246",
"target_name": "UBE2L6"
}
] | [
"Gene::9246"
] | [
"Compound-upregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 16} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"Entrez Gene",
"LINCS L1000"
] | [
"CC BY-NC 4.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Compound::DB01254", "query_direction": "forward", "structural_split_key": "dc2a10970d1751c5a4ec55f552e311987d562935cdc8f0c2f168ddfbb2840396"} |
3da4eb2ddfe3fe87377a0441442ae84e31ed5fa9fece292f93b0fd08c64342fd | 3375abd61b7cfe7f16a7e4edc87d9dea620448d6014fcec96d4d1e648d2b1b1e | [
{
"content": "Which gene's protein product is known to physically interact with the protein products of NACC2?",
"role": "user"
},
{
"content": "The protein products of NACC2 are known to physically interact with the protein products of EPS8.",
"role": "assistant"
}
] | atomic_qa | train | be97ceacbf30db5cf211617812ebaea10fae37f87e208c83584db118c52fb4ba | 1 | 1 | [
"Gene::2059",
"Gene::138151"
] | [
"2eb31946f0646c9b4d375b3fa2819d6b25502969b49541835321cf0d4b09eced"
] | [
{
"edge_id": "2eb31946f0646c9b4d375b3fa2819d6b25502969b49541835321cf0d4b09eced",
"source_id": "Gene::2059",
"source_name": "EPS8",
"relation_id": "Gene-interacts-Gene",
"target_id": "Gene::138151",
"target_name": "NACC2"
}
] | [
"Gene::2059"
] | [
"Gene-interacts-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 31} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Entrez Gene",
"UNSPECIFIED"
] | [
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Gene::138151", "query_direction": "inverse", "structural_split_key": "c00b63124e23e7014ae85d1ac545d89d0c3d264efd68d040a5ba91460a3bb810"} |
2fcb70af17ec88707ac6ef81c7dcc8b3d3aff55d1ee327c6c47a96280bdcf6a5 | 8fb228f26d21870a7f35205a96eb95cb7c58b5ba9d50c20341eaae39ef215e45 | [
{
"content": "What gene is upregulated in pancreatic cancer?",
"role": "user"
},
{
"content": "Pancreatic cancer upregulates CDC45.",
"role": "assistant"
}
] | atomic_qa | train | 3ecb9972e8341c2c96da7172ef3764e84df0cd33dc24d77fd5f599f267de29cc | 1 | 1 | [
"Disease::DOID:1793",
"Gene::8318"
] | [
"f3a2f99434de326b0a2caae30b99ae7478ea253b7161895140100ad4cb6a1bb2"
] | [
{
"edge_id": "f3a2f99434de326b0a2caae30b99ae7478ea253b7161895140100ad4cb6a1bb2",
"source_id": "Disease::DOID:1793",
"source_name": "pancreatic cancer",
"relation_id": "Disease-upregulates-Gene",
"target_id": "Gene::8318",
"target_name": "CDC45"
}
] | [
"Gene::8318"
] | [
"Disease-upregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 11} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"Entrez Gene",
"STARGEO"
] | [
"CC BY 3.0",
"CC0 1.0"
] | {"known_id": "Disease::DOID:1793", "query_direction": "forward", "structural_split_key": "b646895cc65c56b18070efc80def116b72cf8d66a5527eb9830cfc4eea8037cb"} |
0e33dcf607b6c6636427498367087dff87feecb485877e9722a1887ce2888813 | 5f1c1f1b7c1d2fb0582938eff6e2a66327aaab01702a34008cf58e99c42405c4 | [
{
"content": "Which gene is linked to celiac disease?",
"role": "user"
},
{
"content": "CD79A",
"role": "assistant"
}
] | atomic_qa | train | e107ad2f4fa3c5640a5f4de2b863a1b28745eefb6483b3e409529f41bb705dc6 | 1 | 1 | [
"Disease::DOID:10608",
"Gene::973"
] | [
"d4db55d8f851af8c37d00e7c5574da8af0d36a986cd274ec70dc2f0ef6cb25f9"
] | [
{
"edge_id": "d4db55d8f851af8c37d00e7c5574da8af0d36a986cd274ec70dc2f0ef6cb25f9",
"source_id": "Disease::DOID:10608",
"source_name": "celiac disease",
"relation_id": "Disease-associates-Gene",
"target_id": "Gene::973",
"target_name": "CD79A"
}
] | [
"Gene::973"
] | [
"Disease-associates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 8} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"Entrez Gene",
"UNSPECIFIED"
] | [
"CC BY 3.0",
"CC BY 4.0",
"CC0 1.0"
] | {"known_id": "Disease::DOID:10608", "query_direction": "forward", "structural_split_key": "4a549134df9ac7937882ec8a577476e20d75d3f882951d74b5a16e28849abf23"} |
acf1ddc5b510cfb8a14d867efd248f71b9569097986fedba20195d85b8f1aaf3 | 0afec3d4c5ae40eaafa0d33ce5302ca011d74875b127b17be02e13b2de6c3173 | [
{
"content": "What disease is NPM1 linked to?",
"role": "user"
},
{
"content": "NPM1 is linked to stomach cancer.",
"role": "assistant"
}
] | atomic_qa | train | e96b0a2b8d82b7944374113c1f44230949929c1a195970bbb53ace6f51cd4019 | 1 | 1 | [
"Disease::DOID:10534",
"Gene::4869"
] | [
"c50570c69c29183f00ec42124d654c558f821ae5a67cd28da26dd1fe0bdf27f3"
] | [
{
"edge_id": "c50570c69c29183f00ec42124d654c558f821ae5a67cd28da26dd1fe0bdf27f3",
"source_id": "Disease::DOID:10534",
"source_name": "stomach cancer",
"relation_id": "Disease-associates-Gene",
"target_id": "Gene::4869",
"target_name": "NPM1"
}
] | [
"Disease::DOID:10534"
] | [
"Disease-associates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 12} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"Entrez Gene",
"UNSPECIFIED"
] | [
"CC BY 3.0",
"CC0 1.0",
"ODbL 1.0"
] | {"known_id": "Gene::4869", "query_direction": "inverse", "structural_split_key": "cd7b81718a311244908794e472716913a5233c4d9bb4167e3f92cd08e94b9217"} |
6962988903a4e9bc782358c74d2bdc77339fc39d7e9501821ac2d7ea160169d5 | a42f030efea30017790aea16a863b96fa618c21852ee05908577ab0c0aba2cbe | [
{
"content": "Which gene shows evolutionary covariance with CCDC141?",
"role": "user"
},
{
"content": "PRR14L.",
"role": "assistant"
}
] | atomic_qa | train | a5bb2d64cd9786e84e7e151c4c92066e4302dec217697c96a2591933a4923cd3 | 1 | 1 | [
"Gene::253143",
"Gene::285025"
] | [
"167e473b21c5a9418f6d995b816d9fbc8a3fbcb686ead149f6b380b418d5bc2d"
] | [
{
"edge_id": "167e473b21c5a9418f6d995b816d9fbc8a3fbcb686ead149f6b380b418d5bc2d",
"source_id": "Gene::253143",
"source_name": "PRR14L",
"relation_id": "Gene-covaries-Gene",
"target_id": "Gene::285025",
"target_name": "CCDC141"
}
] | [
"Gene::253143"
] | [
"Gene-covaries-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 8} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"ERC",
"Entrez Gene"
] | [
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Gene::285025", "query_direction": "inverse", "structural_split_key": "403e736953831fe2fa0b0c68b1d2674504ad82491d2e20d714d7a9e16e7e34f8"} |
0b324d4e77a3c825dcb86e7d62354c70786f46ffee8cca307bb58d15eb43fc79 | 03c6da62a6d592632d022309e803065059b21e3a142daeb0b797a621727fdccc | [
{
"content": "Which gene produces the protein that L-Methionine binds to?",
"role": "user"
},
{
"content": "The protein that L-Methionine binds to is produced by the MTHFR gene.",
"role": "assistant"
}
] | atomic_qa | train | 6c5f95d547d21b6c20591e91c83e8cd677d5a977f307e1ca832f42b0335c8320 | 1 | 1 | [
"Compound::DB00134",
"Gene::4524"
] | [
"874299b210e6a1b8d3fe9d5362a165d61a25b5adf3e10dd829047cee4a264a76"
] | [
{
"edge_id": "874299b210e6a1b8d3fe9d5362a165d61a25b5adf3e10dd829047cee4a264a76",
"source_id": "Compound::DB00134",
"source_name": "L-Methionine",
"relation_id": "Compound-binds-Gene",
"target_id": "Gene::4524",
"target_name": "MTHFR"
}
] | [
"Gene::4524"
] | [
"Compound-binds-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 21} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"Entrez Gene",
"UNSPECIFIED"
] | [
"CC BY-NC 4.0",
"CC0 1.0"
] | {"known_id": "Compound::DB00134", "query_direction": "forward", "structural_split_key": "1e097767b7139f38ec598c3a83a79ae72a4185bbfff9f0840d0230718b43535c"} |
35f478c81c50b4954b643fabfb535be6bdd83adefa40b33dcdbfa5ea3994297d | 4a01d9a5516cedccc42a7e66ea4d0dede0e2705db2f518657d108a6544e290d7 | [
{
"content": "What disease can present with paralysis as a symptom?",
"role": "user"
},
{
"content": "Brain cancer.",
"role": "assistant"
}
] | atomic_qa | train | ec3356f354862300458d310fa7436bea8f8c3d090afe983ea02eec4c1ffec209 | 1 | 1 | [
"Disease::DOID:1319",
"Symptom::D010243"
] | [
"0545c311d54a9566cb7c60ee774ac9d6fb3cc515bafd05d1d1620741d8495e6d"
] | [
{
"edge_id": "0545c311d54a9566cb7c60ee774ac9d6fb3cc515bafd05d1d1620741d8495e6d",
"source_id": "Disease::DOID:1319",
"source_name": "brain cancer",
"relation_id": "Disease-presents-Symptom",
"target_id": "Symptom::D010243",
"target_name": "Paralysis"
}
] | [
"Disease::DOID:1319"
] | [
"Disease-presents-Symptom"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 11} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"MEDLINE cooccurrence",
"MeSH"
] | [
"CC BY 3.0",
"CC0 1.0"
] | {"known_id": "Symptom::D010243", "query_direction": "inverse", "structural_split_key": "59c401b1ee9debb0029c48556cb73bc5ae225fec2d52859d50465a3fc11bc591"} |
fb5782e6a341156053af5e8f6507fa984697a32ce955ae523a9e5e66adcf46f4 | dc124bcdb3b36ea55251f575e285a777bd78972010e88a5ed92f0069e86a917e | [
{
"content": "Which gene is downregulated by azoospermia?",
"role": "user"
},
{
"content": "CTDP1",
"role": "assistant"
}
] | atomic_qa | train | 193604b0ca665782ab09b7d99e4e66ce4adb484e51164d8464e3760f8160b3c5 | 1 | 1 | [
"Disease::DOID:14227",
"Gene::9150"
] | [
"551edf2b24c22996704f68fc68f93d9f6c4f1621a06b315a1fbb26a4cabafefd"
] | [
{
"edge_id": "551edf2b24c22996704f68fc68f93d9f6c4f1621a06b315a1fbb26a4cabafefd",
"source_id": "Disease::DOID:14227",
"source_name": "azoospermia",
"relation_id": "Disease-downregulates-Gene",
"target_id": "Gene::9150",
"target_name": "CTDP1"
}
] | [
"Gene::9150"
] | [
"Disease-downregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 7} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"Entrez Gene",
"STARGEO"
] | [
"CC BY 3.0",
"CC0 1.0"
] | {"known_id": "Disease::DOID:14227", "query_direction": "forward", "structural_split_key": "5854695d2d5f39e00d3c5eec77e1beb18783b9f61561af8f18407cbe26fc445b"} |
5439b4e6c116404afcd6e05a87212a8f99a4a6e6f5b778d3eea6d9e820379c47 | 1aecb302b53c869197e898ab74f8719b5abdf95c62af26b678ac43555f71a89c | [
{
"content": "What gene shows evolutionary covariance with ADAM21?",
"role": "user"
},
{
"content": "PLCD4",
"role": "assistant"
}
] | atomic_qa | train | c1e120ef215399bcf94849e9b8c6fd5d829dbb426588dde478304092eb8d05ca | 1 | 1 | [
"Gene::84812",
"Gene::8747"
] | [
"0f4718491a919d80464bf1c1d89ac2155440445cc16e18bce177300be2029f48"
] | [
{
"edge_id": "0f4718491a919d80464bf1c1d89ac2155440445cc16e18bce177300be2029f48",
"source_id": "Gene::84812",
"source_name": "PLCD4",
"relation_id": "Gene-covaries-Gene",
"target_id": "Gene::8747",
"target_name": "ADAM21"
}
] | [
"Gene::84812"
] | [
"Gene-covaries-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 8} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"ERC",
"Entrez Gene"
] | [
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Gene::8747", "query_direction": "inverse", "structural_split_key": "6c6c5482e08865ca07e50a63873ff4414109d5ab3a4001757445fc720086a31c"} |
e66b5e8072864bd2fccb27a708a5ba630f4bf31f39128871984ad768240eb998 | 4dad53c854e7c81003b546e55b3c51f12eb49275a8451d5cce3e8ba300b88ab1 | [
{
"content": "Which compound is Metaraminol chemically similar to?",
"role": "user"
},
{
"content": "Metaraminol is chemically similar to Phenylpropanolamine.",
"role": "assistant"
}
] | atomic_qa | train | b0d23e1c6fafde7c97954e84ebca75d6148818b364ecf706f61ac2f3644fbb30 | 1 | 1 | [
"Compound::DB00397",
"Compound::DB00610"
] | [
"ca6099e5b331c7d57ce11101f4b731a36ab518ddc512bc9408e79e36d71ea4fc"
] | [
{
"edge_id": "ca6099e5b331c7d57ce11101f4b731a36ab518ddc512bc9408e79e36d71ea4fc",
"source_id": "Compound::DB00397",
"source_name": "Phenylpropanolamine",
"relation_id": "Compound-resembles-Compound",
"target_id": "Compound::DB00610",
"target_name": "Metaraminol"
}
] | [
"Compound::DB00397"
] | [
"Compound-resembles-Compound"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 13} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Dice similarity of ECFPs",
"DrugBank"
] | [
"CC BY-NC 4.0",
"CC0 1.0"
] | {"known_id": "Compound::DB00610", "query_direction": "inverse", "structural_split_key": "c37828eeac300283b963e780a07c2f61ab8ef057a3a6888614e15d7063ebd607"} |
1d51bab4432f61d59b4388cbe12e942fc7118540a3a2739f2c45a1b0cde6d725 | ba044f0984e4fa305bb81b8e6db85f53a971488dd387699821f26e3ab2cb4b8e | [
{
"content": "Which gene's expression is reduced by Captopril exposure?",
"role": "user"
},
{
"content": "Captopril exposure reduces the expression of the ATF6 gene.",
"role": "assistant"
}
] | atomic_qa | train | 224cca18d5e6ff00a23d7dea22de6385ea91e2b9c9bff52a04b2324dad452444 | 1 | 1 | [
"Compound::DB01197",
"Gene::22926"
] | [
"c9b3368903e247fd6093fdbdab210a853969b2176a3fb1226503f94a32c8b47d"
] | [
{
"edge_id": "c9b3368903e247fd6093fdbdab210a853969b2176a3fb1226503f94a32c8b47d",
"source_id": "Compound::DB01197",
"source_name": "Captopril",
"relation_id": "Compound-downregulates-Gene",
"target_id": "Gene::22926",
"target_name": "ATF6"
}
] | [
"Gene::22926"
] | [
"Compound-downregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 17} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"Entrez Gene",
"LINCS L1000"
] | [
"CC BY-NC 4.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Compound::DB01197", "query_direction": "forward", "structural_split_key": "c197637e59c4b5d83dcc6efa1d4c73490c5061d82712c8d7725d6d1edefd2963"} |
1da9b596c5d7d26ea01668d01bb99601068a2312cfe78e01474328cecec641c8 | 9e245c39fe766901e53393ac07ec7acbda2daf42323e5a8bdf63b10efd3a821e | [
{
"content": "Which gene is downregulated by malaria?",
"role": "user"
},
{
"content": "malaria downregulates DTD2.",
"role": "assistant"
}
] | atomic_qa | train | 91da7da3a724980a52a843499c2044488bbdcc8d21b3430526b533c4578cbd97 | 1 | 1 | [
"Disease::DOID:12365",
"Gene::112487"
] | [
"0249f92abf0726da2d4123657e7c25a1e37ddb109409c967b579a746fde8a7ee"
] | [
{
"edge_id": "0249f92abf0726da2d4123657e7c25a1e37ddb109409c967b579a746fde8a7ee",
"source_id": "Disease::DOID:12365",
"source_name": "malaria",
"relation_id": "Disease-downregulates-Gene",
"target_id": "Gene::112487",
"target_name": "DTD2"
}
] | [
"Gene::112487"
] | [
"Disease-downregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 9} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"Entrez Gene",
"STARGEO"
] | [
"CC BY 3.0",
"CC0 1.0"
] | {"known_id": "Disease::DOID:12365", "query_direction": "forward", "structural_split_key": "8449db1239c0522a6d5bae368791c13737ec57899afa22eb91f36ec6b257a77f"} |
6b821c58a1e9595fe9dea14c581ee9b3c276b7af475845f4076e07a843911eb9 | 297c77098cb4c809a1fb0f57a5cc18db837fadec5f6e09e0fd9e54258fb4cc6c | [
{
"content": "Which gene is upregulated by polycystic ovary syndrome?",
"role": "user"
},
{
"content": "Polycystic ovary syndrome upregulates DEFB119.",
"role": "assistant"
}
] | atomic_qa | train | cdec7a3af03c1ddc2d08fff4dffee89a37fdf9aa4d8af765fc329839c5c38341 | 1 | 1 | [
"Disease::DOID:11612",
"Gene::245932"
] | [
"5eab69825a236b78699dbe23a05b3f4aa6b13357f751efdcb16b3aa1f9730808"
] | [
{
"edge_id": "5eab69825a236b78699dbe23a05b3f4aa6b13357f751efdcb16b3aa1f9730808",
"source_id": "Disease::DOID:11612",
"source_name": "polycystic ovary syndrome",
"relation_id": "Disease-upregulates-Gene",
"target_id": "Gene::245932",
"target_name": "DEFB119"
}
] | [
"Gene::245932"
] | [
"Disease-upregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 13} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"Entrez Gene",
"STARGEO"
] | [
"CC BY 3.0",
"CC0 1.0"
] | {"known_id": "Disease::DOID:11612", "query_direction": "forward", "structural_split_key": "eca7d1f6751616fa4d44abb9b1ff7d97ba8509756ea98d6416eef3165f722c1b"} |
c4f35efd3b1b6dc7c1fecbe66b4d3312f6a7adfd81ab1c44f7470d76d21b7bb7 | f42165c8da88a1543338dcb9d0bfc08583a4b65706abce912e882e1c9e807437 | [
{
"content": "What gene is downregulated by exposure to Methyldopa?",
"role": "user"
},
{
"content": "Exposure to Methyldopa downregulates the ERBB3 gene.",
"role": "assistant"
}
] | atomic_qa | train | 51461e331f2b6cde21049be3de12752b36f7099ca0f5186b996f776c21768c97 | 1 | 1 | [
"Compound::DB00968",
"Gene::2065"
] | [
"fddca36adbd46b83f956e40456dbca5ac0431ec2ba4d300f60ef4b03625ed709"
] | [
{
"edge_id": "fddca36adbd46b83f956e40456dbca5ac0431ec2ba4d300f60ef4b03625ed709",
"source_id": "Compound::DB00968",
"source_name": "Methyldopa",
"relation_id": "Compound-downregulates-Gene",
"target_id": "Gene::2065",
"target_name": "ERBB3"
}
] | [
"Gene::2065"
] | [
"Compound-downregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 15} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"Entrez Gene",
"LINCS L1000"
] | [
"CC BY-NC 4.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Compound::DB00968", "query_direction": "forward", "structural_split_key": "213a9fdba884e5e1f59697db76651ed03f2e4ca43d286eee05f7265f1183a26a"} |
75c21fc4b03f95f4d0d6fa613eb66d6178069836acfd5bbc7466b1030b6f3b3c | 8570b277f756601d9622163232fb4c689f0dcfb1f1952c044a768f3571ed84aa | [
{
"content": "Which gene's product is responsible for the molecular function known as chemokine activity?",
"role": "user"
},
{
"content": "The gene responsible for chemokine activity is CCL25.",
"role": "assistant"
}
] | atomic_qa | train | 254961f558d2ae7e90fc9ff61634b73166d7d7cbb70a7bc540e5a6f62eb10349 | 1 | 1 | [
"Gene::6370",
"Molecular Function::GO:0008009"
] | [
"44bbfae27f4b065bc541da5a81f73cabf1eb2c98d35140cd74342eda7dc8d346"
] | [
{
"edge_id": "44bbfae27f4b065bc541da5a81f73cabf1eb2c98d35140cd74342eda7dc8d346",
"source_id": "Gene::6370",
"source_name": "CCL25",
"relation_id": "Gene-participates-Molecular Function",
"target_id": "Molecular Function::GO:0008009",
"target_name": "chemokine activity"
}
] | [
"Gene::6370"
] | [
"Gene-participates-Molecular Function"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 21} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Entrez Gene",
"Gene Ontology",
"NCBI gene2go"
] | [
"CC BY 4.0",
"CC0 1.0"
] | {"known_id": "Molecular Function::GO:0008009", "query_direction": "inverse", "structural_split_key": "68bbee2797621c65f94147733be413519c36b7c1bc40de8a78cb672f7fb3c7cb"} |
78951c80ffe2d276ffffac06d00d4e5f06197136a1a716009782062a821befc6 | 09e31e69101df11bae2db9e42012b93c5aedabf10809d194ada91fb2e753d4e3 | [
{
"content": "Which gene is downregulated by multiple sclerosis?",
"role": "user"
},
{
"content": "Multiple sclerosis downregulates the MAPK1 gene.",
"role": "assistant"
}
] | atomic_qa | train | 19b4966aef4c14a91c538a6e2ec355b9da2db2d0385f45ff84dfe606f224c9a9 | 1 | 1 | [
"Disease::DOID:2377",
"Gene::5594"
] | [
"36567add068a0fa23493ba31cabc612960bf6552350b55f06472a34ef9f7acd4"
] | [
{
"edge_id": "36567add068a0fa23493ba31cabc612960bf6552350b55f06472a34ef9f7acd4",
"source_id": "Disease::DOID:2377",
"source_name": "multiple sclerosis",
"relation_id": "Disease-downregulates-Gene",
"target_id": "Gene::5594",
"target_name": "MAPK1"
}
] | [
"Gene::5594"
] | [
"Disease-downregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 13} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"Entrez Gene",
"STARGEO"
] | [
"CC BY 3.0",
"CC0 1.0"
] | {"known_id": "Disease::DOID:2377", "query_direction": "forward", "structural_split_key": "5909ef57ac93f8d037052b73200cd5d359bf99f7095837d8cd5664870497b388"} |
d1b3e33c439a11e2239d5806052ca82ccf1f82c1b647e33c7351ffe096f1759b | f5fd33d06ee01de9036e1a7500f98c24de8f898061265b3621b98483b298ecec | [
{
"content": "Which compound is associated with the upregulation of SPP1 in exposed samples?",
"role": "user"
},
{
"content": "SPP1 is upregulated in samples exposed to Raloxifene.",
"role": "assistant"
}
] | atomic_qa | train | b26a5febac37e06881ac4ae286d5fd14145f84f2adbae7ae717b2475f3dc81a4 | 1 | 1 | [
"Compound::DB00481",
"Gene::6696"
] | [
"3510e6d32827516f3de90d7ed429115578ad7f3b6b3566cf0402664f7b85eb14"
] | [
{
"edge_id": "3510e6d32827516f3de90d7ed429115578ad7f3b6b3566cf0402664f7b85eb14",
"source_id": "Compound::DB00481",
"source_name": "Raloxifene",
"relation_id": "Compound-upregulates-Gene",
"target_id": "Gene::6696",
"target_name": "SPP1"
}
] | [
"Compound::DB00481"
] | [
"Compound-upregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 20} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"Entrez Gene",
"LINCS L1000"
] | [
"CC BY-NC 4.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Gene::6696", "query_direction": "inverse", "structural_split_key": "c724df96a5e51ea0ab2ca3e67ee51f915c13ddab0f9f5a07bf49de8d7b495e78"} |
1f717d9b4dcf6f87f07ab458bfdae459af68cd809b71ffe0bdc9b8df3629ad2d | 1ee748be279b5c2a9c69de29956e54f0f61ce5fefbfb1cdfde9dd2ef65998cbe | [
{
"content": "In which compound's presence is HLA-DMA upregulated?",
"role": "user"
},
{
"content": "HLA-DMA is upregulated in the presence of Spironolactone.",
"role": "assistant"
}
] | atomic_qa | train | beb3fe036eba8fc5ff58881a2b8970679320e57561944b7ddc5b3b198372251c | 1 | 1 | [
"Compound::DB00421",
"Gene::3108"
] | [
"fa085b9df5986238e26798f56b78f34e3abf156d8b90a24c4a362fbb4dc4af28"
] | [
{
"edge_id": "fa085b9df5986238e26798f56b78f34e3abf156d8b90a24c4a362fbb4dc4af28",
"source_id": "Compound::DB00421",
"source_name": "Spironolactone",
"relation_id": "Compound-upregulates-Gene",
"target_id": "Gene::3108",
"target_name": "HLA-DMA"
}
] | [
"Compound::DB00421"
] | [
"Compound-upregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 15} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"Entrez Gene",
"LINCS L1000"
] | [
"CC BY-NC 4.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Gene::3108", "query_direction": "inverse", "structural_split_key": "5b30f474122c04259fb274e439948650a0a9b94bddfe8686661cb0aabff39fc4"} |
d6e31af728411c14e3409379a88ad97b5fe2348ab609ee6acbd7e9aea6693df9 | 918d5a59b3f176224e4f1e3dd03c4d6db26ec2bcb8ef2bce5edb1f96164ea004 | [
{
"content": "What gene does AQP12B evolutionarily covary with?",
"role": "user"
},
{
"content": "AQP12B evolutionarily covaries with SMCR8.",
"role": "assistant"
}
] | atomic_qa | train | 75e6c6fc550e94984e1c090ec43fff9c844ccf7475639f7bcf20a2b4467b5f8b | 1 | 1 | [
"Gene::653437",
"Gene::140775"
] | [
"f44a77d47902c5d662694a8dbc26d5919d07e4d0bf63866b41d4a96224e34ea7"
] | [
{
"edge_id": "f44a77d47902c5d662694a8dbc26d5919d07e4d0bf63866b41d4a96224e34ea7",
"source_id": "Gene::653437",
"source_name": "AQP12B",
"relation_id": "Gene-covaries-Gene",
"target_id": "Gene::140775",
"target_name": "SMCR8"
}
] | [
"Gene::140775"
] | [
"Gene-covaries-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 12} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"ERC",
"Entrez Gene"
] | [
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Gene::653437", "query_direction": "forward", "structural_split_key": "4b09bf80fe1a97e18ead6e87f512a62c987a622a3b6b30d2ee035191ef862414"} |
f9bb9ee465d5e532cd3c846964105e1ed47d4e5baa0a8c8448e7aed6449f39ff | 2200406bfe6ae855d7713a8e66db8348e37d3a4ec59091a2b78c09987304587b | [
{
"content": "Which compound helps relieve migraine symptoms?",
"role": "user"
},
{
"content": "Dihydroergotamine helps relieve migraine symptoms.",
"role": "assistant"
}
] | atomic_qa | train | e9a9abe8f4eaa90dc5cc694ce5e683e197df2a7c371934aa35bf1d8b198c8640 | 1 | 1 | [
"Compound::DB00320",
"Disease::DOID:6364"
] | [
"6be57b746f97997397eb7c5c59c0059469f4bc047d2e463ff20111a14de648b6"
] | [
{
"edge_id": "6be57b746f97997397eb7c5c59c0059469f4bc047d2e463ff20111a14de648b6",
"source_id": "Compound::DB00320",
"source_name": "Dihydroergotamine",
"relation_id": "Compound-palliates-Disease",
"target_id": "Disease::DOID:6364",
"target_name": "migraine"
}
] | [
"Compound::DB00320"
] | [
"Compound-palliates-Disease"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 11} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"DrugBank",
"PharmacotherapyDB"
] | [
"CC BY 3.0",
"CC BY-NC 4.0",
"CC0 1.0"
] | {"known_id": "Disease::DOID:6364", "query_direction": "inverse", "structural_split_key": "35d89f72884dfbcbcbb9f4587d4b083cc57df0bd298a5bd88d93f6934669fab0"} |
f9d77d41b91683abc81be1ffcee05823724feab0123f26e57ade87fe0a43161f | 16154f886e66652deb1356aefecd2d8bc2a528b0be007ea7fe77564d670454fb | [
{
"content": "Which gene is linked to breast cancer?",
"role": "user"
},
{
"content": "E2F1 is the gene associated with breast cancer.",
"role": "assistant"
}
] | atomic_qa | train | f59d59fccdc6870c0db9ab96130fd236d8a8be6af444624faf62b58fcf35ae36 | 1 | 1 | [
"Disease::DOID:1612",
"Gene::1869"
] | [
"095d650449c4a271ef01cacc16f46538e7c01275b9c9aee93f75e4cccf0a5c95"
] | [
{
"edge_id": "095d650449c4a271ef01cacc16f46538e7c01275b9c9aee93f75e4cccf0a5c95",
"source_id": "Disease::DOID:1612",
"source_name": "breast cancer",
"relation_id": "Disease-associates-Gene",
"target_id": "Gene::1869",
"target_name": "E2F1"
}
] | [
"Gene::1869"
] | [
"Disease-associates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 15} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"Entrez Gene",
"UNSPECIFIED"
] | [
"CC BY 3.0",
"CC0 1.0",
"ODbL 1.0"
] | {"known_id": "Disease::DOID:1612", "query_direction": "forward", "structural_split_key": "fc7d0b7c882da1da0a1bcf166d576882ca6f6f75efa6c9af070028cd283de6e3"} |
117cc408a9cb8e21ac4ec5a7855532f13adfdd3e9019b896c1157e5a869a8022 | 4576645853130ee98341d7cc725534213f02924e98c70aa73cc9f029aadb0f1d | [
{
"content": "Which gene's protein product does Paliperidone bind to?",
"role": "user"
},
{
"content": "Paliperidone binds the protein product of HTR2C.",
"role": "assistant"
}
] | atomic_qa | train | adc08b94e9c52830dbf07d932cbb4f2a541cb801f2b92f5bcc2c2ba0ce74871e | 1 | 1 | [
"Compound::DB01267",
"Gene::3358"
] | [
"e02a6ff85c69f1c7134d4cd53da0f87e9a77d4906117a8a2d3dd4f1026703678"
] | [
{
"edge_id": "e02a6ff85c69f1c7134d4cd53da0f87e9a77d4906117a8a2d3dd4f1026703678",
"source_id": "Compound::DB01267",
"source_name": "Paliperidone",
"relation_id": "Compound-binds-Gene",
"target_id": "Gene::3358",
"target_name": "HTR2C"
}
] | [
"Gene::3358"
] | [
"Compound-binds-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 15} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"Entrez Gene",
"UNSPECIFIED"
] | [
"CC BY-NC 4.0",
"CC0 1.0"
] | {"known_id": "Compound::DB01267", "query_direction": "forward", "structural_split_key": "04ce4931148ca355c7db40daaeae6d3b6e30ecaa1f77e34079d19757dc6f4cbb"} |
473a42ec561f197199b7866cb7e3952417710a5563d9caea827b3e9fc25670f5 | a498e8a06756bc291e5858a3412a90f5e6dcaf2f065059c8d5db2fb2f7fcc5a7 | [
{
"content": "What gene is upregulated by exposure to Ouabain?",
"role": "user"
},
{
"content": "Exposure to Ouabain upregulates the CFLAR gene.",
"role": "assistant"
}
] | atomic_qa | train | 19f8a0411b4775c0af793da1ecd29180ec7c6767a16663b8245fe2170ce88acc | 1 | 1 | [
"Compound::DB01092",
"Gene::8837"
] | [
"d35a10d2eac49348b21046438c3ee2189bf2b9a20be21f8a3a14d2d5d3d86d79"
] | [
{
"edge_id": "d35a10d2eac49348b21046438c3ee2189bf2b9a20be21f8a3a14d2d5d3d86d79",
"source_id": "Compound::DB01092",
"source_name": "Ouabain",
"relation_id": "Compound-upregulates-Gene",
"target_id": "Gene::8837",
"target_name": "CFLAR"
}
] | [
"Gene::8837"
] | [
"Compound-upregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 15} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"Entrez Gene",
"LINCS L1000"
] | [
"CC BY-NC 4.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Compound::DB01092", "query_direction": "forward", "structural_split_key": "b60d7993c29a77f0fcc173f8bafb5001345febd37b4f3164b0825654050fe910"} |
6f5df0fd5afa849505272ea6e918332b1ecbc4628cec20b3f7b98a558337c2ec | 1fc894a697f1e14dec77618c86be76e1917552934bf0e7ff23f4fa5cd70de4ea | [
{
"content": "Which gene is downregulated in kidney cancer?",
"role": "user"
},
{
"content": "ADK is the gene that is downregulated in kidney cancer.",
"role": "assistant"
}
] | atomic_qa | train | 15c9e491e2a83f3a54f923acd3d169acb18dc7eed59675d671faa588bda46626 | 1 | 1 | [
"Disease::DOID:263",
"Gene::132"
] | [
"bec99f4082f0b98766ccdefb0d4c45348aa029f4860420ea9728534a1bf927dc"
] | [
{
"edge_id": "bec99f4082f0b98766ccdefb0d4c45348aa029f4860420ea9728534a1bf927dc",
"source_id": "Disease::DOID:263",
"source_name": "kidney cancer",
"relation_id": "Disease-downregulates-Gene",
"target_id": "Gene::132",
"target_name": "ADK"
}
] | [
"Gene::132"
] | [
"Disease-downregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 17} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"Entrez Gene",
"STARGEO"
] | [
"CC BY 3.0",
"CC0 1.0"
] | {"known_id": "Disease::DOID:263", "query_direction": "forward", "structural_split_key": "35686a0fe94ae2fcfd4884cdcdbbe0fe732533d22605db03b7850b6ce5e66551"} |
d66a6238767da6326c613ef84c666ef83915ef205928aed5677b9ba1fdfe09da | 2f23e6da9db791be1dc472ac1bdc35e4914324b66649720482e705dd17c88e4d | [
{
"content": "What condition does Dextroamphetamine help relieve symptoms for?",
"role": "user"
},
{
"content": "Dextroamphetamine helps relieve symptoms of attention deficit hyperactivity disorder.",
"role": "assistant"
}
] | atomic_qa | train | 66461e19a3de5c2415c68254681bcd0020079ad1d460a6a3d39c25ca64050df6 | 1 | 1 | [
"Compound::DB01576",
"Disease::DOID:1094"
] | [
"de7b4a93cd6d7fa55a82d34bf0f9ddb2d2d163704ec89a641062bb8cbb6bfc55"
] | [
{
"edge_id": "de7b4a93cd6d7fa55a82d34bf0f9ddb2d2d163704ec89a641062bb8cbb6bfc55",
"source_id": "Compound::DB01576",
"source_name": "Dextroamphetamine",
"relation_id": "Compound-palliates-Disease",
"target_id": "Disease::DOID:1094",
"target_name": "attention deficit hyperactivity disorder"
}... | [
"Disease::DOID:1094"
] | [
"Compound-palliates-Disease"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 17} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"DrugBank",
"PharmacotherapyDB"
] | [
"CC BY 3.0",
"CC BY-NC 4.0",
"CC0 1.0"
] | {"known_id": "Compound::DB01576", "query_direction": "forward", "structural_split_key": "41606503efcf56d2fa585628886c7309dd421627ab502b47c27276b2c20ec7e8"} |
72cbc7d43a9a86333817b23cf04c788f3f5894e57c520c639eecf21840cf60a9 | f7db92b30c0a3d736715d1140c9c833d6baaea0c20338882bb8256661b11dd7c | [
{
"content": "What biological process is the product of CRTC2 involved in?",
"role": "user"
},
{
"content": "The product of CRTC2 is involved in the regulation of sequence-specific DNA binding transcription factor activity.",
"role": "assistant"
}
] | atomic_qa | train | 0ada82d1446b7aa4acb8b6a5563026096f436c9c047ee70326a0d408e34cdd82 | 1 | 1 | [
"Gene::200186",
"Biological Process::GO:0051090"
] | [
"89d4673690230dfc7eb43ce6d41101c8f6a93430326977dd0ca0127ed1ef5573"
] | [
{
"edge_id": "89d4673690230dfc7eb43ce6d41101c8f6a93430326977dd0ca0127ed1ef5573",
"source_id": "Gene::200186",
"source_name": "CRTC2",
"relation_id": "Gene-participates-Biological Process",
"target_id": "Biological Process::GO:0051090",
"target_name": "regulation of sequence-specific DNA bind... | [
"Biological Process::GO:0051090"
] | [
"Gene-participates-Biological Process"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 26} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Entrez Gene",
"Gene Ontology",
"NCBI gene2go"
] | [
"CC BY 4.0",
"CC0 1.0"
] | {"known_id": "Gene::200186", "query_direction": "forward", "structural_split_key": "09e5fa7494571e6aabcb8bf37325427e17713d31ca572710aa7ae3b3d072fbc6"} |
b6303aa2cfd88e93fe8f1871efbce14743ca9c8ab799b33018bbd562e65a2514 | fedf2b6c899baa111e565048ac07d3399cb43a0637070961561e973f6b51cdee | [
{
"content": "What disease is GDF15 associated with?",
"role": "user"
},
{
"content": "GDF15 is associated with anemia.",
"role": "assistant"
}
] | atomic_qa | train | 8a84e33c301a165f74ed46a9f444eeb290aac22698ed7b72b35ce7fa7cde9145 | 1 | 1 | [
"Disease::DOID:2355",
"Gene::9518"
] | [
"d98ec42f8b2caaac3489149cc32087f456548317e9b3de09fac799aca9d2fd41"
] | [
{
"edge_id": "d98ec42f8b2caaac3489149cc32087f456548317e9b3de09fac799aca9d2fd41",
"source_id": "Disease::DOID:2355",
"source_name": "anemia",
"relation_id": "Disease-associates-Gene",
"target_id": "Gene::9518",
"target_name": "GDF15"
}
] | [
"Disease::DOID:2355"
] | [
"Disease-associates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 11} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"Entrez Gene",
"UNSPECIFIED"
] | [
"CC BY 3.0",
"CC0 1.0",
"ODbL 1.0"
] | {"known_id": "Gene::9518", "query_direction": "inverse", "structural_split_key": "f1629912b7b5ea25ba19ed471e65f09919f12a1eb3505a159da02569ac6e7754"} |
0f7be8baf92f37ea3105a50b1e95af45da7a6c165c3b71f669db4c7e3b8b5a65 | 423f261db8dd85344139dd91bf4c07d3dab645438913efd3862175346fb2221b | [
{
"content": "Which disease is known to impact or be associated with smooth muscle tissue?",
"role": "user"
},
{
"content": "Chronic obstructive pulmonary disease is known to impact or be associated with smooth muscle tissue.",
"role": "assistant"
}
] | atomic_qa | train | b2f69bc5107d51587ea1abe8c30d2373099e2a8e71b55a267455acbe054fc4f8 | 1 | 1 | [
"Disease::DOID:3083",
"Anatomy::UBERON:0001135"
] | [
"33a9d93312e01772432de83a6cee7cf1f288cdfde7bc56296fbd5f015353348b"
] | [
{
"edge_id": "33a9d93312e01772432de83a6cee7cf1f288cdfde7bc56296fbd5f015353348b",
"source_id": "Disease::DOID:3083",
"source_name": "chronic obstructive pulmonary disease",
"relation_id": "Disease-localizes-Anatomy",
"target_id": "Anatomy::UBERON:0001135",
"target_name": "smooth muscle tissue... | [
"Disease::DOID:3083"
] | [
"Disease-localizes-Anatomy"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 28} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"MEDLINE cooccurrence",
"Uberon"
] | [
"CC BY 3.0",
"CC0 1.0"
] | {"known_id": "Anatomy::UBERON:0001135", "query_direction": "inverse", "structural_split_key": "c633aa59249a371199c07c170fda4d02b9f55d5f53b1818f653a15af1d68ad19"} |
d5cda34a076c6d6c18267a784fdcb1228f034f990466f6da533809a95585b4f2 | 59787cd114e87e498110769f6bad457d7f90e448e8ac39ad8684c43263bc257a | [
{
"content": "Which gene is downregulated by exposure to Cerulenin?",
"role": "user"
},
{
"content": "DEPDC1 is the gene that gets downregulated when exposed to Cerulenin.",
"role": "assistant"
}
] | atomic_qa | train | 6e846bdbd2f7f2dcf40596bdcfcb9013d311e6737ea24243590bd3f6aed2ba2b | 1 | 1 | [
"Compound::DB01034",
"Gene::55635"
] | [
"4956151f7cc07e478a5364908e869b9b0bcf7869bd36435fb7f0b2d4e0e04535"
] | [
{
"edge_id": "4956151f7cc07e478a5364908e869b9b0bcf7869bd36435fb7f0b2d4e0e04535",
"source_id": "Compound::DB01034",
"source_name": "Cerulenin",
"relation_id": "Compound-downregulates-Gene",
"target_id": "Gene::55635",
"target_name": "DEPDC1"
}
] | [
"Gene::55635"
] | [
"Compound-downregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 19} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"Entrez Gene",
"LINCS L1000"
] | [
"CC BY-NC 4.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Compound::DB01034", "query_direction": "forward", "structural_split_key": "bcab247b0265e2b0c12ea66d36fba741dc620add39609e09898e58d59d3afa7b"} |
4ebdc19389d238e348f9a454766e3236724c1765457e69a81fe38c97ba5328fb | ea05be0693e1358ac4d8eac10488f897624f84736fedb56a7904d4b087352e1c | [
{
"content": "Which compound causes IARS2 to be downregulated in samples?",
"role": "user"
},
{
"content": "IARS2 is downregulated in samples exposed to Methocarbamol.",
"role": "assistant"
}
] | atomic_qa | train | d8d7aab47d1c7704b36bb36e293c97bb80b9766a67d7643939c9205dffc494ee | 1 | 1 | [
"Compound::DB00423",
"Gene::55699"
] | [
"561ec3b796e1e3d78c2657551bfe04fd06a9740aea00b8bca2fbcec354b26d88"
] | [
{
"edge_id": "561ec3b796e1e3d78c2657551bfe04fd06a9740aea00b8bca2fbcec354b26d88",
"source_id": "Compound::DB00423",
"source_name": "Methocarbamol",
"relation_id": "Compound-downregulates-Gene",
"target_id": "Gene::55699",
"target_name": "IARS2"
}
] | [
"Compound::DB00423"
] | [
"Compound-downregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 17} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"Entrez Gene",
"LINCS L1000"
] | [
"CC BY-NC 4.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Gene::55699", "query_direction": "inverse", "structural_split_key": "2a8f98b73798f60e1c4dae189a31f5ab7f280b7bc87f627b946d93c7d0e6bc52"} |
27762b9f59b96f2d519b7052457760ff421cdabd955f75f9df0bec928589bffe | 97a2efb01a41e97ee05505c481d4d4b247652dc727ed363abc13c89593c05635 | [
{
"content": "What gene's expression is increased by exposure to Biperiden?",
"role": "user"
},
{
"content": "Exposure to Biperiden increases the expression of DDR1.",
"role": "assistant"
}
] | atomic_qa | train | 5945c8613c7bdfffc125b9223389fa184ecca22f6de47af13a399a1005fc939f | 1 | 1 | [
"Compound::DB00810",
"Gene::780"
] | [
"5e03c282fec29a62a170b46cfef2db1aa9ccaf1d0fe3568c5a50a13f8db63a72"
] | [
{
"edge_id": "5e03c282fec29a62a170b46cfef2db1aa9ccaf1d0fe3568c5a50a13f8db63a72",
"source_id": "Compound::DB00810",
"source_name": "Biperiden",
"relation_id": "Compound-upregulates-Gene",
"target_id": "Gene::780",
"target_name": "DDR1"
}
] | [
"Gene::780"
] | [
"Compound-upregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 17} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"Entrez Gene",
"LINCS L1000"
] | [
"CC BY-NC 4.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Compound::DB00810", "query_direction": "forward", "structural_split_key": "36bf3be64e129b09d76f7f06896896f18f3eb209b16089260d5e1a815d88f53a"} |
5b8c704f32881892022892782dd256cc4f42ee2e5bb0227766e627f2901b485a | 4e650808db94a5996bfd7351efa07c3a58fdfecf728af33614ad016e87bf470b | [
{
"content": "Which disease is known to affect the atrioventricular node?",
"role": "user"
},
{
"content": "Coronary artery disease is known to affect the atrioventricular node.",
"role": "assistant"
}
] | atomic_qa | train | 6f8a5a4b34c0b48ad6f367116ee8dc479afd92f1bf53863db1273fda061f2568 | 1 | 1 | [
"Disease::DOID:3393",
"Anatomy::UBERON:0002352"
] | [
"e9743818a820a3bd068af1dab2ca50bccf02176ef86eb6c04188124731540ced"
] | [
{
"edge_id": "e9743818a820a3bd068af1dab2ca50bccf02176ef86eb6c04188124731540ced",
"source_id": "Disease::DOID:3393",
"source_name": "coronary artery disease",
"relation_id": "Disease-localizes-Anatomy",
"target_id": "Anatomy::UBERON:0002352",
"target_name": "atrioventricular node"
}
] | [
"Disease::DOID:3393"
] | [
"Disease-localizes-Anatomy"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 19} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"MEDLINE cooccurrence",
"Uberon"
] | [
"CC BY 3.0",
"CC0 1.0"
] | {"known_id": "Anatomy::UBERON:0002352", "query_direction": "inverse", "structural_split_key": "3947ef28450cb7ae498303834d21b223abfdc9137d95d6f9e2ecc706d19206fa"} |
37f753ad7ceee37ce5262f5c5f05e03961de8a810b02c8b91b3e441652f320d2 | f428b3eee7a4639a22237331f4492b20ec30e7cb9e9d7b97fe22a89b500c6787 | [
{
"content": "Which compound binds to the protein product of ATP5D?",
"role": "user"
},
{
"content": "Halothane",
"role": "assistant"
}
] | atomic_qa | train | a53a5aa352871e75f7aef61f6d12a5ece16e6ab2232bed14953d838ea95afc63 | 1 | 1 | [
"Compound::DB01159",
"Gene::513"
] | [
"405aaa0c79aa857e7914e043e9c609abfeb6706900d4f3d014715a9547b4fbea"
] | [
{
"edge_id": "405aaa0c79aa857e7914e043e9c609abfeb6706900d4f3d014715a9547b4fbea",
"source_id": "Compound::DB01159",
"source_name": "Halothane",
"relation_id": "Compound-binds-Gene",
"target_id": "Gene::513",
"target_name": "ATP5D"
}
] | [
"Compound::DB01159"
] | [
"Compound-binds-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 10} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"Entrez Gene",
"UNSPECIFIED"
] | [
"CC BY-NC 4.0",
"CC0 1.0"
] | {"known_id": "Gene::513", "query_direction": "inverse", "structural_split_key": "d33f6a36f512d2d7f3d43a9565897d7797b23e7bddf7729af8a0e41e264be10b"} |
13ba65b3e7254a7d16cdd87095467eda9f3c3858b2428d0d160a6a6980e1b6a7 | 93fd724eb90e9975c7cb68cf467b5501befc54d34a453ac98b1111fdd41273bb | [
{
"content": "Which gene's protein products physically interact with those of ADRBK2?",
"role": "user"
},
{
"content": "BDKRB2",
"role": "assistant"
}
] | atomic_qa | train | 8dd3a87da5c7e6436296125f5346aa39992f3d9e7e1947fc0bac10477e25cd10 | 1 | 1 | [
"Gene::157",
"Gene::624"
] | [
"ff6f67e7a296f7670990c6bee95a79bc69948ea48507d926008d05b85daf674b"
] | [
{
"edge_id": "ff6f67e7a296f7670990c6bee95a79bc69948ea48507d926008d05b85daf674b",
"source_id": "Gene::157",
"source_name": "ADRBK2",
"relation_id": "Gene-interacts-Gene",
"target_id": "Gene::624",
"target_name": "BDKRB2"
}
] | [
"Gene::624"
] | [
"Gene-interacts-Gene"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 11} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Entrez Gene",
"UNSPECIFIED"
] | [
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Gene::157", "query_direction": "forward", "structural_split_key": "ca708cd90e41986fba48982044e315ab8bb7eed311aefc7516b6f64c6e9c87f7"} |
3f108d9e632ba5147ecf186776746fe78d4d9135aeccee9a18cddfd2b59a5dda | 3e8d95a39a6d49829ac44c078029e8e3d99d03b25f240603a82e436e5391d8c7 | [
{
"content": "Which compound is chemically similar to Methyldopa?",
"role": "user"
},
{
"content": "Methyldopa is chemically similar to Mesalazine.",
"role": "assistant"
}
] | atomic_qa | train | bca01baed157300f48a237702976c7476b2d7fad159f61463b0e242e2c7616a3 | 1 | 1 | [
"Compound::DB00968",
"Compound::DB00244"
] | [
"c3584db531cec52ad27bfc25f213f631ef7ba5858f33488d16792065934a9542"
] | [
{
"edge_id": "c3584db531cec52ad27bfc25f213f631ef7ba5858f33488d16792065934a9542",
"source_id": "Compound::DB00968",
"source_name": "Methyldopa",
"relation_id": "Compound-resembles-Compound",
"target_id": "Compound::DB00244",
"target_name": "Mesalazine"
}
] | [
"Compound::DB00244"
] | [
"Compound-resembles-Compound"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 13} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Dice similarity of ECFPs",
"DrugBank"
] | [
"CC BY-NC 4.0",
"CC0 1.0"
] | {"known_id": "Compound::DB00968", "query_direction": "forward", "structural_split_key": "72f56dd6a2a850c4bbb193551c9a0aad5a35d056a6c2897972dd31df52891542"} |
d33f5f31b6415da7c40e830756bedbb3bf1295051ab45da68abea2b0af36f520 | 13baaea1acb3f7f9b6f33079bf81a44e8a2c238ca927ae4785ffb324bb2c94c9 | [
{
"content": "Which part of the body is affected by or related to vascular cancer?",
"role": "user"
},
{
"content": "Vascular cancer affects or is related to the portal vein.",
"role": "assistant"
}
] | atomic_qa | train | d88f95c9853a63e3d6ec4d9224d6152bba1715777aa05af312630ce0c48f4075 | 1 | 1 | [
"Disease::DOID:175",
"Anatomy::UBERON:0002017"
] | [
"b9b5501f034cf18e9f6bec3aaa1a0f0bc0a7fea725a91e57ba625b58341fa6ff"
] | [
{
"edge_id": "b9b5501f034cf18e9f6bec3aaa1a0f0bc0a7fea725a91e57ba625b58341fa6ff",
"source_id": "Disease::DOID:175",
"source_name": "vascular cancer",
"relation_id": "Disease-localizes-Anatomy",
"target_id": "Anatomy::UBERON:0002017",
"target_name": "portal vein"
}
] | [
"Anatomy::UBERON:0002017"
] | [
"Disease-localizes-Anatomy"
] | none | llm | fixed-v3+natural-conversation-v10 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 23} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"MEDLINE cooccurrence",
"Uberon"
] | [
"CC BY 3.0",
"CC0 1.0"
] | {"known_id": "Disease::DOID:175", "query_direction": "forward", "structural_split_key": "9e27b7b90d5e5b7ea9ec2c9c4de1542bee7c9368ca3cea52a00f72fd39a72ab4"} |
End of preview. Expand in Data Studio
synth-kg-text: hetionet v1.0
This repository contains chat-style supervised fine-tuning data automatically generated starting from Hetionet knowledge graph.
- Knowledge graph: hetionet v1.0
- Generator model: Qwen/Qwen3.6-35B-A3B
- Configuration hash: 48deb72be693b8d0f07ce603704e9848c8b7730a2034e06fc1c2e333015cff83
Splits
| Split | Rows |
|---|---|
| train | 439906 |
| validation | 24525 |
| test | 24389 |
| seen_fact_unseen_phrasing | derived evaluation subset |
| compositional | derived evaluation subset |
The metadata directory contains the resolved configuration, prompt snapshots, build manifest, and generation report needed to audit the run. Individual records retain graph provenance, licenses, grounding identifiers, and validation results.
Load
from datasets import load_dataset
dataset = load_dataset("giannor/synth-kg-text-hetionet")
- Downloads last month
- 80